Results 11 to 20 of about 175,774 (310)

Nitric Oxide Differentially Regulates Induction of Type II Nitric Oxide Synthase in Rat Vascular Smooth Muscle Cells Versus Macrophages [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2001
Abstract —We studied effects of nitric oxide (NO) released by different NO donors on induction of inducible NO synthase (iNOS) in rat aortic smooth muscle cells (RASMC) and rat macrophage cell line NR8383. iNOS protein expression induced by a CM (interleukin-1β 250 U/mL, interferon-γ 150 U/mL, and tumor necrosis factor-α 150 U ...
H, Zhang, C, Snead, J D, Catravas
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Effects of Ovine Monocyte-Derived Macrophage Infection by Recently Isolated Toxoplasma gondii Strains Showing Different Phenotypic Traits

Animals, 2022
Ovine toxoplasmosis is one the most relevant reproductive diseases in sheep. The genetic variability among different Toxoplasma gondii isolates is known to be related to different degrees of virulence in mice and humans, but little is known regarding its
Raquel Vallejo, Julio Benavides, Noive Arteche-Villasol, Mercedes Fernández-Escobar, María Del Carmen Ferreras, Valentín Pérez, Daniel Gutiérrez-Expósito   +6 more
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Nitric oxide and L-type calcium channel influences the changes in arterial blood pressure and heart rate induced by central angiotesin II

Behavioral and Brain Functions, 2008
We study the voltage dependent calcium channels and nitric oxide involvement in angiotensin II-induced pressor effect. The antipressor action of L-Type calcium channel antagonist, nifedipine, has been studied when it was injected into the third ventricle
Guarda Ismael FMS, Saad Wilson A, Camargo Luiz AA, Santos Talmir AFB   +3 more
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Distinct Dimer Interaction and Regulation in Nitric-oxide Synthase Types I, II, and III [PDF]

Journal of Biological Chemistry, 2002
Homodimer formation activates all nitric-oxide synthases (NOSs). It involves the interaction between two oxygenase domains (NOSoxy) that each bind heme and (6R)-tetrahydrobiopterin (H4B) and catalyze NO synthesis from L-Arg. Here we compared three NOSoxy isozymes regarding dimer strength, interface composition, and the ability of L-Arg and H4B to ...
Koustubh, Panda, Robin J, Rosenfeld, Sanjay, Ghosh, Abigail L, Meade, Elizabeth D, Getzoff, Dennis J, Stuehr   +5 more
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Tonic and phasic nitric oxide signals in hippocampal long-term potentiation [PDF]

, 2006
Nitric oxide ( NO) participates in long-term potentiation (LTP) and other forms of synaptic plasticity in many different brain areas but where it comes from and how it acts remain controversial.
Garthwaite, J, Hopper, RA
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Effect of Icariside II and Metformin on Penile Erectile Function, Histological Structure, Mitochondrial Autophagy, Glucose-Lipid Metabolism, Angiotensin II and Sex Hormone in Type 2 Diabetic Rats With Erectile Dysfunction

Sexual Medicine, 2020
Introduction: Type 2 diabetes mellitus erectile dysfunction (T2DMED) is one of the common complications of type 2 diabetes mellitus (T2DM). Icariside II (ICA II), a flavonoid derived from Epimedium, has been shown to improve erectile function in T2DMED ...
Jian Zhang, MD, Shuang Li, BS, Shiqing Zhang, MS, Yonghui Wang, BS, Shipeng Jin, BS, Chunli Zhao, MS, Wenzeng Yang, MD, Yuexin Liu, MS, Guangqi Kong, MS   +8 more
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Angiotensin II Type 2 Receptor Decreases Transforming Growth Factor-β Type II Receptor Expression and Function in Human Renal Proximal Tubule Cells. [PDF]

PLoS ONE, 2016
Transforming growth factor-β (TGF-β), via its receptors, induces epithelial-mesenchymal transition (EMT) and plays an important role in the development of renal tubulointersitial fibrosis.
Hui-Lin Guo, Xiao-Hui Liao, Qi Liu, Ling Zhang   +3 more
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Impaired endothelial function of the retinal vasculature in hypertensive patients [PDF]

, 2004
<p><b>Background and Purpose:</b> Arterial hypertension constitutes a central factor in the pathogenesis of stroke. We examined endothelial function of the retinal vasculature as a model of the cerebral circulation.</p> <p ...
Delles, C., Harazny, J., Hilgers, K.F., Michelson, G., Oehmer, S., Schmieder, R.E.   +5 more
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AT1 Receptor Mediated Hypertensive Response to Ang II in the Nucleus Tractus Solitarii of Normotensive Rats Involves NO Dependent Local GABA Release

Frontiers in Pharmacology, 2019
AimIt is well-established that angiotensin II exerts a dampening effect on the baroreflex within the nucleus tractus solitarii (NTS), the principal brainstem site for termination of baroreceptor afferents and which is densely populated with gamma ...
Laura Légat, Laura Légat, Laura Légat, Ilse Smolders, Alain G. Dupont, Alain G. Dupont, Alain G. Dupont   +6 more
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Endothelial Nitric Oxide Synthase Gene Polymorphism (G894T) and Diabetes Mellitus (Type II) among South Indians [PDF]

Oxidative Medicine and Cellular Longevity, 2011
The objective of the study is to find out whether the endothelial nitric oxide synthase (eNOS) G894T single-nucleotide polymorphism is associated with type 2 diabetes mellitus in South Indian (Tamil) population. A total number of 260 subjects comprising 100 type 2 diabetic mellitus patients and 160 healthy individuals with no documented history of ...
Angeline, T., Krithiga, H. R., Isabel, W., Asirvatham, A. J., Poornima, A.   +4 more
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