Results 101 to 110 of about 93,808 (329)

Antilymphoid antibody preconditioning and tacrolimus monotherapy for pediatric kidney transplantation [PDF]

, 2006
Objective: Heavy post-transplant immunosuppression may contribute to long-term immunosuppression dependence by subverting tolerogenic mechanisms; thus, we sought to determine if this undesirable consequence could be mitigated by pretransplant lymphoid ...
Abhay N. Vats, Adrianna Zeevi, Akhtar S. Khan, Amadeo Marcos, Amit Basu, Bartosh, Calne, Calne, Chakrabarti, Corde McFeaters, Demetrius Ellis, Edward A. Gray, Fine, Gerri James, Halloran, Henkie P. Tan, Jensen, Kirk, Knechtle, Lilly, Mary Jo Grosso, McCurry, Michael L. Moritz, Mueller, Najarian, Nankivell, Purighalla, Randhawa, Reyes, Riley, Ron Shapiro, Sarwal, Shapiro, Shapiro, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Stuart, Thomas E. Starzl, Todo, Waldmann, Williams   +52 more
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Antihypertensive therapy for pregnancy hypertension and implications for fetal and neonatal heart rate monitoring: A systematic review of randomized trials and observational studies

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Trials are mostly reassuring regarding antihypertensive effects on fetal (FHR) or neonatal heart rate (neoHR), but observational studies raise concerns about beta‐blockers, particularly the alpha/beta‐blocker labetalol. Clinicians should ascribe adverse fetal or neonatal heart rate effects to evolving underlying placental dysfunction or newborn illness,
Akalya Ganeshamoorthy, Omiete Fubara Duke, Hiten D. Mistry, Jeffrey N. Bone, Marianne Vidler, Edgardo Abalos, Katie Badawy, Asma Khalil, Peter von Dadelszen, Laura A. Magee   +9 more
wiley   +1 more source

Clinically applicable GABA receptor positive allosteric modulators promote ß-cell replication. [PDF]

, 2017
A key goal of diabetes research is to develop treatments to safely promote human ß-cell replication. It has recently become appreciated that activation of γ-aminobutyric acid receptors (GABA-Rs) on ß-cells can promote their survival and replication.
Dang, Hoa, Kaufman, Daniel L, Middleton, Blake, Tian, Jide   +3 more
core   +1 more source

Risk of preterm delivery in women with a history of preterm labor successfully arrested by tocolytic treatment in their previous pregnancy

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
A history of preterm labor that was successfully managed and resulted in a term delivery should be carefully documented, as these women continue to have an elevated risk of preterm birth in subsequent pregnancies. Abstract Introduction We aimed to determine if women with a history of preterm labor successfully arrested by tocolytic treatment who gave ...
Thibaud Quibel, Anne Rousseau, Claire Thuillier, Mireille Ruiz, Patrick Rozenberg   +4 more
wiley   +1 more source

Soybean Isoflavones Eliminate Nifedipine-Induced Flushing of Tail Skin in Ovariectomized Mice

Journal of Pharmacological Sciences, 2004
Hot flushes are one of the most frequent symptoms in menopausal women. We investigated effect of soybean isoflavones (Soyaflavone HG) on nifedipine-induced flushing in ovariectomized mice.
Mamiko Kai, Atsushi Yamauchi, Koji Tominaga, Ayako Koga, Hisashi Kai, Yasufumi Kataoka   +5 more
doaj   +1 more source

Chronic beta-adrenoceptor blockade and human atrial cell electrophysiology: evidence of pharmacological remodelling [PDF]

, 2003
<b>Objective:</b> Chronic beta-adrenoceptor antagonist (β-blocker) treatment reduces the incidence of reversion to AF in patients, possibly via an adaptive myocardial response.
Kane, K.A., Norrie, J., Rankin, A.C., Russell, J.A., Workman, A.J.   +4 more
core   +1 more source

Human hypoxia models in aerospace medicine: Potential applications for human pharmacological research

British Journal of Clinical Pharmacology, EarlyView.
Aerospace medicine required controlled terrestrial models to investigate influences of altered atmosphere conditions, such as hypoxia, on human health and performance. These models could potentially be expanded to encompass disease conditions or treatment targets regulated through hypoxia or hypercapnia.
Titiaan E. Post, Cayla Denney, Adam Cohen, Jens Jordan, Ulrich Limper   +4 more
wiley   +1 more source

Promotion of cutaneous penetration of nifedipine for nanoemulsion

Brazilian Journal of Pharmaceutical Sciences, 2017
This article reports the development and characterization of a nanoemulsion (NE) able to improve the cutaneous penetration of nifedipine. NE with nifedipine was development and characterized, presenting droplet size of 20 nm with low polydispersity index
Paula de Oliveira Arantes, Quesia Nery dos Santos, Zaida Maria Faria de Freitas, Alexandre dos Santos Pyrrho, Cristal Cerqueira-Coutinho, Ana Lucia Vazquez Villa, Elisabete Pereira dos Santos, Eduardo Ricci-Júnior   +7 more
doaj   +1 more source

The delayed rectifier potassium conductance in the sarcolemma and the transverse tubular system membranes of mammalian skeletal muscle fibers. [PDF]

, 2012
A two-microelectrode voltage clamp and optical measurements of membrane potential changes at the transverse tubular system (TTS) were used to characterize delayed rectifier K currents (IK(V)) in murine muscle fibers stained with the potentiometric dye di-
DiFranco, Marino, Quinonez, Marbella, Vergara, Julio L   +2 more
core   +1 more source

Pre-eclampsia toxaemia [PDF]

, 2013
A 33 year old primagravida rhesus positive woman was referred to the Emergency Department by her family doctor at 27 weeks gestation. At 25 weeks of gestation, she had been diagnosed with hypertension and was started on labetalol therapy.
Bugeja, Roberta, Galdes, Caroline
core