Results 51 to 60 of about 93,808 (329)

New Perspectives on Semiconducting Conjugated Oligomers for Neuromodulation in Hydra vulgaris

Advanced Materials Interfaces, EarlyView.
Semiconducting organic compounds, thiophene‐based, modify the rhythmic electrical activity of the cnidarian Hydra vulgaris acting on specific neuronal circuits. The ETE‐S trimer also forms electronically conducting wires in the living tissues of the animal.
Giuseppina Tommasini, Mariarosaria De Simone, Martina Blasio, Claudia Zenna, Angela Tino, Eleni Stavrinidou, Silvia Santillo, Claudia Tortiglione   +7 more
wiley   +1 more source

Nifedipine-Induced Changes in the Electrohysterogram of Preterm Contractions: Feasibility in Clinical Practice

Obstetrics and Gynecology International, 2010
Objective. Evaluating changes in the power spectral density (PSD) peak frequency of the electrohysterogram (EHG) caused by nifedipine in women with preterm contractions. Methods.
Maartje P. G. C. Vinken, C. Rabotti, M. Mischi, J. O. E. H. van Laar, S. G. Oei   +4 more
doaj   +1 more source

Harnessing the Biological Responses Induced by Nanomaterials for Enhanced Cancer Therapy

Aggregate, EarlyView.
Nanomaterial (NM)‐induced toxicity can be strategically repurposed for cancer therapy. This review summarizes the mechanism by which NMs selectively activate specific cellular processes to regulate cell fate independently. We also discussed how NMs‐induced biological responses can be leveraged as therapeutic strategies for cancer treatment.
Liting Wang, Hao Fu, Jiangtao Lin, Meng Zhao, Chuanrong Chen, Hongze Liao, Yourong Duan   +6 more
wiley   +1 more source

MODULATION OF CALCIUM CHANNELS IN ARTERIAL SMOOTH-MUSCLE CELLS BY DIHYDROPYRIDINE ENANTIOMERS [PDF]

, 1993
The actions of the optical enantiomers of BAY K 8644 and Sandoz 202,791 were studied on barium inward currents recorded using the whole-cell configuration of the patch clamp technique from enzymatically isolated smooth muscle cells from the rabbit ear ...
Bolton, TB, Hering, S, Hughes, AD, Timin, EN   +3 more
core   +1 more source

Synthesis of Novel Dihydropyridine‐Iminium Salts Containing a Selenazine Core

Asian Journal of Organic Chemistry, EarlyView.
An efficient method to develop novel dihydropyrido[3,2‐e][1,3]selenazines iminium salts. A comparative study of the key reagent selenourea towards thiourea and urea was carried out to assess the contribution of chalcogen to the pathway. DFT (density functional theory) calculations have predicted the optimized minimum energy structure for the hybrid ...
Reinier Lemos, Mauro De Nisco, Yoana Pérez‐Badell, Gabriella Pinto, Marco Morelli, Margarita Suárez, Silvana Pedatella   +6 more
wiley   +1 more source

A correlative model to predict in vivo AUC for nanosystem drug delivery with release rate-limited absorption [PDF]

, 2012
Purpose. Drug release from nanosystems at the sites of either absorption or effect biophase is a major determinant of its biological action. Thus, in vitro drug release is of paramount importance in gaining insight for the systems performance in vivo ...
Adibkia, Khosro, Barzegar-Jalali, Azim, Barzegar-Jalali, Mohammad, Mohammadi, Ghobad, Mohammadi, Kaivan, Nokhodchi, Ali, Valizadeh, Hadi   +6 more
core   +3 more sources

Bioprinting‐Assisted Tissue Assembly to Investigate Endothelial Cell Contributions in Cardiac Fibrosis and Focal Fibrosis Modeling

Advanced NanoBiomed Research, EarlyView.
GA: Bioprinting‐assisted tissue assembly, a method for generating versatile and complex tissue constructs, is employed to investigate the contribution of endothelial cells (ECs) in cardiac fibrosis. ECs modulate fibrotic responses not only by preventing significant tissue stiffening and contractile impairment but also by exhibiting endothelial‐to ...
Dong Gyu Hwang, Hwanyong Choi, Myungji Kim, Minji Kim, Donghwan Kim, Jinseon Park, Jinah Jang   +6 more
wiley   +1 more source

Trends in 25 years of antihypertensive agent utilization in Croatia – an alert for scientific community and healthcare providers

British Journal of Clinical Pharmacology, EarlyView.
Aims Hypertension is a leading modifiable risk factor for cardiovascular mortality worldwide. This study aimed to evaluate 25‐year trends in antihypertensive agent (AHA) utilization in Croatia between 2000 and 2024. Methods We conducted a national, population‐based analysis using IMS and IQVIA pharmaceutical databases.
Andrej Belančić, Marta Kučan Štiglić, Ana Jelaković, Bojan Jelaković, Dinko Vitezić   +4 more
wiley   +1 more source

Efficacy and safety of oral nifedipine with or without vaginal progesterone in the management of threatened preterm labor

International Journal of Reproductive BioMedicine, 2019
Background Preterm labor (PTL) is a serious emergency wherein robust management is imperative for achieving improved outcome. Objective To evaluate the efficacy and safety of nifedipine alone vs nifedipine with vaginal ...
Bushra Ashraf
doaj   +1 more source

Oral nifedipine may be a preferential option for treating acute severe hypertension during pregnancy: a meta-analysis

Hypertension in Pregnancy, 2023
Aim To compare oral nifedipine and intravenous labetalol in the treatment of acute severe hypertension in pregnancy (SHP). Methods The primary outcomes were the required time to achieve target blood pressure (RTATBP), systolic blood pressure (SBP) and ...
Minghui Ou, Futao Zhang, Shichao Cui, Shibo Zhao, Yan Yu   +4 more
doaj   +1 more source