Results 21 to 30 of about 437,208 (310)

Protein kinases in induction of type II nitric oxide synthase

Japanese Journal of Pharmacology, 1996
Hideki Moritoki, Tetsuhiro Hisayama, Wataru Kondoh, Kann Kida   +3 more
openalex   +3 more sources

INDUCIBLE NITRIC OXIDE SYNTHASE EXPRESSION AND NUCLEAR FACTOR-κB ACTIVATION IN ALVEOLAR TYPE II CELLS IN LUNG INJURY

Experimental Lung Research, 2001
Alveolar type II cells (type II cells) play a crucial role in the progression and repair of lung inflammation and injury. We investigated whether inducible nitric oxide synthase (iNOS) was expressed and nuclear factor-kappaB (NF-kappaB) was activated in type II cells in lung injury.
Hirohisa Toga, Takeyasu Tobe, Yoshimichi Ueda, Guanhu Yang, Kazuhiro Osanai, Masanobu Ishigaki, Hiroshi Okazaki, Shogo Katsuda, Keiji Takahashi, Nobuo Ohya   +9 more
openalex   +4 more sources

INVOLVEMENT OF NF-κB ACTIVATION IN THE INDUCTION OF TYPE II NITRIC OXIDE SYNTHASE HUMAN GLIOLASTOMA CELLS

Biomedical Research, 1998
Mikiro Kobayashi, Tomoko Suzuki, Iwao Suzuki, Shyh‐Yuh Liou, Yasuhiro Hashimoto, Kouichi Hashimoto   +5 more
openalex   +4 more sources

Inhibition of nitric oxide production of activated mice peritoneal macrophages is independent of the Toxoplasma gondii strain [PDF]

Memorias do Instituto Oswaldo Cruz, 2021
BACKGROUND Toxoplasma gondii causes toxoplasmosis and is controlled by activated macrophages. However, infection of macrophages by tachyzoites induces TGF-β signaling (TGF-s) inhibiting nitric oxide (NO) production.
João Cláudio Damasceno-Sá, Fernanda Silva de Souza, Thiago Alves Teixeira dos Santos, Fábio Conceição de Oliveira, Maria de Fátima Sarro da Silva, Raul Ramos Furtado Dias, Wanderley de Souza, Andrea Cristina Veto Arnholdt, Sergio Henrique Seabra, Renato Augusto DaMatta   +9 more
doaj   +1 more source

Parkia speciosa Hassk. Empty Pod Extract Alleviates Angiotensin II-Induced Cardiomyocyte Hypertrophy in H9c2 Cells by Modulating the Ang II/ROS/NO Axis and MAPK Pathway

Frontiers in Pharmacology, 2021
Cardiac hypertrophy is characteristic of heart failure in patients who have experienced cardiac remodeling. Many medicinal plants, including Parkia speciosa Hassk., have documented cardioprotective effects against such pathologies.
Hawa Nordin Siti, Hawa Nordin Siti, Juriyati Jalil, Ahmad Yusof Asmadi, Yusof Kamisah, Yusof Kamisah   +5 more
doaj   +1 more source

LIT01-196, a Metabolically Stable Apelin-17 Analog, Normalizes Blood Pressure in Hypertensive DOCA-Salt Rats via a NO Synthase-dependent Mechanism [PDF]

Frontiers in Pharmacology, Frontiers, 2021, 12, 2022
Apelin is a neuro-vasoactive peptide that plays a major role in the control of cardiovascular functions and water balance, but has an in-vivo half-life in the minute range, limiting its therapeutic use. We previously developed LIT01-196, a systemically active metabolically stable apelin-17 analog, produced by chemical addition of a fluorocarbon chain ...
arxiv   +1 more source

Vasoconstrictor and Pressor Effects of Des-Aspartate-Angiotensin I in Rat

Biomedicines, 2022
This study investigated the vasoactive effects of des-aspartate-angiotensin-I (DAA-I) in male Wistar rats on whole body vascular bed, isolated perfused kidneys, and aortic rings.
Rosemary Wangensteen, Manuel Gómez-Guzmán, Inmaculada Banegas, Isabel Rodríguez-Gómez, Rosario Jiménez, Juan Duarte, Joaquín García-Estañ, Félix Vargas   +7 more
doaj   +1 more source

The Antitumoral Effect of Paris Saponin II on Head and Neck Squamous Cell Carcinomas Mediated via the Nitric Oxide Metabolic Pathway

Frontiers in Cell and Developmental Biology, 2022
Paris saponin has shown great therapeutic value in cancer therapy. We used isolated Paris saponin II (PSII), an active component of Paris saponin, and demonstrated its antitumor effect on human head and neck squamous cell carcinoma cell lines ...
Wenwen Qi, Wenwen Qi, Fangyuan Zhu, Min Wang, Zhenxiao Teng, Zhenxiao Teng, Runtong Xu, Yue Xi, Qiu Meng, Xinhao Wu, Xinhao Wu, Hui Zhao, Min Ma, Xiaozhi Hou, Baowei Wang, Xiaoming Li, Chengcheng Liu, Xiang Zhang, Fenglei Xu, Ming Xia, Ming Xia   +20 more
doaj   +1 more source

Covalent Functionalization of HiPco Single-Walled Carbon Nanotubes: Differences in the Oxidizing Action of H2SO4 and HNO3 during a Soft Oxidation Process [PDF]

ChemPhysChem, Wiley-VCH Verlag, 2015, 16 (12), pp.2692-2701, 2021
The results of a study on the evolution of HiPco single-walled carbon nanotubes during the oxidizing action of H2SO4 and HNO3 are presented. The process conditions used have been chosen so as to avoid any significant damage to the nanotube structure. The type and level of functionalization, the location of the grafted functions on the surface of the ...
arxiv   +1 more source

The kinetics and regulation of the induction of type II nitric oxide synthase and nitric oxide in human fetal glial cell cultures [PDF]

Molecular Psychiatry, 1997
Our understanding of how human glial cells are induced to produce nitric oxide and how the production is regulated may allow us to better design therapeutic strategies for treating inflammatory diseases of the central nervous system in man. Cultures of human fetal astrocytes and microglia produce inducible nitric oxide synthase and nitric oxide in ...
M Ding, J E Merrill
openaire   +3 more sources