The Role of Oxidative Stress in Periodontitis
Journal of Periodontal Research, EarlyView.Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon +3 more
wiley +1 more source
Nifedipine-induced Hyperglycaemia in an Infant: A Case Report
Nigerian Journal of PaediatricsSummary: This case report describes reversible hyperglycaemia in a severely ill six-month old Saudi boy treated with nifedipine for hypertension. Hyperglycaemia became manifest on the second day of treatment with nifedipine and was not dose-related ...
Jobran Al Qhtani +6 more
doaj
Nifedipine kinetics in the rat and relationship between its serum concentrations and uterine and cardiovascular effects [PDF]
, 1988 S. J. Downing, Michael A. Hollingsworth
openalex +1 more source
Smooth Muscle Mechanosensitivity Generates and Maintains Pressure Gradients Across the Intestine
Neurogastroenterology &Motility, EarlyView.Mechanosensitivity of the smooth muscle induces a positive‐feedback loop that spontaneously generates pressure gradients across gut segments and stabilizes initially applied pressure gradients. It can act jointly or compete with the pressure gradient induced by directional peristaltic waves.
Richard J. Amedzrovi Agbesi +2 more
wiley +1 more source
Journal of Enzyme Inhibition and Medicinal Chemistry, 2017 Context: Calcium channel blockers may theoretically exhibit relaxing effects not only on vascular smooth muscle but also on airway smooth muscle. Objective: To investigate possible effects of nifedipine on respiratory mechanics in the rat.
Alessandro Rubini +3 more
doaj +1 more source
Calcium regulation of muscle spindle mechanosensory afferent function. [PDF]
Exp PhysiolAbstract Extracellular calcium is crucial for the normal function of muscle spindle sensory afferents. They express multiple calcium buffering proteins. Extracellular calcium is essential for recycling of synaptic‐like vesicles (SLVs) in the terminals and for the stretch‐evoked inward calcium current of the receptor potential.
Simon A +5 more
europepmc +2 more sources
Nifedipine inhibits superoxide production induced by pulsatile stretch in human aortic endothelial cells [PDF]
, 2017 Dihydropiridine calcium channel blocker nifedipine restores nitric oxide-mediated vasodilation in human hypertension. The mechanims involved have not been fully characterized but may relate to endothelial protection.
Cosentino, Francesco +2 more
core
Paediatric and Perinatal Epidemiology, EarlyView.ABSTRACT Background Data on antihypertensive medication for non‐severe gestational hypertension may suffer from immortal time and selection bias. Emulating target trials can prevent these biases by aligning follow‐up with treatment initiation. Objectives We estimated the safety of antihypertensive medication initiation for the treatment of non‐severe ...
Julia D. DiTosto +12 more
wiley +1 more source
TOXICOLOGICAL STUDY OF MEBUDIPINE AND DIBUDINE, TWO NEW CALCIUMCHANNEL BLOCKERS, IN SACCHAROMYCES CERVISES AND ISOLATED RAT HEPATOCYTES CELLS INVITRO [PDF]
Mebudipine and Dibudipine are two new calcium antagosists used in laboratory animals. Toxicological testing were evaluated in cultured mouse cells in‐vitro and on growth yeast cells . It is shown that in these two system it is safe and no toxicological
بهلولی, شهاب +4 more
core
A randomized placebo-controlled study on the effect of nifedipine on coronary endothelial function and plaque formation in patients with coronary artery disease: the ENCORE II study [PDF]
, 2017 Aims Endothelial dysfunction and plaque formation are features of atherosclerosis. Inhibition of L-type calcium channels or HMG-CoA pathway improves endothelial function and reduces plaque size.
Bischoff, Karl-Otto +11 more
core