Results 151 to 160 of about 2,971,196 (335)

Mitochondria‐Localized Nestin Protects Mesenchymal Stem Cells from Senescence by Maintaining Cristae Structure and Function

Advanced Science, EarlyView.
Nestin localizes to the mitochondrial IMS through its MTS and the TOM20 import machinery. Within the mitochondria, Nestin interacts with Mic60 via its C‐terminal Tail3 domain. Loss of mitochondrial Nestin disrupts cristae architecture, leading to mitochondrial swelling, bioenergetic dysfunction, and ultimately the senescence of hMSCs.
Hainan Chen, Jinsi Chen, Li Huang, Xingqiang Lai, Kai Xia, Qiying Lu, Bingbing Xie, Yinong Huang, Yuan Qiu, Tao Wang, Jianqi Feng, Yuanjun Guan, Siyao Che, Jiancheng Wang, Andy Peng Xiang   +14 more
wiley   +1 more source

Syntheses of Isoxazoline-Based Amino Acids by Cycloaddition of Nitrile Oxides and Their Conversion into Highly Functionalized Bioactive Amino Acid Derivatives [PDF]

, 2012
F. Fülöp, Lóránd Kiss, Melinda Nonn
openalex   +1 more source

Next‐Generation Piezoelectric Materials in Wearable and Implantable Devices for Continuous Physiological Monitoring

Advanced Science, EarlyView.
An analysis of literature trends and a historical overview of organic and inorganic piezoelectric materials, focusing on their structural diversity, functional mechanisms, and inherent characteristics. It then explores cutting‐edge developments in material synthesis, fabrication processes, and performance optimization, highlighting their applicability ...
Bangul Khan, Umay Amara, Bilawal Khan, Wasim Ullah Khan, Rafi u Shan Ahmad, Muhammad Shehzad Khan, Mohamed Elhousseini Hilal, Bee Luan Khoo   +7 more
wiley   +1 more source

POSTN‐Mediated Interplay of M1 Polarized Macrophage with Tendon‐Derived Stem Cells to Drive Traumatic Heterotopic Ossification Formation through PTK7/ATK Signaling?

Advanced Science, EarlyView.
The mechanism diagram reveals that the formation of trauma‐induced heterotopic ossification (HO) is accompanied by the polarization of macrophages toward the M1 phenotype. Additionally, the extracellular vesicles secreted by M1 macrophages, which contain periostin (POSTN), directly bind to PTK7 in tendon‐derived stem cells (TDSCs).
Hang Liu, Xinyue Li, Mengyi Li, Ziyang Sun, Xu Wang, Juehong Li, Binbin Xu, Qian Chen, Cunyi Fan, Hongjiang Ruan   +9 more
wiley   +1 more source

Novel Stereoselective Synthesis of (E)-α,β-Unsaturated Nitriles and Ketones by the Tandem reaction of Deprotonation–oxidation–Wittig Reaction from Phosphonium Salts

, 2003
Zhi‐Zhen Huang, Ruo‐Jun Sun
openalex   +1 more source

Single Mitochondrion Morphology‐Function Relationship Analysis Using Fluorescent Probes and Artificial Intelligence

Advanced Science, EarlyView.
An integrated strategy combining a mitochondria‐targeted fluorescent probe set and an AI framework enables simultaneous analysis of mitochondrial morphology and function at the single organelle level. By fusing multi‐parametric features, machine learning classification accurately distinguishes individual mitochondria under hypoxia‐related conditions ...
Yang Ding, Bin Fang, Qingzhe Li, Biying Zhang, Jintao Li, Hua Bai, Nicolas H. Voelcker, Bo Peng, Xuekang Yang, Lin Li   +9 more
wiley   +1 more source

Diels-Alder versus 1,3-dipolar cycloaddition pathways in the reaction of C20 fullerene and 2-furan nitrile oxide

, 2015
Seyyed Amir Siadati, A. Mirabi
semanticscholar   +1 more source

Nitrile butadiene rubber composites reinforced with reduced graphene oxide and carbon nanotubes show superior mechanical, electrical and icephobic properties

Composites Science And Technology, 2018
L. Valentini, S. Bittolo Bon, M. Hernández, M. López-Manchado, Nicola Maria Pugno   +4 more
semanticscholar   +1 more source

Intramolecular 1,3-dipolar cycloaddition reaction of novel 2-azetidinone-tethered alkenyl nitrile oxides

, 2004
Benito Alcaide, Pedro Almendros, Elena Sáez   +2 more
openalex   +2 more sources

Synthesis of Functional Materials Using N‐heterocyclic Amines Beyond Melamine

Advanced Science, EarlyView.
Melamine has long enabled supramolecular assemblies, polymers, and carbon nitrides, yet related N‐heterocyclic amines remain underexplored. This review highlights advances with melamine analogues such as 6‐phenyl‐, 6‐methyl‐triazine diamines and 2,4,6‐triaminopyrimidine, focusing on how structural variation governs reactivity, condensation, and ...
Jesús Barrio, Arne Thomas
wiley   +1 more source