Results 21 to 30 of about 129,732 (281)

Association of endothelial nitric oxide synthase gene (G894T) polymorphism and hypertension in diabetic Bataknese patients [PDF]

Medicinski Glasnik, 2020
Aim To assess endothelial nitric oxide synthase (eNOS) gene (G894T) polymorphism and nitric oxide (NO) level in hypertensive diabetic Bataknese patients.
Jelita Siregar, Ratna Akbari Ganie, Dharma Lindarto, Erna Mutiara, Delfitri Munir   +4 more
doaj   +1 more source

Association between the Polymorphisms rs2070744, 4b/a and rs1799983 of the NOS3 Gene with Chronic Kidney Disease of Uncertain or Non-Traditional Etiology in Mexican Patients

Medicina, 2023
Background and Objectives: Chronic Kidney Disease of uncertain or non-traditional etiology (CKDnT) is a form of chronic kidney disease of undetermined etiology (CKDu) and is not associated with traditional risk factors.
Alejandro Marín-Medina, José Juan Gómez-Ramos, Norberto Mendoza-Morales, Luis Eduardo Figuera-Villanueva   +3 more
doaj   +1 more source

Sirtuin 3 deficiency promotes acute kidney injury induced by sepsis via mitochondrial dysfunction and apoptosis [PDF]

Iranian Journal of Basic Medical Sciences, 2021
Objective(s): To explore the regulation mechanism of Sirtuin 3 (SIRT3) on the mitochondrial function and apoptosis of acute kidney injury (AKI) in septic mice.Materials and Methods: The sepsis-induced AKI model was constructed in the wild-type and SIRT3 ...
Heng Fan, Jian-wei Le, Min Sun, Jian-hua Zhu   +3 more
doaj   +1 more source

The Antitumoral Effect of Paris Saponin II on Head and Neck Squamous Cell Carcinomas Mediated via the Nitric Oxide Metabolic Pathway

Frontiers in Cell and Developmental Biology, 2022
Paris saponin has shown great therapeutic value in cancer therapy. We used isolated Paris saponin II (PSII), an active component of Paris saponin, and demonstrated its antitumor effect on human head and neck squamous cell carcinoma cell lines ...
Wenwen Qi, Wenwen Qi, Fangyuan Zhu, Min Wang, Zhenxiao Teng, Zhenxiao Teng, Runtong Xu, Yue Xi, Qiu Meng, Xinhao Wu, Xinhao Wu, Hui Zhao, Min Ma, Xiaozhi Hou, Baowei Wang, Xiaoming Li, Chengcheng Liu, Xiang Zhang, Fenglei Xu, Ming Xia, Ming Xia   +20 more
doaj   +1 more source

Adventitial Collagen Cross-Linking by Glutaraldehyde Reinforcing Human Saphenous Vein - Implication for Coronary Artery Bypass Grafting [PDF]

Brazilian Journal of Cardiovascular Surgery, 2022
Introduction: A weak venous wall is one of the major reasons contributing to vein graft failure after coronary artery bypass grafting (CABG). We investigated whether adventitial collagen cross-linking by glutaraldehyde reinforces venous wall, preserving ...
Changcheng Liu, Duanduan Chen, Zhenfeng Li, Huanming Xu, Chengxiong Gu   +4 more
doaj   +1 more source

Effects of Ovine Monocyte-Derived Macrophage Infection by Recently Isolated Toxoplasma gondii Strains Showing Different Phenotypic Traits

Animals, 2022
Ovine toxoplasmosis is one the most relevant reproductive diseases in sheep. The genetic variability among different Toxoplasma gondii isolates is known to be related to different degrees of virulence in mice and humans, but little is known regarding its
Raquel Vallejo, Julio Benavides, Noive Arteche-Villasol, Mercedes Fernández-Escobar, María Del Carmen Ferreras, Valentín Pérez, Daniel Gutiérrez-Expósito   +6 more
doaj   +1 more source

Effect of miR-134 against myocardial hypoxia/reoxygenation injury by directly targeting NOS3 and regulating PI3K/Akt pathway [PDF]

Acta Cirúrgica Brasileira, 2019
Purpose To reveal the function of miR-134 in myocardial ischemia. Methods Real-time PCR and western blotting were performed to measure the expression of miR-134, nitric oxide synthase 3 (NOS3) and apoptotic-associated proteins. Lactic dehydrogenase (LDH)
Jian-Min Xiao, Ji-Jia Wang, Li-Li Sun
doaj   +1 more source

The Major Heat Shock Proteins, Hsp70 and Hsp90, in 2-Methoxyestradiol-Mediated Osteosarcoma Cell Death Model [PDF]

, 2020
2-Methoxyestradiol is one of the natural 17β-estradiol derivatives and a potential novel anticancer agent currently being under evaluation in advanced phases of clinical trials.
Cappello F., Daca A., Gorska-Ponikowska M., Kuban-Jankowska A., Luu H. H., Marino Gammazza A., Wierzbicka J. M., Wozniak M., Zmijewski M. A.   +8 more
core   +1 more source

Cellular responses of Candida albicans to phagocytosis and the extracellular activities of neutrophils are critical to counteract carbohydrate starvation, oxidative and nitrosative stress [PDF]

, 2012
Acknowledgments We thank Alexander Johnson (yhb1D/D), Karl Kuchler (sodD/D mutants), Janet Quinn (hog1D/D, hog1/cap1D/D, trx1D/D) and Peter Staib (ssu1D/D) for providing mutant strains.
A Cederlund, A da Silva Dantas, Alistair J. P. Brown, B Amulic, B Enjalbert, B Enjalbert, B Hube, B Hube, BD Ullmann, Bernhard Hube, BH Youseff, BS Hromatka, C Fradin, Christine Dunker, CJ Barelle, CJ Barelle, CJ Heilmann, D Wilson, DA Smith, DL Moyes, DL Moyes, DM Arana, DR Wysong, FC Fang, GM Chaves, Hanna Windecker, I Rubin-Bejerano, I Wozniok, ID Jacobsen, IE Frohner, Iryna M. Bohovych, J Cheetham, M de Jesus-Berrios, M Martchenko, MA Wheeler, MC Lorenz, MC Lorenz, MG Netea, Oliver Kurzai, Oscar Zaragoza, P Nordenfelt, Pedro Miramón, R Alonso-Monge, R Pathania, RA Calderone, RI Lehrer, SC Cheng, TM Stevanin, TM Stevanin, V Brinkmann, W Bellamy, W Chiranand   +51 more
core   +9 more sources

Implementation of pro- and anti-inflammatory mechanisms of sirtuin-1 in patients with chronic obstructive pulmonary disease and chronic coronary syndrome and their combination

Zaporožskij Medicinskij Žurnal, 2023
One of the key pathogenetic aspects of chronic obstructive pulmonary disease (COPD) and chronic coronary syndrome (CCS) is endothelial dysfunction.
Ya. V. Chobanu, T. O. Ilashchuk
doaj   +1 more source