Results 51 to 60 of about 37,594 (237)

ESTIMATION OF ANTIHYPERTENSIVE EFFECT EQUABILITY FOR TWO PRESENTATIONS OF NIFEDIPINE WITH DAILY BLOOD PRESSURE MONITORING

open access: yesРациональная фармакотерапия в кардиологии, 2015
Aim. To compare information value of antihypertensive effect equability parameters for two drug formulations of nifedipine: long-acting one (nifedipine-XL) and short-acting one (nifedipine-sa).Material and methods. 147 patients with arterial hypertension
V. M. Gorbunov   +2 more
doaj   +1 more source

Cardiac dysfunction during adverse maternal outcomes in hypertensive disorders of pregnancy

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
In pregnancies complicated by hypertensive disorders, peripartum adverse maternal outcomes are associated with diastolic cardiac dysfunction. Elevated E/e' ratio and left atrial volume index highlight the need for targeted cardiovascular monitoring and long‐term follow‐up.
Veronica Giorgione   +5 more
wiley   +1 more source

A quad‐cistronic fluorescent biosensor system for real‐time detection of subcellular Ca2+ signals

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose The calcium ion (Ca2+) is a versatile cellular messenger regulating a variety of biological processes. Compounds modulating subcellular Ca2+ signals hold substantial pharmacological potential. Advances in fluorescent biosensors have revolutionised Ca2+ imaging.
Anna Lischnig   +7 more
wiley   +1 more source

Plateau hypoxia attenuates the metabolic activity of intestinal flora to enhance the bioavailability of nifedipine

open access: yesDrug Delivery, 2018
Nifedipine is completely absorbed by the gastrointestinal tract and its pharmacokinetics and metabolism may be influenced by microorganisms. If gut microbes are involved in the metabolism of nifedipine, plateau hypoxia may regulate the bioavailability ...
Juanhong Zhang   +5 more
doaj   +1 more source

TREATMENT OF GINGIVAL HYPERPLASIA INDUCED BY NIFEDIPINE

open access: yesJournal of Dentistry Indonesia, 2015
The use of Nifedipine as cardiovascular therapy is proven to be the cause of gingival hyperplasia. The objective of this present case is to report the gingival hyperplasia induced by nifedipine, and the best management suggested.
Mitayani Restuning Kusumarini   +1 more
doaj   +1 more source

Lactate Accelerates Early Angiogenesis and Bone Regeneration Through Macrophage M1 Polarisation

open access: yesCell Proliferation, EarlyView.
During the early stage of bone defect healing, lactate accumulates and contributes to increasing NOD1 expression by stabilising HIF1α that in turn triggers a calcium influx, which ultimately polarises macrophages towards the M1 phenotype and accelerates vascularisation of endothelial cells.
Lulu Liu   +10 more
wiley   +1 more source

eNOS-dependent antisenscence effect of a calcium channel blocker in human endothelial cells. [PDF]

open access: yesPLoS ONE, 2014
Senescence of vascular endothelial cells is an important contributor to the pathogenesis of age-associated vascular disorders such as atherosclerosis. We investigated the effects of antihypertensive agents on high glucose-induced cellular senescence in ...
Toshio Hayashi   +6 more
doaj   +1 more source

Cryptococcid Sweet Syndrome in the Setting of Hydralazine‐Induced ANCA Vasculitis: A Case Report

open access: yesJournal of Cutaneous Pathology, EarlyView.
ABSTRACT Acute febrile neutrophilic dermatosis, also known as Sweet syndrome, is an inflammatory skin condition characterized by the rapid onset of painful, erythematous plaques or nodules with neutrophilic infiltrate on histology. Rarely, acellular bodies surrounded by vacuolated spaces have been noted within the neutrophilic infiltrate, mimicking ...
Jenna Vroman   +4 more
wiley   +1 more source

Reasons for patient reluctance to take preventive medications for migraine: Results of the OVERCOME (US) study

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background This study was undertaken to evaluate patient reasons for nonadoption of migraine‐preventive medications. Despite clear recommendations and eligibility criteria for migraine‐preventive treatment by the American Headache Society and the availability of these treatments, many people with migraine are not taking appropriate ...
Jessica Ailani   +9 more
wiley   +1 more source

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