Results 141 to 150 of about 239,878 (262)

Dyotropic Rearrangement of Hypervalent Iodine Species: Migrative Heterofunctionalization of Quaternary Carbons

Angewandte Chemie, EarlyView.
1,2‐Aryl migration involving in situ‐generated alkyl iodine(III) species proceeds through a previously unrecognized 1,2‐C/I(III) dyotropic rearrangement. Migratory aryl fluorination, acetoxylation, and alkoxylation of 2‐alkyl‐2‐aryl‐3‐iodopropanoates provide α‐heterofunctionalized products, accompanied by aryl migration from the α‐ to the β‐position ...
Chen‐Xu Liu, Qian Wang, Matthew D. Wodrich, Jieping Zhu   +3 more
wiley   +2 more sources

Preparation and reactivity of some stable nitrile oxides and nitrones

ARKIVOC, 2000
Paul W. Groundwater, Miklós Nyerges, Imre Fejes, David E. Hibbs, David Bendell, Rosaleen J. Anderson, Alexander McKillop, Toqir Sharif, Weimin Zhang   +8 more
doaj   +1 more source

1,4‐Brook Rearrangement of β‐Silyl Allylic Alcohols: Trisubstituted Alkenes by Copper‐Mediated Stereoretentive ipso‐Substitution Reactions

Angewandte Chemie, EarlyView.
To fully leverage the power of the ruthenium‐catalyzed trans‐hydrosilylation of propargyl alcohols, it was necessary to develop a practical and robust method for the activation of those products that carry the silyl group distal to the hydroxy substituent.
Paul Haf‐Moths, Jack L. Sutro, Alois Fürstner   +2 more
wiley   +2 more sources

Intramolecular 1,3-dipolar cycloaddition reaction of novel 2-azetidinone-tethered alkenyl nitrile oxides

ARKIVOC, 2004
Benito Alcaide, Pedro Almendros, Elena Sáez   +2 more
doaj   +1 more source

A Modular Synthesis of C5‐Sulfenyl Thiazoles via an Intermolecular Pummerer Rearrangement: An Underexplored Scaffold for Medicinal Chemistry

Angewandte Chemie, EarlyView.
Modular access to underexplored C5‐sulfenyl thiazoles via an intermolecular Pummerer rearrangement is reported. The methodology exhibits a broad functional group tolerance enabling the seamless design of trisubstituted thiazole cores bearing a sulfur handle for further elaboration.
Joe L. Smy, Theo C. Webb, Barnaby W. Greenland, S. Mark Roe, John Spencer, Storm Hassell‐Hart   +5 more
wiley   +2 more sources

Synthesis of spiroisoxazolines through cycloadditions of nitrile oxides with 3-methylenequinuclidine

ARKIVOC, 2005
Connie K. Y. Lee, Christopher J. Easton, G. Paul Savage, Gregory W. Simpson   +3 more
doaj   +1 more source

Glutathione‐Responsive Acyl‐Modifications for Targeted RNA Decaging and Prolonged Protein Synthesis

Angewandte Chemie, EarlyView.
The self‐immolation of disulfide‐based mRNA modifications in response to endogenous glutathione (GSH) promotes a gradual release of translatable mRNA within the cell, leading to improved nuclease resistance, tunable release properties, and a significant increase (up to 600%) of target protein production over time. This strategy offers an exciting proof
Mary E. Flood, Sathishkumar Kurusamy, Mark Berney, C. Mark Smales, Elizabeth M. Topp, Joanna F. McGouran, Steven Ferguson   +6 more
wiley   +2 more sources

Correction: Novel valdecoxib derivatives by ruthenium(ii)-promoted 1,3-dipolar cycloaddition of nitrile oxides with alkynes - synthesis and COX-2 inhibition activity. [PDF]

Medchemcomm, 2018
Roscales S, Bechmann N, Weiss DH, Köckerling M, Pietzsch J, Kniess T.   +5 more
europepmc   +1 more source

Covalent Organic Framework Colloids With Core‐Shell Donor/Acceptor Architecture and Ultralong‐Lived Charge‐Separated States

Angewandte Chemie, EarlyView.
Uniform core‐shell colloidal particles of Covalent Organic Frameworks (COFs) are synthesized by a seeded growth of electron‐acceptor COF shells on electron‐donor COF cores. The resulting p‐n heterojunction enables efficient separation of photogenerated charges, which persist for minutes. These core‐shell COFs show efficient CO2 photoreduction to CO and
Ting Yu, Cory Ruchlin, Tong Li, Mohammad Hossein Gohari, Zhechang He, Zeina Chamseddine, Chang Wan Kang, Dongling Ma, Dmytro F. Perepichka   +8 more
wiley   +2 more sources

1,3-Dipolar Cycloaddition of Nitrile Imines and Nitrile Oxides to Exocyclic C=N Bonds-An Approach to <i>Spiro</i>-N-Heterocycles. [PDF]

Int J Mol Sci
Petrova JV, Kukushkin ME, Beloglazkina EK.   +2 more
europepmc   +1 more source