Results 11 to 20 of about 4,461 (274)

One Step Regioselective Synthesis of 5-Aminoisoxazoles from Nitrile Oxides and α-Cyanoenamines

Molecules, 2004
The 1,3-dipolar cycloaddition of nitrile oxides to 1-cyanoenamines gives 5-aminoisoxazoles regioselectively. Moderate to good yields could be obtained depending on the method used to generate the nitrile oxides. The intermediate isoxazolines could not be
Aïcha Derdour, Michel Vaultier, Amar Saad   +2 more
doaj   +2 more sources

Novel valdecoxib derivatives by ruthenium(ii)-promoted 1,3-dipolar cycloaddition of nitrile oxides with alkynes - synthesis and COX-2 inhibition activity. [PDF]

Medchemcomm, 2018
By Ru(ii)-promoted 1,3-dipolar cycloaddition of nitrile oxides with alkynes 3,4-diaryl-substituted isoxazoles are formed in one step, showing high inhibition potency for COX-2.
Roscales S, Bechmann N, Weiss DH, Köckerling M, Pietzsch J, Kniess T.   +5 more
europepmc   +2 more sources

MnVI-NP–Catalyzed Generation of Nitrile Oxides: Easy Access to Isoxazolines and Isoxazoles via Stereoselective 1,3-Dipolar Cyclo­addition Reactions

SynOpen, 2022
The versatility and effectiveness of MnVI-NPs as a catalyst is examined for the generation of nitrile oxides from aldoximes and subsequent 1,3-dipolar cycloaddition reactions.
Yasmin Saima, Saikat Khamarui
doaj   +1 more source

Ultrasound-assisted one-pot three-component synthesis of new isoxazolines bearing sulfonamides and their evaluation against hematological malignancies

Ultrasonics Sonochemistry, 2021
In the present study, following a one-pot two-step protocol, we have synthesized novel sulfonamides-isoxazolines hybrids (3a-r) via a highly regioselective 1,3-dipolar cycloaddition. The present methodology capitalized on trichloroisocyanuric acid (TCCA)
Aicha Talha, Cécile Favreau, Maxence Bourgoin, Guillaume Robert, Patrick Auberger, Lahcen EL Ammari, Mohamed Saadi, Rachid Benhida, Anthony R. Martin, Khalid Bougrin   +9 more
doaj   +1 more source

Studies on the [2+3] cycloaddition reaction of nitrile oxides to abietic acid esters [PDF]

Journal of the Serbian Chemical Society, 2019
[2+3] Dipolar cycloadditions of aromatic nitrile oxides to abietic acid esters were investigated. The reactions showed complete site selectivity and regioselectivity, while the stereoselectivity depended on the structures of the dipolarophiles.
Gucma Mirosław, Gołębiewski Marek W., Żelechowski Krzysztof, Krawczyk Maria   +3 more
doaj   +1 more source

Mechanochemical Dimerization of Aldoximes to Furoxans

Molecules, 2022
Solvent-free mechanical milling is a new, environmentally friendly and cost-effective technology that is now widely used in the field of organic synthesis.
Run-Kai Fang, Kuan Chen, Chuang Niu, Guan-Wu Wang   +3 more
doaj   +1 more source

A Weinreb Nitrile Oxide and Nitrone for Cycloaddition. [PDF]

ChemInform, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Ajit K, Parhi, Richard W, Franck
openaire   +2 more sources

Reactions of 5-Aroylmethylene-3-benzyl-4-oxo-2-thioxo-1,3-thiazolidines with Nitrile Oxides

Molecules, 2001
E,Z-5-Aroylmethylene-3-benzyl-4-oxo-2-thioxo-1,3-thiazolidines (3a-c) react with 4-methoxy and 4-chlorophenylnitrile oxides (4a and b) in pyridine solution to afford one or more of the following compounds: Z-3, Z-2,4-dioxo analogues 5 and 3,6-diaryl-1,4 ...
Ahmed S. A. Youssef, Kamal A. Kandeel
doaj   +1 more source

Synthesis, DFT Study and Antibacterial Activity of some Isoxazoline Derivatives Containing 1,4-benzothiazin-3-one Nucleus Obtained Using 1,3-dipolar Cycloaddition Reaction [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2020
Novel series of isoxazoline derivatives containing 1,4-benzothiazin-3-one ring (6a-h) were synthesized via 1,3-dipolar cycloaddition reactions of arylnitrile oxides 5a-d on 4-allyl-2-(substituted)-1,4-benzothiazin-3-ones 3 and 4 led to polyheterocyclic ...
Sebbar Nada Kheira, Taha Mohamed Labd, Ellouz Mohamed, Essassi El Mokhtar, Zerzouf Abdelfettah, Karrouchi Khalid, Ouzidan Younes, Mennane Zakaria, T. Mague Joel   +8 more
doaj   +1 more source

The Participation of 3,3,3-Trichloro-1-nitroprop-1-ene in the [3 + 2] Cycloaddition Reaction with Selected Nitrile N-Oxides in the Light of the Experimental and MEDT Quantum Chemical Study

Molecules, 2021
The regioselective zw-type [3 + 2] cycloaddition (32CA) reactions of a series of aryl-substituted nitrile N-oxides (NOs) with trichloronitropropene (TNP) have been both experimentally and theoretically studied within the Molecular Electron Density Theory
Karolina Zawadzińska, Mar Ríos-Gutiérrez, Karolina Kula, Przemysław Woliński, Barbara Mirosław, Tomasz Krawczyk, Radomir Jasiński   +6 more
doaj   +1 more source