Results 51 to 60 of about 59,868 (281)

The Type III Secretion System (T3SS) of Escherichia Coli Promotes Atherosclerosis in Type 2 Diabetes Mellitus

Advanced Science, EarlyView.
Large‐scale studies indicate a strong relationship between the gut microbiome, type 2 diabetes mellitus (T2DM), and atherosclerotic cardiovascular disease (ASCVD). Here, a higher abundance of the type III secretion system (T3SS) virulence factors of Enterobacteriaceae/Escherichia‐Shigella in patients with T2DM‐related‐ASCVD, which correlates with their
Yao‐Yuan Zhang, Song‐Tao Chen, Gang Chen, Le Zhou, Guo‐Liang Zhou, Xin‐Yuan Yu, Long Yuan, Wei‐Qian Deng, Zhen‐Bo Wang, Jing Li, Yi‐Fu Tu, Da‐Wei Zhang, Yuan li, Abdul Sammad, Xiao Zhu, Kai Yin   +15 more
wiley   +1 more source

Nifedipine and indomethacin in preventing preterm labor under 32 gestational weeks

Gülhane Tıp Dergisi, 2022
Aims:This study compared nifedipine and indomethacin treatments, commonly used tocolytic agents, in terms of efficacy and maternal side effects.Methods:This retrospective study included pregnant women spontaneous preterm labor between 24 and 32 weeks of ...
Gülşah Dağdeviren, Münevver Aksoy, Özge Yücel Çelik, Ayşe Keleş, Şevki Çelen, Ali Turhan Çağlar   +5 more
doaj   +1 more source

Plateau hypoxia attenuates the metabolic activity of intestinal flora to enhance the bioavailability of nifedipine

Drug Delivery, 2018
Nifedipine is completely absorbed by the gastrointestinal tract and its pharmacokinetics and metabolism may be influenced by microorganisms. If gut microbes are involved in the metabolism of nifedipine, plateau hypoxia may regulate the bioavailability ...
Juanhong Zhang, Yuyan Chen, Yuemei Sun, Rong Wang, Junmin Zhang, Zhengping Jia   +5 more
doaj   +1 more source

Things We Do for No Reason: Failing to consider primary aldosteronism in the initial evaluation of hypertension, hypertensive urgency, and hypertensive emergency

Journal of Hospital Medicine, EarlyView.
Abstract Hypertension is frequently treated as essential hypertension. However, secondary causes of hypertension should be considered, because distinct treatments are used for different causes of hypertension. Primary aldosteronism is considered a candidate for the most common cause of secondary hypertension.
Michael C. Shih, Tessa R. Lavorgna, Prerna Dogra, Christina N. Hirner, Kristen Payne   +4 more
wiley   +1 more source

Nifedipine-Induced Changes in the Electrohysterogram of Preterm Contractions: Feasibility in Clinical Practice

Obstetrics and Gynecology International, 2010
Objective. Evaluating changes in the power spectral density (PSD) peak frequency of the electrohysterogram (EHG) caused by nifedipine in women with preterm contractions. Methods.
Maartje P. G. C. Vinken, C. Rabotti, M. Mischi, J. O. E. H. van Laar, S. G. Oei   +4 more
doaj   +1 more source

Oral nifedipine may be a preferential option for treating acute severe hypertension during pregnancy: a meta-analysis

Hypertension in Pregnancy, 2023
Aim To compare oral nifedipine and intravenous labetalol in the treatment of acute severe hypertension in pregnancy (SHP). Methods The primary outcomes were the required time to achieve target blood pressure (RTATBP), systolic blood pressure (SBP) and ...
Minghui Ou, Futao Zhang, Shichao Cui, Shibo Zhao, Yan Yu   +4 more
doaj   +1 more source

Electrophysiological and arrhythmogenic effects of 5-hydroxytryptamine on human atrial cells are reduced in atrial fibrillation [PDF]

, 2007
5-Hydroxytryptamine (5-HT) is proarrhythmic in atrial cells from patients in sinus rhythm (SR) via activation of 5-HT₄ receptors, but its effects in atrial cells from patients with atrial fibrillation (AF) are unknown.
Andrew C. Rankin, Antony J. Workman, Bosch, Brattelid, Brundel, Castro, Christ, Davide Pau, Di Scala, Dobrev, Dobrev, Eglen, Grammer, Hegde, Jahnel, Kathleen A. Kane, Kaumann, Kaumann, Kaumann, Kaumann, Kilts, LeMessurier, Levy, Lonardo, Moe, Ouadid, Pau, Pau, Pindon, Redpath, Sanders, Schotten, Skasa, Sun, Van Wagoner, Van Wagoner, Van Wagoner, Wangemann, Wettwer, Workman, Workman, World Medical Association, Yusuf, Zerkowski, Zicha   +44 more
core   +2 more sources

Nifedipine for primary dysmenorrhoea

Cochrane Database of Systematic Reviews, 2017
Dysmenorrhoea (period pain) is a common condition with a substantial impact on the well-being and productivity of women. Primary dysmenorrhoea is defined as recurrent, cramping pelvic pain that occurs with periods, in the presence of a normal uterus, ovaries and fallopian tubes.
Rachel A Earl, Rosalie M Grivell
openaire   +3 more sources

Tetramethylenedisulfotetramine alters Ca²⁺ dynamics in cultured hippocampal neurons: mitigation by NMDA receptor blockade and GABA(A) receptor-positive modulation. [PDF]

, 2012
Tetramethylenedisulfotetramine (TETS) is a potent convulsant that is considered a chemical threat agent. We characterized TETS as an activator of spontaneous Ca²⁺ oscillations and electrical burst discharges in mouse hippocampal neuronal cultures at 13 ...
Cao, Zhengyu, Hammock, Bruce D, Lein, Pamela J, McCoy, Mark, Pessah, Isaac N, Rogawski, Michael A   +5 more
core   +2 more sources

Nifedipine treatment reduces resting calcium concentration, oxidative and apoptotic gene expression, and improves muscle function in dystrophic mdx mice. [PDF]

PLoS ONE, 2013
Duchenne Muscular Dystrophy (DMD) is a recessive X-linked genetic disease, caused by mutations in the gene encoding dystrophin. DMD is characterized in humans and in mdx mice by a severe and progressive destruction of muscle fibers, inflammation ...
Francisco Altamirano, Denisse Valladares, Carlos Henríquez-Olguín, Mariana Casas, Jose R López, Paul D Allen, Enrique Jaimovich   +6 more
doaj   +1 more source