Results 71 to 80 of about 37,594 (237)
Promotion of cutaneous penetration of nifedipine for nanoemulsion
Brazilian Journal of Pharmaceutical Sciences, 2017 This article reports the development and characterization of a nanoemulsion (NE) able to improve the cutaneous penetration of nifedipine. NE with nifedipine was development and characterized, presenting droplet size of 20 nm with low polydispersity index
Paula de Oliveira Arantes +7 more
doaj +1 more source
Experimental Physiology, EarlyView.Abstract Poor maternal nutrition and excessive gestational weight gain predict future development of obesity in offspring. Preclinically, maternal obesity induced by a high‐fat, high‐sugar diet (HFHSD) induces hyperphagia and obesity in offspring. We hypothesized that this might, in part, reflect reduced peripheral gastric vagal afferent (GVA) satiety ...
Georgia S. Clarke +7 more
wiley +1 more source
The antihypertensive effect of orally administered nifedipine‐loaded nanoparticles in spontaneously hypertensive rats [PDF]
, 1997 Young Tae Kim +5 more
openalex +1 more source
Experimental Physiology, EarlyView.Abstract Ageing is a risk factor for cardiovascular and neurodegenerative diseases. The myogenic response in resistance arteries is responsible for basal (myogenic) tone and blood flow autoregulation. G‐protein‐coupled receptors and G12/RhoA/Rho kinase are implicated in myogenic tone (MT), and we aimed to clarify their role in pressure sensing and ...
Gry Freja Skovsted +11 more
wiley +1 more source
Experimental Physiology, EarlyView.Abstract Chronic visceral pain is a key symptom of irritable bowel syndrome. Modulation of voltage‐gated calcium and potassium channels by G protein‐coupled receptors plays a key role in dampening nociceptive transmission. Both baclofen and the analgesic peptide α‐conotoxin Vc1.1 activate GABAB receptors (GABABR), resulting in inhibition of CaV2.2 and ...
Mariana Brizuela +4 more
wiley +1 more source
Soybean Isoflavones Eliminate Nifedipine-Induced Flushing of Tail Skin in Ovariectomized Mice
Journal of Pharmacological Sciences, 2004 Hot flushes are one of the most frequent symptoms in menopausal women. We investigated effect of soybean isoflavones (Soyaflavone HG) on nifedipine-induced flushing in ovariectomized mice.
Mamiko Kai +5 more
doaj +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Cells and conductances contributing to spontaneous activity in the lower urinary tract. Bladder and urethra exhibit spontaneous contractions at both cellular and tissue levels. Both detrusor and urethral smooth muscle cells display activity that is regular and rhythmic.
Bernard T. Drumm +3 more
wiley +1 more source
Nifedipine improves blood flow and oxygen supply, but not steady-state oxygenation of tumours in perfusion pressure-controlled isolated limb perfusion [PDF]
, 2002 Oliver Thews +4 more
openalex +1 more source
A Comparative Study of the Effectiveness of Transdermal Nitroglycerine Patches and Oral Nifedipine in Prolongation of Pregnancy in Women With Preterm Labour [PDF]
, 2023 Nidhi Goyal +3 more
openalex +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend In this study, we use human‐induced pluripotent stem cell‐derived cardiomyocyte (hiPSC‐CM) experiments and computational modelling to identify the mechanism of action of drug compounds. In the hiPSC‐CM experiments, optical measurements of cell collections are recorded in the baseline case and after drug exposure.
Karoline Horgmo Jæger +4 more
wiley +1 more source