Results 11 to 20 of about 93,042 (311)

Endothelial Nitric Oxide Synthase Gene Polymorphism (G894T) and Diabetes Mellitus (Type II) among South Indians [PDF]

Oxidative Medicine and Cellular Longevity, 2011
The objective of the study is to find out whether the endothelial nitric oxide synthase (eNOS) G894T single-nucleotide polymorphism is associated with type 2 diabetes mellitus in South Indian (Tamil) population. A total number of 260 subjects comprising 100 type 2 diabetic mellitus patients and 160 healthy individuals with no documented history of ...
Angeline, T., Krithiga, H. R., Isabel, W., Asirvatham, A. J., Poornima, A.   +4 more
openaire   +4 more sources

Signalling pathway involved in nitric oxide synthase type II activation in chondrocytes: synergistic effect of leptin with interleukin-1 [PDF]

Arthritis Research & Therapy, 2005
AbstractThe objective of the present study was to investigate the effect of leptin, alone or in combination with IL-1, on nitric oxide synthase (NOS) type II activity in vitro in human primary chondrocytes, in the mouse chondrogenic ATDC5 cell line, and in mature and hypertrophic ATDC5 differentiated chondrocytes. For completeness, we also investigated
Otero, Miguel, Lago, Rocío, Lago, Francisca, Reino, Juan Jesús Gomez, Gualillo, Oreste   +4 more
openaire   +5 more sources

Effects of Ovine Monocyte-Derived Macrophage Infection by Recently Isolated Toxoplasma gondii Strains Showing Different Phenotypic Traits

Animals, 2022
Ovine toxoplasmosis is one the most relevant reproductive diseases in sheep. The genetic variability among different Toxoplasma gondii isolates is known to be related to different degrees of virulence in mice and humans, but little is known regarding its
Raquel Vallejo, Julio Benavides, Noive Arteche-Villasol, Mercedes Fernández-Escobar, María Del Carmen Ferreras, Valentín Pérez, Daniel Gutiérrez-Expósito   +6 more
doaj   +1 more source

Nitric oxide and L-type calcium channel influences the changes in arterial blood pressure and heart rate induced by central angiotesin II

Behavioral and Brain Functions, 2008
We study the voltage dependent calcium channels and nitric oxide involvement in angiotensin II-induced pressor effect. The antipressor action of L-Type calcium channel antagonist, nifedipine, has been studied when it was injected into the third ventricle
Guarda Ismael FMS, Saad Wilson A, Camargo Luiz AA, Santos Talmir AFB   +3 more
doaj   +1 more source

Study of the Relation between Endothelial Nitric Oxide Synthase G894T Gene Variants and Occurrence of Type II Hepatorenal Syndrome [PDF]

Afro-Egyptian Journal of Infectious and Endemic Diseases, 2020
Background  and study aim: The progress of hepatorenal syndrome (HRS) in hepatic patients is not yet understood. Nitric oxide level, through its impact on haemodynamic circulation, may be engaged in the progress of the disease.
Hossam Mohammed, Safaa Tayel, Mostafa El Nimer, Naglaa Elabd   +3 more
doaj   +1 more source

Nitric Oxide Differentially Regulates Induction of Type II Nitric Oxide Synthase in Rat Vascular Smooth Muscle Cells Versus Macrophages [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2001
Abstract —We studied effects of nitric oxide (NO) released by different NO donors on induction of inducible NO synthase (iNOS) in rat aortic smooth muscle cells (RASMC) and rat macrophage cell line NR8383. iNOS protein expression induced by a CM (interleukin-1β 250 U/mL, interferon-γ 150 U/mL, and tumor necrosis factor-α 150 U ...
H, Zhang, C, Snead, J D, Catravas
openaire   +2 more sources

Effect of Icariside II and Metformin on Penile Erectile Function, Histological Structure, Mitochondrial Autophagy, Glucose-Lipid Metabolism, Angiotensin II and Sex Hormone in Type 2 Diabetic Rats With Erectile Dysfunction

Sexual Medicine, 2020
Introduction: Type 2 diabetes mellitus erectile dysfunction (T2DMED) is one of the common complications of type 2 diabetes mellitus (T2DM). Icariside II (ICA II), a flavonoid derived from Epimedium, has been shown to improve erectile function in T2DMED ...
Jian Zhang, MD, Shuang Li, BS, Shiqing Zhang, MS, Yonghui Wang, BS, Shipeng Jin, BS, Chunli Zhao, MS, Wenzeng Yang, MD, Yuexin Liu, MS, Guangqi Kong, MS   +8 more
doaj   +1 more source

Angiotensin II Type 2 Receptor Decreases Transforming Growth Factor-β Type II Receptor Expression and Function in Human Renal Proximal Tubule Cells. [PDF]

PLoS ONE, 2016
Transforming growth factor-β (TGF-β), via its receptors, induces epithelial-mesenchymal transition (EMT) and plays an important role in the development of renal tubulointersitial fibrosis.
Hui-Lin Guo, Xiao-Hui Liao, Qi Liu, Ling Zhang   +3 more
doaj   +1 more source

Effects of Cinnamomum cassia extract on oxidative stress, immunreactivity of iNOS and impaired thoracic aortic reactivity induced by type II diabetes in rats

Brazilian Journal of Pharmaceutical Sciences, 2018
Type II diabetes is known to cause neuropathy, nephropathy and retinopathy. However, cardiovascular disorders associated with diabetes have been ignored.
Gözde Atila Uslu, Volkan Gelen, Hamit Uslu, Hasan Özen   +3 more
doaj   +1 more source

Release and elementary mechanisms of nitric oxide in hair cells [PDF]

, 2010
The enzyme nitric oxide (NO) synthase, that produces the signaling molecule NO, has been identified in several cell types in the inner ear. However, it is unclear whether a measurable quantity of NO is released in the inner ear to confer specific ...
Song, Haitao, Smith, Peter J S, Yamoah, Ebenezer N, Lv, Ping, Eastwood, Emily, Yevgeniy, Petrov Y, Mu, Karen, Levic, Snezana, Wei, Dongguang, Zhu, Jun, Kim, Hyo Jeong, Choong-Ryoul, Sihn, Rodriguez-Contreras, Adrian   +12 more
core   +1 more source