Results 11 to 20 of about 129,732 (281)

The 25-kDa soluble CD23 activates type III constitutive nitric oxide-synthase activity via CD11b and CD11c expressed by human monocytes. [PDF]

The Journal of Immunology, 1997
Abstract CD23, a low-affinity receptor for IgE, was recently shown to bind to CD11b and CD11c molecules on human monocytes. The 25-kDa soluble fragment of CD23 (sCD23), was tested for its capacity to elicit various signaling pathways in human monocytes.
J P, Aubry, N, Dugas, S, Lecoanet-Henchoz, F, Ouaaz, H, Zhao, J F, Delfraissy, P, Graber, J P, Kolb, B, Dugas, J Y, Bonnefoy   +9 more
openaire   +3 more sources

[³H]L-N^G-Nitroarginine Binding after Transient Focal Ischemia and NMDA-Induced Excitotoxicity in Type I and Type III Nitric Oxide Synthase Null Mice [PDF]

Journal of Cerebral Blood Flow & Metabolism, 1997
We investigated the density and distribution of nitric oxide synthase (NOS) binding by quantitative autoradiography using [3H]L- NG-nitroarginine ([3H]L-NNA) after transient focal ischemia or intrastriatal injection of N-methyl-D-aspartate (NMDA) in wild-type (SV-129 and C57black/6) and type I (neuronal) and type III (endothelial) NOS-deficient mice ...
H, Hara, C, Ayata, P L, Huang, C, Waeber, G, Ayata, M, Fujii, M A, Moskowitz   +6 more
openaire   +4 more sources

L-NA-Sensitive rCBF Augmentation during Vibrissal Stimulation in Type III Nitric Oxide Synthase Mutant Mice [PDF]

Journal of Cerebral Blood Flow & Metabolism, 1996
Regional cerebral blood flow (rCBF) was studied in type III nitric oxide (NO) synthase (endothelial, eNOS) mutant and wild type mice during mechanical whisker stimulation before and after nitro-L-arginine (L-NA) superfusion using the closed cranial window technique.
C, Ayata, J, Ma, W, Meng, P, Huang, M A, Moskowitz   +4 more
openaire   +3 more sources

Differential response of basal and tetrahydrobiopterin-stimulated activities of placental type III nitric oxide synthase to sodium dodecyl sulphate: relation to dimeric structure [PDF]

Molecular Human Reproduction, 1998
The major enzyme isoform that synthesizes nitric oxide (NO) in first trimester human placentae is endothelial or type III NO-synthase (NOS III) which exhibits high specific activity in the microsomal fraction. In the present study, we investigated the possible protective and enzyme-stabilizing role of tetrahydropterin (BH4).
M, Tóth, Z, Kukor, M, Sahin-Tóth
openaire   +3 more sources

Antitumoral gene-based strategy involving nitric oxide synthase type III overexpression in hepatocellular carcinoma

Gene Therapy, 2015
Hepatocellular carcinoma develops in cirrhotic liver. The nitric oxide (NO) synthase type III (NOS-3) overexpression induces cell death in hepatoblastoma cells. The study developed gene therapy designed to specifically overexpress NOS-3 in cultured hepatoma cells, and in tumors derived from orthotopically implanted tumor cells in fibrotic livers. Liver
De la Rosa, Angel J., Rodríguez Hernández, María Angeles, González Ojeda, Raúl, Romero Brufau, Santiago, Navarro-Villarán, Elena, Barrera Pulido, Lidia, Pereira, Sheila, Marín, Luis M., López Bernal, F., Álamo, José M., Gómez Bravo, Miguel A., Padillo, Francisco J., Muntané Relat, Jordi   +12 more
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Characterization of a constitutive type III nitric oxide synthase in human U937 monocytic cells: stimulation by soluble CD23

Immunology, 1997
The soluble cleavage fragment of the low‐affinity immunoglobulin E (IgE) receptor/CD23 (sCD23 25 000 MW) and antibodies directed against their receptors on monocytes, CD11b and CD11c, stimulate the production of nitric oxide (NO) by these cells and we have suggested that the enzyme involved could be related to the endothelial constitutive type III ...
V, Roman, N, Dugas, A, Abadie, C, Amirand, H, Zhao, B, Dugas, J P, Kolb   +6 more
openaire   +4 more sources

Nonpregnant Sheep Uterine Type I and Type III Nitric Oxide Synthase Expression Is Differentially Regulated by Estrogen1 [PDF]

Biology of Reproduction, 1999
Jie Zhang, G. Angela Massmann, Charles P. Mirabile, Jorge P. Figueroa   +3 more
openaire   +2 more sources

Correction: Antitumoral gene-based strategy involving nitric oxide synthase type III overexpression in hepatocellular carcinoma [PDF]

Gene Therapy, 2023
Á J. De la Rosa, Á Rodríguez-Hernández, R. González, S. Romero-Brufau, E. Navarro-Villarán, L. Barrera-Pulido, S. Pereira, L. M. Marín, F. López-Bernal, J. M. Álamo, M. A. Gómez-Bravo, F. J. Padillo, J. Muntané   +12 more
openaire   +2 more sources

[17-beta estradiol induces type III nitric oxide synthase expression in cultured endothelial cells].

Archivos de cardiologia de Mexico, 2002
It has been suggested that the low incidence of cardiovascular diseases in premenopausal women, compared with that in men of the same age, is related to the interaction between the nitric oxide (NO) pathway and estrogens. The aim of the present work was to characterize the mechanism by which 17-beta estradiol produces an increment in NO release in ...
G M, Jiménez, I, Ceja Ochoa, A, Hernández Pérez, B, Escalante Acosta   +3 more
openaire   +2 more sources

Inhibition of nitric oxide production of activated mice peritoneal macrophages is independent of the Toxoplasma gondii strain [PDF]

Memorias do Instituto Oswaldo Cruz, 2021
BACKGROUND Toxoplasma gondii causes toxoplasmosis and is controlled by activated macrophages. However, infection of macrophages by tachyzoites induces TGF-β signaling (TGF-s) inhibiting nitric oxide (NO) production.
João Cláudio Damasceno-Sá, Fernanda Silva de Souza, Thiago Alves Teixeira dos Santos, Fábio Conceição de Oliveira, Maria de Fátima Sarro da Silva, Raul Ramos Furtado Dias, Wanderley de Souza, Andrea Cristina Veto Arnholdt, Sergio Henrique Seabra, Renato Augusto DaMatta   +9 more
doaj   +1 more source