Results 21 to 30 of about 120,160 (335)

Synthesis of Highly Substituted Oxazoles through Iodine(III)-Mediated Reactions of Ketones with Nitriles

Molecules, 2012
In the presence of trifluoromethanesulfonic acid (TfOH) or bis(trifluoromethane-sulfonyl)imide (Tf2NH), iodosobenzene (PhI=O) efficiently promoted the reactions of dicarbonyl compounds as well as monocarbonyl compounds with nitriles to give 2,4 ...
Yuji Hanzawa, Akio Saito, Nao Hyodo
doaj   +1 more source

Crystal structure, Hirshfeld surface analysis and interaction energy and DFT studies of 3-{(2Z)-2-[(2,4-dichlorophenyl)methylidene]-3-oxo-3,4-dihydro-2H-1,4-benzothiazin-4-yl}propanenitrile

Acta Crystallographica Section E: Crystallographic Communications, 2019
The title compound, C18H12Cl2N2OS, consists of a dihydrobenzothiazine unit linked by a –CH group to a 2,4-dichlorophenyl substituent, and to a propanenitrile unit is folded along the S...N axis and adopts a flattened-boat conformation. The propanenitrile
Nada Kheira Sebbar, Brahim Hni, Tuncer Hökelek, Abdelhakim Jaouhar, Mohamed Labd Taha, Joel T. Mague, El Mokhtar Essassi   +6 more
doaj   +1 more source

Synthesis of Simplified Azasordarin Analogs as Potential Antifungal Agents [PDF]

, 2019
A new series of simplified azasordarin analogs was synthesized using as key steps a Diels–Alder reaction to generate a highly substituted bicyclo[2.2.1]heptane core, followed by a subsequent nitrile alkylation.
Dockendorff, Chris, Wu, Yibiao
core   +4 more sources

Isothiocyanates, Nitriles, and Epithionitriles from Glucosinolates Are Affected by Genotype and Developmental Stage in Brassica oleracea Varieties

Frontiers in Plant Science, 2017
Vegetables of the Brassica oleracea group, such as broccoli, cauliflower, and cabbage, play an important role for glucosinolate consumption in the human diet.
Franziska S. Hanschen, Monika Schreiner
doaj   +1 more source

Covalent Reversible Inhibitors of Cysteine Proteases Containing the Nitrile Warhead: Recent Advancement in the Field of Viral and Parasitic Diseases

Molecules, 2022
In the field of drug discovery, the nitrile group is well represented among drugs and biologically active compounds. It can form both non-covalent and covalent interactions with diverse biological targets, and it is amenable as an electrophilic warhead ...
Simone Brogi, Roberta Ibba, Sara Rossi, Stefania Butini, Vincenzo Calderone, Sandra Gemma, Giuseppe Campiani   +6 more
doaj   +1 more source

Direct Regioselective C-H Cyanation of Purines

Molecules, 2023
A direct regioselective C-H cyanation of purines was developed through a sequential triflic anhydride activation, nucleophilic cyanation with TMSCN, followed by a process of base-mediated elimination of triflous acid (CF3SO2H).
Luyong Li, Jie Hu, Yuqing Fu, Xiaolin Shi, Hongguang Du, Jiaxi Xu, Ning Chen   +6 more
doaj   +1 more source

Novel ETFE based radiation grafted poly(styrene sulfonic acid-co-methacrylonitrile) proton conducting membranes with increased stability [PDF]

, 2009
Styrene radiation grafted ETFE based proton conducting membranes are subject to degradation under fuel cell operating conditions and show a poor stability. Lifetimes exceeding 250 h can only be achieved with crosslinked membranes.
Alkan Gursel, Selmiye, Alkan Gürsel, Selmiye, Ben youcef, Hicham, Gubler, Lorenz, Henkensmeier, Dirk, Scherer, Gunther G., Scherer, Günther G., Wokaun, Alexander   +7 more
core   +2 more sources

4-(4-Acetyl-5-methyl-1H-1,2,3-triazol-1-yl)benzonitrile: crystal structure and Hirshfeld surface analysis

Acta Crystallographica Section E: Crystallographic Communications, 2018
The title compound, C12H10N4O, comprises a central 1,2,3-triazole ring (r.m.s. deviation = 0.0030 Å) flanked by N-bound 4-cyanophenyl and C-bound acetyl groups, which make dihedral angles of 54.64 (5) and 6.8 (3)° with the five-membered ring, indicating ...
Julio Zukerman-Schpector, Cássio da S. Dias, Ricardo S. Schwab, Mukesh M. Jotani, Edward R. T. Tiekink   +4 more
doaj   +1 more source

Hyperpolarization of Nitrile Compounds Using Signal Amplification by Reversible Exchange

Molecules, 2020
Signal Amplification by Reversible Exchange (SABRE), a hyperpolarization technique, has been harnessed as a powerful tool to achieve useful hyperpolarized materials by polarization transfer from parahydrogen.
Sarah Kim, Sein Min, Heelim Chae, Hye Jin Jeong, Sung Keon Namgoong, Sangwon Oh, Keunhong Jeong   +6 more
doaj   +1 more source

Reactivity of the biphasic trichloroacetonitrile-CH2Cl2/H2O2 system in the epoxidation of soybean oil

Grasas y Aceites, 2002
In this work we report on the epoxidation of soybean oil by the trichloroacetonitrile -CH2Cl2/H2O2 byphasic system. The reaction was carried out at room temperature and, most importantly, in non acid conditions which prevent the opening of the oxirane ...
Annelise E. Gerbase, Márcia C. Brasil, José R. Gregório, Ana N.F. Mendes, Maria Luiza A. von Holleben, Márcia Martinelli   +5 more
doaj   +1 more source