Results 41 to 50 of about 3,048,164 (380)
Controllable cyanation of carbon-hydrogen bonds by zeolite crystals over manganese oxide catalyst
Nature Communications, 2017 Sustainable strategies for nitrile synthesis are needed. Here, the authors report an environmentally benign, selective heterogeneous catalyst for the synthesis of nitriles by the oxidative cyanation of carbon and hydrogen (C-H) bonds, which comprises ...
Liang Wang +5 more
doaj +1 more source
Organic LettersElectron-rich, electron-deficient, and non-activated alkenes can be rapidly functionalized by in situ-generated difluoromethyl nitrile oxide. The (3+2) cycloaddition proceeds at room temperature, has broad functional group tolerance, and can be used for ...
B. Chalyk +3 more
semanticscholar +1 more source
Side-chain Modifications of Highly Functionalized 3(2H)-Furanones
Molecules, 2012 A series of 3(2H)-furanones, based on side-chain modifications of a parent 3(2H)-furanone, was synthesized in good yield. The parent compound was prepared by hydrogenolysis, and subsequent acid hydrolysis, of isoxazole derivatives.
Gil Valdo José da Silva +3 more
doaj +1 more source
eXPRESS Polymer Letters, 2009 The aim of this work was to study the activity of several nanosized zinc oxides in the crosslinking of carboxylated nitrile elastomer (XNBR). In this article, we discuss the effect of zinc oxide nanoparticles with respect to their specific surface area ...
doaj +1 more source
Synthesis of a Novel Tetracyclic Isoxazole by Intramolecular Nitrile Oxide Cycloaddition
MolbankIntramolecular cycloadditions have the great advantage of forming two rings simultaneously. We report the use of intramolecular [3 + 2] cycloaddition of the nitrile oxide derived from an N-propargylbenzimidazole oxime in the synthesis of a hitherto ...
Gavin R. Hoffman, Allen M. Schoffstall
doaj +1 more source
Beilstein Journal of Organic Chemistry, 2016 Reactions of β-azolyl enamines and nitrile oxides were studied by both experimental and theoretical methods. (E)-β-(4-Nitroimidazol-5-yl), (5-nitroimidazol-4-yl) and isoxazol-5-yl enamines smoothly react regioselectively at room temperature in dioxane ...
Ilya V. Efimov +10 more
doaj +1 more source
Improving Thermo-Oxidative Stability of Nitrile Rubber Composites by Functional Graphene Oxide
Materials, 2018 Graphene oxide (GO), modified with anti-aging agent p-phenylenediamine (PPD), was added into nitrile rubber (NBR) in order to improve the thermo-oxidative stability of NBR.
R. Zhong +5 more
semanticscholar +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
The preparation of ketene dithioacetals and thiophenes from chloropyridines containing an active methylene group [PDF]
, 2010 The base catalysed reaction of carbon disulphide with the active methylene groups of chloropyridines 4 and 7, followed by alkylation with reagents which also contain active methylene groups, lead to ketene dithioacetals.
Bremner, David H. +2 more
core +3 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source