Results 71 to 80 of about 757 (176)

The Possible Aromatic Conjugation via the Different Edges of (Car)Borane Clusters: Can the Relationship Between 3D and 2D Aromatic Systems Be Reconciled?

Chemistry – A European Journal, Volume 30, Issue 61, November 4, 2024.
The interaction between the 2D and 3D units in the (car)borane‐fused 2D ring systems was investigated computationally. Although aromatic conjugation can be excluded, other factors, such as negative hyperconjugation and ring strain, play a crucial role in the overall stability of these systems and should be taken into account during their investigation.
Dániel Buzsáki, Dalma Gál, Zsófia Harcsa‐Pintér, László Kalabay, Zsolt Kelemen   +4 more
wiley   +1 more source

Bis(silylene)‐Stabilized Monovalent Nitrogen Complexes [PDF]

, 2020
The first series of bis(silylene)‐stabilized nitrogen(I) compounds is described. Starting from the 1,2‐bis(N‐heterocyclic silylenyl) 1,2‐dicarba‐closo‐dedocaborane(12) scaffold 1, [1,2‐(LSi)2C2B10H10; L=PhC(NtBu)2], reaction with adamantyl azide (AdN3 ...
Driess, Matthias, Lorent, Christian, Ruzicka, Ales, Szilvási, Tibor, Xiong, Yun, Yao, Shenglai   +5 more
core   +1 more source

Isoniazid Hybrids As Potential Antitubercular Agents

ChemistrySelect, Volume 9, Issue 38, October 11, 2024.
Molecular hybridization is a rational drug design strategy that combines two or more covalently binding pharmacological agents into a single multifunctional molecule. The present review discusses the recent functionalizing of isoniazid to new hybrids tackling the menace of various forms of drug‐resistant tuberculosis and generating potential leads for ...
Sahil Mishra, Gobind Kumar, Parvesh Singh   +2 more
wiley   +1 more source

Cobaltabis(Dicarbollide) [o-COSAN]⁻ for Boron Neutron Capture Therapy of Head and Neck Cancer: Biodistribution and Irradiation Studies in an Experimental Oral Cancer Model

Pharmaceuticals
Background: Boron neutron capture therapy (BNCT) is a tumor-selective particle radiotherapy that combines preferential boron accumulation in tumors and neutron irradiation.
Mónica A. Palmieri, Andrea Monti Hughes, Verónica A. Trivillin, Marcela A. Garabalino, Paula S. Ramos, Silvia I. Thorp, Paula Curotto, Emiliano C. C. Pozzi, Miquel Nuez Martínez, Francesc Teixidor, Clara Viñas, Amanda E. Schwint   +11 more
doaj   +1 more source

Advancements in the synthesis and biological properties of carboranes and high‑boron related compounds: a comprehensive exploration with emphasis on BNCT applications [PDF]

Since Locher proposed the concept of boron neutron capture therapy (BNCT) in 1936, it has become a great challenge in the field of medicinal chemistry. The great dare has been to obtain boron-containing compounds that selectively accumulate in the organ ...
Cerecetto, Hugo, Couto, Marcos
core   +1 more source

Well Defined Rich Electronic Structure: Facile Approach for Nido-Carborane Fused Azaspirodecaniums in Water Solution

Journal of the Brazilian Chemical Society, 2020
A novel bis-dumbbell shape of a multi cation around a azaspirodecanium combined with nido-carborane was prepared in a single step in good yield starting from pyrrolidine and 1,3-dichloropropane to give one compound and from piperidine and 1,4-dichlorobutane to give the other.
Zhixiang Lv, Zhou Wang, Fuyan Xiao, Guofan Jin   +3 more
openaire   +3 more sources

The Synthesis and Characterization of Carborane and Metallocarborane-Carbohydrate Conjugates [PDF]

, 2008
This thesis describes the synthesis and characterization of a series of carborane and metallocarborane-carbohydrate conjugates as model systems for developing a novel class of radiophannaceuticals.
Green, Andrew
core  

An Examination Between Neighborhood Characteristics and Alzheimer’s Disease and Related Dementias and Caregiver Mental Health in South Carolina [PDF]

, 2020
Carboranes are of topical interest due to their unique structures and applications in the fields of catalysis, polymers, material sciences and supramolecular chemistry.
Islam, Mohammad Jahirul
core   +1 more source

Synthesis, characterization and biological studies of carboranyl-porphyrin bioconjugates for treatment of brain tumors [PDF]

, 2013
Chapter 1 gives a brief introduction to brain tumors, approaches to deliver drug across the blood brain barrier (BBB), boron neutron capture therapy (BNCT) for brain tumors, application of carboranyl derivatives in attempt to treat brain tumors using ...
Bhupathiraju, Naga Venkata Satya Dinesh Kumar
core   +2 more sources

Fe 3 O 4 nanoparticles for complex targeted delivery and boron neutron capture therapy [PDF]

, 2019
Magnetic Fe 3 O 4 nanoparticles (NPs) and their surface modification with therapeutic substances are of great interest, especially drug delivery for cancer therapy, including boron-neutron capture therapy (BNCT).
Anisovich, M., Dukenbayev, K., Gorin, Y. G., Kaniukov, E. Y., Korolkov, I. V., Kozlovskiy, A. L., Molardi, C., Shumskaya, E. E., Tishkevich, D. I., Tosi, D., Trukhanov, A. V., Trukhanov, S. V., Vinnik, D. A., Zdorovets, M. V.   +13 more
core   +1 more source