Results 11 to 20 of about 69,950 (233)

Characterization of a constitutive type III nitric oxide synthase in human U937 monocytic cells: stimulation by soluble CD23

open access: greenImmunology, 1997
The soluble cleavage fragment of the low‐affinity immunoglobulin E (IgE) receptor/CD23 (sCD23 25 000 MW) and antibodies directed against their receptors on monocytes, CD11b and CD11c, stimulate the production of nitric oxide (NO) by these cells and we have suggested that the enzyme involved could be related to the endothelial constitutive type III ...
V. Roman   +6 more
openaire   +4 more sources

Activation of Type III Nitric Oxide Synthase in Astrocytes Following a Neurotropic Viral Infection

open access: hybridVirology, 1996
Type III nitric oxide synthase (type III NOS), also known as endothelial cell nitric oxide synthase (eNOS or ecNOS or NOS-3), is a constitutively expressed, calcium- and calmodulin-dependent, isoform of NOS. Its expression has been localized to endothelial cells and a subset of neurons in the brain.
Carol Shoshkes Reiss   +3 more
openaire   +4 more sources

L-NA-Sensitive rCBF Augmentation during Vibrissal Stimulation in Type III Nitric Oxide Synthase Mutant Mice [PDF]

open access: bronzeJournal of Cerebral Blood Flow & Metabolism, 1996
Regional cerebral blood flow (rCBF) was studied in type III nitric oxide (NO) synthase (endothelial, eNOS) mutant and wild type mice during mechanical whisker stimulation before and after nitro-L-arginine (L-NA) superfusion using the closed cranial window technique.
Jianya Ma   +4 more
openaire   +4 more sources

[3H]L-NG-Nitroarginine Binding after Transient Focal Ischemia and NMDA-Induced Excitotoxicity in Type I and Type III Nitric Oxide Synthase Null Mice [PDF]

open access: bronzeJournal of Cerebral Blood Flow & Metabolism, 1997
We investigated the density and distribution of nitric oxide synthase (NOS) binding by quantitative autoradiography using [3H]L- NG-nitroarginine ([3H]L-NNA) after transient focal ischemia or intrastriatal injection of N-methyl-D-aspartate (NMDA) in wild-type (SV-129 and C57black/6) and type I (neuronal) and type III (endothelial) NOS-deficient mice ...
Paul L. Huang   +6 more
openaire   +5 more sources

The 25-kDa soluble CD23 activates type III constitutive nitric oxide-synthase activity via CD11b and CD11c expressed by human monocytes. [PDF]

open access: bronzeThe Journal of Immunology, 1997
Abstract CD23, a low-affinity receptor for IgE, was recently shown to bind to CD11b and CD11c molecules on human monocytes. The 25-kDa soluble fragment of CD23 (sCD23), was tested for its capacity to elicit various signaling pathways in human monocytes.
J P, Aubry   +9 more
openaire   +3 more sources

Differential response of basal and tetrahydrobiopterin-stimulated activities of placental type III nitric oxide synthase to sodium dodecyl sulphate: relation to dimeric structure [PDF]

open access: closedMolecular Human Reproduction, 1998
The major enzyme isoform that synthesizes nitric oxide (NO) in first trimester human placentae is endothelial or type III NO-synthase (NOS III) which exhibits high specific activity in the microsomal fraction. In the present study, we investigated the possible protective and enzyme-stabilizing role of tetrahydropterin (BH4).
Miklós Sahin-Tóth   +2 more
openaire   +4 more sources

Correction: Antitumoral gene-based strategy involving nitric oxide synthase type III overexpression in hepatocellular carcinoma [PDF]

open access: bronzeGene Therapy, 2023
Á J. De la Rosa   +12 more
openaire   +2 more sources

Inhibition of nitric oxide production of activated mice peritoneal macrophages is independent of the Toxoplasma gondii strain [PDF]

open access: yesMemorias do Instituto Oswaldo Cruz, 2021
BACKGROUND Toxoplasma gondii causes toxoplasmosis and is controlled by activated macrophages. However, infection of macrophages by tachyzoites induces TGF-β signaling (TGF-s) inhibiting nitric oxide (NO) production.
João Cláudio Damasceno-Sá   +9 more
doaj   +1 more source

Association of endothelial nitric oxide synthase gene (G894T) polymorphism and hypertension in diabetic Bataknese patients [PDF]

open access: yesMedicinski Glasnik, 2020
Aim To assess endothelial nitric oxide synthase (eNOS) gene (G894T) polymorphism and nitric oxide (NO) level in hypertensive diabetic Bataknese patients.
Jelita Siregar   +4 more
doaj   +1 more source

Association between the Polymorphisms rs2070744, 4b/a and rs1799983 of the NOS3 Gene with Chronic Kidney Disease of Uncertain or Non-Traditional Etiology in Mexican Patients

open access: yesMedicina, 2023
Background and Objectives: Chronic Kidney Disease of uncertain or non-traditional etiology (CKDnT) is a form of chronic kidney disease of undetermined etiology (CKDu) and is not associated with traditional risk factors.
Alejandro Marín-Medina   +3 more
doaj   +1 more source

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