Results 51 to 60 of about 67,449 (286)
Animal Models and Experimental Medicine, EarlyView.The example of the time dependent fluctuation of systolic pressure on rat arterial pulse waveform in ms. The four levels of the systolic pressure fluctuation show di‐gital, tri‐gital and tetra‐gital fluctuation. The red dots represent particular heartbeats. Abstract Background An arterial stiffness is an indicator of many cardiovascular diseases.
Anton Misak +3 more
wiley +1 more source
SAFETY EVALUATION OF STATIN IN YOGYAKARTA, INDONESIA [PDF]
, 2009 Background : The 3-hydroxy-3-methylglutaryl-coenzyme (HMG-Co-A) reductase inhibitors, also known as statins, are the most effective class of drugs for lowering serum Low-Density Lipoprotein cholesterol (LDL-c)concentrations.
Anni, Anni +3 more
core
Nifedipine promotes the proliferation and migration of breast cancer cells.
PLoS ONE, 2014 Nifedipine is widely used as a calcium channel blocker (CCB) to treat angina and hypertension,but it is controversial with respect the risk of stimulation of cancers. In this study, we demonstrated that nifedipine promoted the proliferation and migration
Dong-Qing Guo +3 more
doaj +1 more source
Nifedipine treatment reduces resting calcium concentration, oxidative and apoptotic gene expression, and improves muscle function in dystrophic mdx mice. [PDF]
PLoS ONE, 2013 Duchenne Muscular Dystrophy (DMD) is a recessive X-linked genetic disease, caused by mutations in the gene encoding dystrophin. DMD is characterized in humans and in mdx mice by a severe and progressive destruction of muscle fibers, inflammation ...
Francisco Altamirano +6 more
doaj +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims Hypertension is a leading modifiable risk factor for cardiovascular mortality worldwide. This study aimed to evaluate 25‐year trends in antihypertensive agent (AHA) utilization in Croatia between 2000 and 2024. Methods We conducted a national, population‐based analysis using IMS and IQVIA pharmaceutical databases.
Andrej Belančić +4 more
wiley +1 more source
eNOS-dependent antisenscence effect of a calcium channel blocker in human endothelial cells. [PDF]
PLoS ONE, 2014 Senescence of vascular endothelial cells is an important contributor to the pathogenesis of age-associated vascular disorders such as atherosclerosis. We investigated the effects of antihypertensive agents on high glucose-induced cellular senescence in ...
Toshio Hayashi +6 more
doaj +1 more source
Frontiers in Pharmacology, 2021 Purpose: The drug-drug interactions (DDIs) of tacrolimus greatly contributed to pharmacokinetic variability. Nifedipine, frequently prescribed for hypertension, is a competitive CYP3A5 inhibitor which can inhibit tacrolimus metabolism.
Yilei Yang +12 more
doaj +1 more source
The effect of Erbium:YAG Laser for the Fibronectin Expression in Gingival Epithelium with Nifedipine induced Gingival Overgrowth [PDF]
, 2021 Rasha Mostafa, Marwa Tawfiq
openalex +1 more source
Voclosporin‐induced gingival enlargement: A case report
Clinical Advances in Periodontics, EarlyView.Abstract Background Drug‐influenced gingival enlargement (DIGE) is a recognized adverse effect of certain medications, particularly immunosuppressants like cyclosporin and tacrolimus. However, there have been no documented cases of DIGE associated with voclosporin, a newer calcineurin inhibitor used primarily to treat lupus nephritis.
Francesca Racca +2 more
wiley +1 more source
Safety of nifedipine GITS in stable angina: The ACTION trial [PDF]
, 2006 Aim: We describe the safety profile of nifedipine GITS as assessed from adverse events reported in the ACTION trial in which 7,665 patients with stable, symptomatic coronary artery disease were randomly assigned nifedipine GITS or placebo and followed ...
Brouwer, S. (Sophie) de +5 more
core +3 more sources