Alamandine reduces leptin expression through the c-Src/p38 MAP kinase pathway in adipose tissue. [PDF]
Obesity is associated with an increased risk of diabetes mellitus, hypertension, and renal dysfunction. Angiotensin 1-7 and alamandine are heptameric renin angiotensin system peptide hormones.
Tsuyoshi Uchiyama+5 more
doaj +1 more source
Sex differences in angiotensin II- induced hypertension
Sex differences in the development of hypertension and cardiovascular disease have been described in humans and in animal models. In this paper we will review some of our studies which have as their emphasis the examination of the role of sex differences
B. Xue, A.K. Johnson, M. Hay
doaj +1 more source
Doppler-free high resolution continuous wave optical UV-spectroscopy on the $\mathrm{A}\,^2Σ^+ \leftarrow \mathrm{X}\,^2Π_{3/2}$ transition in nitric oxide [PDF]
We report on Doppler-free continuous-wave optical UV-spectroscopy resolving the hyperfine structure of the $\mathrm{A}\,^2\Sigma^+ \leftarrow \mathrm{X}\,^2\Pi_{3/2}$ transition in nitric oxide for total angular momenta $J_X=1.5-19.5$ on the $\mathrm{oP_{12ee}}$ branch.
arxiv +1 more source
Nitric oxide and TNFα are critical regulators of reversible lymph node vascular remodeling and adaptive immune response. [PDF]
Lymph node (LN) vascular growth, at the level of the main arteriole, was recently characterized for the first time during infection. Arteriole diameter was shown to increase for at least seven days and to occur via a CD4(+) T cell dependent mechanism ...
Stephanie L Sellers+2 more
doaj +1 more source
Emergent dynamics in an astrocyte-neuronal network coupled via nitric oxide [PDF]
In the brain, both neurons and glial cells work in conjunction with each other during information processing. Stimulation of neurons can cause calcium oscillations in astrocytes which in turn can affect neuronal calcium dynamics. The "glissandi" effect is one such phenomenon, associated with a decrease in infraslow fluctuations, in which synchronized ...
arxiv +1 more source
Autophagy contributes to angiotensin II induced dysfunction of HUVECs
Background: Signal transduction of Angiotensin II (Ang II) induced autophagy and its role in Ang II–induced dysfunction of HUVECs are still unclear. Methods: HUVECs are stimulated with different doses of Ang II (10-9-10-5 mol/L) for different time (6–48 ...
Di Liu+7 more
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A mathematical model for breath gas analysis of volatile organic compounds with special emphasis on acetone [PDF]
Recommended standardized procedures for determining exhaled lower respiratory nitric oxide and nasal nitric oxide have been developed by task forces of the European Respiratory Society and the American Thoracic Society. These recommendations have paved the way for the measurement of nitric oxide to become a diagnostic tool for specific clinical ...
arxiv +1 more source
Dietary capsaicin-mediated attenuation of hypertension in a rat model of renovascular hypertension
Background: Capsaicin, a pungent component of chili pepper, has been reported to decrease blood pressure (BP) and to cause vasorelaxation via nitric oxide (NO) production.
Yukiko Segawa+7 more
doaj +1 more source
Obesity is always associated with chronic (low-grade) inflammation, which causes insulin-resistance in type-II diabetes mellitus. Dramatically, cholesterol level rises with starting diabetes and lower insulin level.
Ladan Ahmad-Khosravi-Choghakhor+1 more
doaj +1 more source
Triggering or enhancing antitumor activity of tumor-associated macrophages is an attractive strategy for cancer treatment. We have previously shown that the cytokine interferon-γ (IFN-γ), a type II IFN, could synergize with toll-like receptor (TLR ...
Elisabeth Müller+7 more
doaj +1 more source