Hemorrhage in mouse tumors induced by dodecaborate cluster lipids intended for boron neutron capture therapy [PDF]
The potential of boron-containing lipids with three different structures, which were intended for use in boron neutron capture therapy, was investigated. All three types of boron lipids contained the anionic dodecaborate cluster as the headgroup.
Detlef Gabel +8 more
core +2 more sources
Modulation of γ-Secretase Activity by a Carborane-Based Flurbiprofen Analogue [PDF]
All over the world, societies are facing rapidly aging populations combined with a growing number of patients suffering from Alzheimer’s disease (AD). One focus in pharmaceutical research to address this issue is on the reduction of the longer amyloid-β (
Basset, Gabriele +9 more
core +1 more source
Thermally Activated Delayed Fluorescence and Beyond. Photophysics and Material Design Strategies.
Photophysical properties of TADF molecules are determined by characteristic parameters that are discussed in detail(. Moreover, using femtosecond time‐resolved spectroscopy, quantum mechanical considerations, and state‐of‐art calculations, deeper understanding allows us to design breakthrough Cu(I) and organic TADF‐ OLED materials. For the latter ones,
Hartmut Yersin, Uwe Monkowius
wiley +1 more source
Synthesis, Characterization and Evaluation of Central Nervous System Targeted Metallocarborane Complexes [PDF]
A series of new methodologies to link a neurotransmitter receptor targeting vector (WAY) to carboranes and the preparation of the corresponding metallocarboranes (M = Re, 99mTc) as a new class of organometallic CNS imaging probes is described.
Louie, Anika S.
core
Sviluppo e applicazioni della boron neutron capture therapy [PDF]
La Boron Neutron Capture Therapy è una tecnica terapeutica altamente selettiva, utilizzata in oncologia, che si basa sulla reazione di cattura neutronica 10B(n,α)7Li .
Guidi, Claretta
core
Final Report for research grant entitled "Development of Reagents for Application of At-211 and Bi-213 to Targeted Radiotherapy of Cancer" [PDF]
This grant was a one-year extension of another grant with the same title (DE-FG03-98ER62572). The objective of the studies was to continue in vivo evaluation of reagents to determine which changes in structure were most favorable for in vivo use.
Wilbur, D. Scott
core +1 more source
The Preparation of Metallocarborane and Iodinated Carborane Amino Acid Analogues for Molecular Imaging and Therapy [PDF]
This thesis demonstrates the versatility of the carborane cage by qsing a known carborane containing analogue of the amino acid phenylalanine, carborananylalanine (Car5) as a novel platform for radio labelling targeting vectors with both 99mTc and 125I ...
Gullon, Janet Teri
core
Phosphorus chalcogenide‐rich polymer networks swell in polar aprotic solvents, and remove metals from solutions. ABSTRACT Quaternary mixtures of primary phosphine, chalcogen, diimine, and triimine were employed in polymerization reactions to give α‐aminophosphine chalcogenide polymer networks.
Jan‐Willem Lamberink‐Ilupeju +7 more
wiley +1 more source
Tethered N-Heterocyclic Carbene-Carboranyl Silver Complexes for Cancer Therapy [PDF]
Silver complexes of tethered N-heterocyclic carbene-carboranyl ligands have been prepared and fully characterized. The first example of silver bonded directly to the cage of o-carborane has been identified in the solid state. The presence of a carboranyl
Atallah, S +7 more
core +2 more sources
The Wade's rules and Lipscomb's styx approach constitute a conceptual basis of chemical bonding in closo hydroborane clusters and similar compounds. Based on 3‐center electron sharing indices obtained from DFT wavefunctions, the DR approach for analysis of multicenter bonding in clusters and intermetallic compounds is presented.
Frank R. Wagner
wiley +1 more source

