Results 21 to 30 of about 159,122 (346)

2,6-Dibromo-4-nitrobenzonitrile

IUCrData, 2017
Molecules of the title compound, C7H2Br2N2O2, have C2v symmetry and each lie on a twofold axis that bisects the benzene ring and its nitro and cyano substituents.
Wayland E. Noland, Kenneth J. Tritch
doaj   +1 more source

Crystal structures of methyl 3,5-dibromo-4-cyanobenzoate and methyl 3,5-dibromo-4-isocyanobenzoate

Acta Crystallographica Section E: Crystallographic Communications, 2018
The title crystals, C9H5Br2NO2, are the first reported 2,6-dihalophenyl cyanide–isocyanide pair that have neither three- nor two-dimensional isomorphism. Both crystals contain contacts between the carbonyl O atom and a Br atom.
Wayland E. Noland, Ryan J. Herzig, Abigail J. Engwall, Renee C. Jensen, Kenneth J. Tritch   +4 more
doaj   +1 more source

Synthesis of Simplified Azasordarin Analogs as Potential Antifungal Agents [PDF]

, 2019
A new series of simplified azasordarin analogs was synthesized using as key steps a Diels–Alder reaction to generate a highly substituted bicyclo[2.2.1]heptane core, followed by a subsequent nitrile alkylation.
Dockendorff, Chris, Wu, Yibiao
core   +4 more sources

Diacylfuroxans Are Masked Nitrile Oxides That Inhibit GPX4 Covalently.

Journal of the American Chemical Society, 2019
GPX4 represents a promising yet difficult-to-drug therapeutic target for the treatment of, among others, drug-resistant cancers. Although most GPX4 inhibitors rely on a chloroacetamide moiety to modify covalently the protein's catalytic selenocysteine ...
J. Eaton, Richard A. Ruberto, A. Kramm, V. Viswanathan, S. Schreiber   +4 more
semanticscholar   +1 more source

Synthesis, characterization and study of antibacterial activity of some novel tetrazole derivatives

Orbital: The Electronic Journal of Chemistry, 2011
This work aims at synthesizing novel tetrazole derivatives from phenothiazine. Phenothiazine is first converted into corresponding nitrile by reacting it with aldehyde, sodium metabisulphite and sodium cyanide.
Subramaniyan Arulmurugan, Helen P. Kavitha, Bathey R. Venkatraman   +2 more
doaj   +1 more source

Synthesis of Highly Substituted Oxazoles through Iodine(III)-Mediated Reactions of Ketones with Nitriles

Molecules, 2012
In the presence of trifluoromethanesulfonic acid (TfOH) or bis(trifluoromethane-sulfonyl)imide (Tf2NH), iodosobenzene (PhI=O) efficiently promoted the reactions of dicarbonyl compounds as well as monocarbonyl compounds with nitriles to give 2,4 ...
Yuji Hanzawa, Akio Saito, Nao Hyodo
doaj   +1 more source

Nitrile-assistant eutectic electrolytes for cryogenic operation of lithium ion batteries at fast charges and discharges [PDF]

, 2014
The charge/discharge characteristics of lithium ion batteries at low temperature (LT = -20 ??C) are enhanced by using ethylene carbonate (EC)-based electrolytes with the help of assistant solvents of nitriles. Conventional liquid electrolytes (e.g.
Abu-Lebdeh, Abu-Lebdeh, Bak, Brunet, Ding, Ding, Ding, Dong-Gil Sung, Duncan, Gering, Hyun-Kon Song, Kamaya, Kim, Kim, Lee, Myung-Su Seo, Ruiz, Sazhin, Shiao, Smart, Smart, Smart, Smart, Smart, Smart, Wang, Yoon-Gyo Cho, Young-Soo Kim, Zhang   +28 more
core   +1 more source

Crystal structure, Hirshfeld surface analysis and interaction energy and DFT studies of 3-{(2Z)-2-[(2,4-dichlorophenyl)methylidene]-3-oxo-3,4-dihydro-2H-1,4-benzothiazin-4-yl}propanenitrile

Acta Crystallographica Section E: Crystallographic Communications, 2019
The title compound, C18H12Cl2N2OS, consists of a dihydrobenzothiazine unit linked by a –CH group to a 2,4-dichlorophenyl substituent, and to a propanenitrile unit is folded along the S...N axis and adopts a flattened-boat conformation. The propanenitrile
Nada Kheira Sebbar, Brahim Hni, Tuncer Hökelek, Abdelhakim Jaouhar, Mohamed Labd Taha, Joel T. Mague, El Mokhtar Essassi   +6 more
doaj   +1 more source

The Active Site Sulfenic Acid Ligand in Nitrile Hydratases Can Function as a Nucleophile [PDF]

, 2014
Nitrile hydratase (NHase) catalyzes the hydration of nitriles to their corresponding commercially valuable amides at ambient temperatures and physiological pH.
Holz, Richard C., Liu, Dali, Martinez, Salette, Sanishvili, Ruslan, Wu, Rui   +4 more
core   +3 more sources

Isothiocyanates, Nitriles, and Epithionitriles from Glucosinolates Are Affected by Genotype and Developmental Stage in Brassica oleracea Varieties

Frontiers in Plant Science, 2017
Vegetables of the Brassica oleracea group, such as broccoli, cauliflower, and cabbage, play an important role for glucosinolate consumption in the human diet.
Franziska S. Hanschen, Monika Schreiner
doaj   +1 more source