Results 61 to 70 of about 59,868 (281)

Pharmacokinetic Herb-Drug Interactions: Insight into Mechanisms and Consequences [PDF]

open access: yes, 2015
Herbal medicines are currently in high demand, and their popularity is steadily increasing. Because of their perceived effectiveness, fewer side effects and relatively low cost, they are being used for the management of numerous medical conditions ...
Horie, Toshiharu   +3 more
core   +1 more source

Investigating the Mechanism of Conditioning Versus Postoperative Electrical Stimulation to Enhance Nerve Regeneration: One Therapy, Two Distinct Effects

open access: yesMuscle &Nerve, EarlyView.
ABSTRACT Regeneration after peripheral nerve injury is often insufficient for functional recovery. Postoperative electrical stimulation (PES) following injury and repair significantly improves clinical outcomes; recently, conditioning electrical stimulation (CES), delivered before nerve injury, has been introduced as a candidate for clinical ...
Paige B. Hardy   +4 more
wiley   +1 more source

Phase 1 repolarization rate defines Ca2+ dynamics and contractility on intact mouse hearts. [PDF]

open access: yes, 2019
In the heart, Ca2+ influx through L-type Ca2+ channels triggers Ca2+ release from the sarcoplasmic reticulum. In most mammals, this influx occurs during the ventricular action potential (AP) plateau phase 2.
Escobar, Ariel L   +4 more
core   +1 more source

The Antihypertensive Drug Nifedipine Modulates the Metabolism of Chondrocytes and Human Bone Marrow-Derived Mesenchymal Stem Cells

open access: yesFrontiers in Endocrinology, 2019
Aging is associated with the development of various chronic diseases, in which both cardiovascular disorders and osteoarthritis are dominant. Currently, there is no effective treatment for osteoarthritis, whereas hypertension is often treated with L-type
Ilona Uzieliene   +11 more
doaj   +1 more source

Effects of Platelet-Activating Factor on Brain Microvascular Endothelial Cells. [PDF]

open access: yes, 2018
Platelet-activating factor (PAF) is a potent phospholipid mediator that exerts various pathophysiological effects by interacting with a G protein-coupled receptor.
Abood, Mary E.   +4 more
core   +1 more source

Osteoblast interactions within a biomimetic apatite microenvironment. [PDF]

open access: yes, 2011
Numerous reports have shown that accelerated apatites can mediate osteoblastic differentiation in vitro and bone formation in vivo. However, how cells interact within the apatite microenvironment remains largely unclear, despite the vast literature ...
Arakawa, Christopher K   +3 more
core   +3 more sources

Polyphenols for the Prevention or Management of Preeclampsia: A Systematic Review and Meta‐Analysis

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objectives To evaluate the effects of polyphenol‐containing products during pregnancy on preeclampsia‐related maternal and neonatal outcomes. Design Systematic review and meta‐analysis. Setting Nine databases and one trial registry, from inception to August 11th, 2023.
Phi‐Yen Nguyen   +7 more
wiley   +1 more source

The Effect of Topical Nifedipine in Treatment of Chronic Anal Fissure [PDF]

open access: yesActa Medica Iranica, 2010
Chronic anal fissure is the most common cause of anal pain associated with internal anal sphincter hypertonia. Reduction of hypertonocity is a special treatment for fissure healing.
Farzaneh Golfam   +3 more
doaj   +1 more source

Crystal growth rates and molecular dynamics of nifedipine [PDF]

open access: yes, 2013
The unusually fast crystallization of the organic compound nifedipine has been investigated in detail using different solutions as precursors for the formation of the initial glassy nifedipine films.
Emmerling, Franziska   +6 more
core   +1 more source

Protein binding of nifedipine

open access: yesJournal of Pharmacy and Pharmacology, 1986
Abstract The protein binding of nifedipine in concentrations up to 1200 ng ml−1 has been measured in serum, pure human albumin solution and pure human α1-acid glycoprotein (AAG) solutions by ultrafiltration. The drug was extensively bound in serum from four healthy volunteers with a mean (±s.d.) fraction bound of 0.992 ± 0.008.
Lawrence J. Lesko, J Otto
openaire   +3 more sources

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