Results 71 to 80 of about 59,868 (281)
Characterisation of Anti-Arrhythmic Drug Effects on Cardiac Electrophysiology using Physics-Informed Neural Networks [PDF]
The ability to accurately infer cardiac electrophysiological (EP) properties is key to improving arrhythmia diagnosis and treatment. In this work, we developed a physics-informed neural networks (PINNs) framework to predict how different myocardial EP parameters are modulated by anti-arrhythmic drugs.
arxiv +1 more source
Journal of Nepal Medical Association, 2017 Introduction: Anal fissure is an ischemic ulcer caused by combination of spasm of internal anal sphincter and poor blood supply to the posterior midline of anal canal.
Suman Kumar Shrestha +3 more
doaj +1 more source
Contribution of baicalin on the plasma protein binding displacement and CYP3A activity inhibition to the pharmacokinetic changes of nifedipine in rats in vivo and in vitro. [PDF]
PLoS ONE, 2014 Baicalin purified from the root of Radix scutellariae is widely used in clinical practices. This study aimed to evaluate the effect of baicalin on the pharmacokinetics of nifedipine, a CYP3A probe substrate, in rats in vivo and in vitro. In a randomised,
Zhen-Yu Cheng +5 more
doaj +1 more source
SAFETY EVALUATION OF STATIN IN YOGYAKARTA, INDONESIA [PDF]
, 2009 Background : The 3-hydroxy-3-methylglutaryl-coenzyme (HMG-Co-A) reductase inhibitors, also known as statins, are the most effective class of drugs for lowering serum Low-Density Lipoprotein cholesterol (LDL-c)concentrations.
Anni, Anni +3 more
core
British Journal of Clinical Pharmacology, EarlyView.Aerospace medicine required controlled terrestrial models to investigate influences of altered atmosphere conditions, such as hypoxia, on human health and performance. These models could potentially be expanded to encompass disease conditions or treatment targets regulated through hypoxia or hypercapnia.
Titiaan E. Post +4 more
wiley +1 more source
Рациональная фармакотерапия в кардиологии, 2015 Aim. To compare information value of antihypertensive effect equability parameters for two drug formulations of nifedipine: long-acting one (nifedipine-XL) and short-acting one (nifedipine-sa).Material and methods. 147 patients with arterial hypertension
V. M. Gorbunov +2 more
doaj +1 more source
Two dimensional electrophysiological characterization of human pluripotent stem cell-derived cardiomyocyte system. [PDF]
, 2017 Stem cell-derived cardiomyocytes provide a promising tool for human developmental biology, regenerative therapies, disease modeling, and drug discovery.
Gimzewski, James K +7 more
core +2 more sources
Effect of Gastric Fluid Volume on the in Vitro Dissolution and in Vivo Absorption of BCS Class II Drugs: A Case Study with Nifedipine [PDF]
, 2016 Nifedipine is a BCS Class II drug used for treatment of hypertension and preterm labor. Large inter-patient variability in nifedipine absorption results in variable exposure among different patients.
Fadda, Hala M. +3 more
core +1 more source
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Papillary thyroid cancer (PTC) is a general thyroid cancer subtype; however, PTC is associated with metastasis or recurrence via anti‐cancer drug resistance, rendering it practically incurable. Therefore, effective and reliable clinical approaches are urgently required.
Seok‐Mo Kim +5 more
wiley +1 more source
TREATMENT OF GINGIVAL HYPERPLASIA INDUCED BY NIFEDIPINE
Journal of Dentistry Indonesia, 2015 The use of Nifedipine as cardiovascular therapy is proven to be the cause of gingival hyperplasia. The objective of this present case is to report the gingival hyperplasia induced by nifedipine, and the best management suggested.
Mitayani Restuning Kusumarini +1 more
doaj +1 more source