Modulation of a sustained calcium current by intracellular pH in horizontal cells of fish retina. [PDF]
A sustained high voltage-activated (HVA), nifedipine- and cadmium-sensitive calcium current and a sustained calcium action potential (AP) were recorded from horizontal cells isolated from catfish retina.
Copenhagen, DR, Dixon, DB, Takahashi, K
core
The contribution of ionic currents to changes in refractoriness of human atrial myocytes associated with chronic atrial fibrillation [PDF]
<b>Objective:</b> To investigate changes in human atrial single cell functional electrophysiological properties associated with chronic atrial fibrillation (AF), and the contribution to these of accompanying ion current changes.
Kane, K.A., Rankin, A.C., Workman, A.J.
core +1 more source
Fetoscopic Laser Ablation of Type II Vasa Previa—Case Report and Systematic Review
ABSTRACT Vasa previa is a rare but potentially fatal obstetric condition in which fetal vessels traverse the internal cervical os without the protection of placental tissue or Wharton's jelly, making them highly vulnerable to rupture during labor or spontaneous membrane rupture. This can result in rapid fetal exsanguination and death.
Rodrigo Ruano +5 more
wiley +1 more source
TREATMENT OF GINGIVAL HYPERPLASIA INDUCED BY NIFEDIPINE
The use of Nifedipine as cardiovascular therapy is proven to be the cause of gingival hyperplasia. The objective of this present case is to report the gingival hyperplasia induced by nifedipine, and the best management suggested.
Mitayani Restuning Kusumarini +1 more
doaj +1 more source
The prion protein constitutively controls neuronal store-operated ca2+ entry through Fyn Kinase [PDF]
The prion protein (PrPC) is a cell surface glycoprotein mainly expressed in neurons, whose misfolded isoforms generate the prion responsible for incurable neurodegenerative disorders.
Agnese eDe Mario +8 more
core +4 more sources
Abstract The protein binding of nifedipine in concentrations up to 1200 ng ml−1 has been measured in serum, pure human albumin solution and pure human α1-acid glycoprotein (AAG) solutions by ultrafiltration. The drug was extensively bound in serum from four healthy volunteers with a mean (±s.d.) fraction bound of 0.992 ± 0.008.
Lawrence J. Lesko, J Otto
openaire +3 more sources
High-Dose Calcium Channel Blockade in PH: Old Lessons, New Tools. [PDF]
ABSTRACT This letter to the editor revisits the origins of high‐dose calcium channel blocker use in pulmonary arterial hypertension (PAH) in light of bedside vasoreactivity testing, reaffirming its present‐day relevance for a selected subgroup. Integrating historical insights with modern tools, the authors highlight: the “responder” phenotype as an ...
Pagnoni G, Vicenzi A, Coppi F.
europepmc +2 more sources
Gene Expression in Experimental Aortic Coarctation and Repair: Candidate Genes for Therapeutic Intervention? [PDF]
Coarctation of the aorta (CoA) is a constriction of the proximal descending thoracic aorta and is one of the most common congenital cardiovascular defects.
Bozdag, Serdar +5 more
core +3 more sources
ABSTRACT Background Hypertensive disorders of pregnancy are a leading cause of pregnancy‐related morbidity and mortality. Timely treatment of a hypertensive emergency has the potential to reduce preeclampsia‐related morbidity and mortality. Objective To evaluate the impact of quality improvement and patient safety initiatives on timely treatment of ...
Towana D. Sims +5 more
wiley +1 more source
Rhabdomyolysis Induced by Irbesartan-Hydrochlorothiazide in an Elderly Patient. [PDF]
ABSTRACT A 90‐year‐old male with hypertension and diabetes presented with acute limb weakness and dizziness. Laboratory tests revealed severe hyponatremia (Na+ 111.6 mmol/L) and rhabdomyolysis (CK 1771 U/L), which occurred after the recent initiation of irbesartan‐hydrochlorothiazide for edema.
Yang W, Luo J, Chen W, Peng B.
europepmc +2 more sources

