Results 21 to 30 of about 24,787 (265)

Rotational spectroscopic study and astronomical search for propiolamide in Sgr B2(N) [PDF]

A&A 647, A55 (2021), 2021
For all the amides detected in the interstellar medium (ISM), the corresponding nitriles or isonitriles have also been detected in the ISM, some of which have relatively high abundances. Among the abundant nitriles for which the corresponding amide has not yet been detected is cyanoacetylene (HCCCN), whose amide counterpart is propiolamide (HCCC(O)NH ...
arxiv   +1 more source

Stereospecific synthesis of syn-alpha-oximinoamides by a three-component reaction of isocyanides, syn-chlorooximes, and carboxylic acids [PDF]

, 2011
A stereospecific multicomponent reaction among isocyanides, nitrile N-oxides and carboxylic acids provides an efficient synthesis of biologically relevant syn \u3b1 ...
Galli, Simona, Mossetti, Riccardo, Pirali, Tracey, Tron, Gian Cesare   +3 more
core   +1 more source

Ultrasound-assisted one-pot three-component synthesis of new isoxazolines bearing sulfonamides and their evaluation against hematological malignancies

Ultrasonics Sonochemistry, 2021
In the present study, following a one-pot two-step protocol, we have synthesized novel sulfonamides-isoxazolines hybrids (3a-r) via a highly regioselective 1,3-dipolar cycloaddition. The present methodology capitalized on trichloroisocyanuric acid (TCCA)
Aicha Talha, Cécile Favreau, Maxence Bourgoin, Guillaume Robert, Patrick Auberger, Lahcen EL Ammari, Mohamed Saadi, Rachid Benhida, Anthony R. Martin, Khalid Bougrin   +9 more
doaj  

Synthesis, DFT Study and Antibacterial Activity of some Isoxazoline Derivatives Containing 1,4-benzothiazin-3-one Nucleus Obtained Using 1,3-dipolar Cycloaddition Reaction [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2020
Novel series of isoxazoline derivatives containing 1,4-benzothiazin-3-one ring (6a-h) were synthesized via 1,3-dipolar cycloaddition reactions of arylnitrile oxides 5a-d on 4-allyl-2-(substituted)-1,4-benzothiazin-3-ones 3 and 4 led to polyheterocyclic ...
Sebbar Nada Kheira, Taha Mohamed Labd, Ellouz Mohamed, Essassi El Mokhtar, Zerzouf Abdelfettah, Karrouchi Khalid, Ouzidan Younes, Mennane Zakaria, T. Mague Joel   +8 more
doaj   +1 more source

The Participation of 3,3,3-Trichloro-1-nitroprop-1-ene in the [3 + 2] Cycloaddition Reaction with Selected Nitrile N-Oxides in the Light of the Experimental and MEDT Quantum Chemical Study

Molecules, 2021
The regioselective zw-type [3 + 2] cycloaddition (32CA) reactions of a series of aryl-substituted nitrile N-oxides (NOs) with trichloronitropropene (TNP) have been both experimentally and theoretically studied within the Molecular Electron Density Theory
Karolina Zawadzińska, Mar Ríos-Gutiérrez, Karolina Kula, Przemysław Woliński, Barbara Mirosław, Tomasz Krawczyk, Radomir Jasiński   +6 more
doaj   +1 more source

Inverse electron-demand 1,3-dipolar cycloaddition of nitrile oxide with common nitriles leading to 3-functionalized 1,2,4-oxadiazoles [PDF]

, 2011
A carbamoyl-substituted nitrile oxide was generated upon treatment of easily available 2-methyl-4-nitro-3-isoxazolin-5(2H)-one with THF (not dried); the reaction proceeded efficiently even in the absence of any special reagents and reaction conditions ...
1020, 1021, 1022, 1023, 1024, 1025, 1026, 1027, Ariga, Masahiro, Hirao, Shotaro, Ise, Yumiko, Kobiro, Kazuya, Nishiwaki, Nagatoshi, Okajima, Yoshikazu, Saigo, Kazuhiko, Sawayama, Jun   +15 more
core   +1 more source

Direct oxidation of Δ2-isoxazolines synthesis by metal ion-mediated diastereoface-selective 1,3-dipolar cycloaddition with “activated” DMSO

Arabian Journal of Chemistry, 2017
A series of 4-hydroxyl-Δ2-isoxazol-6(6aH)-one derivatives was prepared by magnesium ion-mediated diastereoface-selective 1,3-dipolar cycloaddition of aromatic nitrile oxides with pyrrolidinone derivatives.
Naoufel Ben Hamadi, Moncef Msaddek
doaj   +1 more source

[3 + 2] Cycloaddition reactions of nitrile oxides generated in situ from aldoximes with alkenes and alkynes under ball-milling conditions

Green Chemistry Letters and Reviews, 2022
A convenient and efficient [3 + 2] cycloaddition reaction of alkenes and alkynes with the in situ generated nitrile oxides from aldoximes in the presence of NaCl, Oxone and Na2CO3 has been developed to afford a series of isoxazoles and isoxazolines at ...
Run-Kai Fang, Zheng-Chun Yin, Jun-Shen Chen, Guan-Wu Wang   +3 more
doaj   +1 more source

Functionalisation of Artemisinin and Its Ring-contracted Derivatives

Molecules, 2007
Isoxazoline analogues of artemisinin were obtained in low yield and low diastereoselectivity from the 1,3-dipolar cycloaddition of nitrile oxides. Alternatively, starting from the aldehyde 7, a number of transformations - Wittig reaction and reduction ...
Wim Dehaen, Sarah Van Mierloo, Tine Van Neck   +2 more
doaj   +1 more source

Origin of Life Molecules in the Atmosphere After Big Impacts on the Early Earth [PDF]

arXiv, 2023
The origin of life on Earth would benefit from a prebiotic atmosphere that produced nitriles, like HCN, which enable ribonucleotide synthesis. However, geochemical evidence suggests that Hadean air was relatively oxidizing with negligible photochemical production of prebiotic molecules.
arxiv