Results 21 to 30 of about 1,819 (263)

Effects of Ovine Monocyte-Derived Macrophage Infection by Recently Isolated Toxoplasma gondii Strains Showing Different Phenotypic Traits

open access: yesAnimals, 2022
Ovine toxoplasmosis is one the most relevant reproductive diseases in sheep. The genetic variability among different Toxoplasma gondii isolates is known to be related to different degrees of virulence in mice and humans, but little is known regarding its
Raquel Vallejo   +6 more
doaj   +1 more source

Study of the Relation between Endothelial Nitric Oxide Synthase G894T Gene Variants and Occurrence of Type II Hepatorenal Syndrome [PDF]

open access: yesAfro-Egyptian Journal of Infectious and Endemic Diseases, 2020
Background  and study aim: The progress of hepatorenal syndrome (HRS) in hepatic patients is not yet understood. Nitric oxide level, through its impact on haemodynamic circulation, may be engaged in the progress of the disease.
Hossam Mohammed   +3 more
doaj   +1 more source

Octacalcium phosphate crystals directly stimulate expression of inducible nitric oxide synthase through p38 and JNK mitogen-activated protein kinases in articular chondrocytes [PDF]

open access: yes, 2005
Basic calcium phosphate (BCP) crystals, including hydroxyapatite, octacalcium phosphate (OCP) and carbonate-apatite, have been associated with severe osteoarthritis and several degenerative arthropathies.
Uzan, Benjamin   +3 more
core   +1 more source

Angiogenesis "in vitro" of the healthy mouse heart under hypoxia : the role of Angiotensin II and Nitric Oxide [PDF]

open access: yes, 2005
Angiogenesis is the process by which blood microvessels are formed from existing ones. Angiogenesis is required for development. It is also important for reducing myocardial hypoxia due to coronary and ischemic heart disease; in myocardial infarction ...
Munk, Veronica Cecilia
core   +1 more source

Abnormal modulation of cell protective systems in response to ischemic/reperfusion injury is important in the development of mouse sickle cell hepatopathy

open access: yesHaematologica, 2011
Background Sickle cell disease, a genetic red cell disorder inherited in an autosomal recessive manner, occurs throughout the world. Hepatic dysfunction and liver damage may be present in sickle cell disease, but the pathogenesis of these conditions is ...
Angela Siciliano   +10 more
doaj   +1 more source

Alamandine reduces leptin expression through the c-Src/p38 MAP kinase pathway in adipose tissue. [PDF]

open access: yesPLoS ONE, 2017
Obesity is associated with an increased risk of diabetes mellitus, hypertension, and renal dysfunction. Angiotensin 1-7 and alamandine are heptameric renin angiotensin system peptide hormones.
Tsuyoshi Uchiyama   +5 more
doaj   +1 more source

Nitric oxide modulates expression of extracellular matrix genes linked to fibrosis in kidney mesangial cells [PDF]

open access: yes, 2007
Mesangial cells are thought to be important mediators of glomerular inflammation and fibrosis. Studies have established a direct role for nitric oxide (NO) in the regulation of gene expression in mesangial cells.
Nelson, Peter J.   +4 more
core   +1 more source

Sex differences in angiotensin II- induced hypertension

open access: yesBrazilian Journal of Medical and Biological Research, 2007
Sex differences in the development of hypertension and cardiovascular disease have been described in humans and in animal models. In this paper we will review some of our studies which have as their emphasis the examination of the role of sex differences
B. Xue, A.K. Johnson, M. Hay
doaj   +1 more source

Malfunction of Vascular Control in Lifestyle-Related Diseases: Mechanisms Underlying Endothelial Dysfunction in the Insulin-Resistant State

open access: yesJournal of Pharmacological Sciences, 2004
It is tempting to speculate that increased vasoconstriction and loss of endothelium-dependent vasodilation might be etiological factors of elevated blood pressure in the insulin-resistant state.
Kazuya Shinozaki   +4 more
doaj   +1 more source

Impaired endothelial function of the retinal vasculature in hypertensive patients [PDF]

open access: yes, 2004
<p><b>Background and Purpose:</b> Arterial hypertension constitutes a central factor in the pathogenesis of stroke. We examined endothelial function of the retinal vasculature as a model of the cerebral circulation.</p> <p ...
Michelson, G.   +5 more
core   +1 more source

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