Red blood cell endothelial nitric oxide synthase: A major player in regulating cardiovascular health
British Journal of Pharmacology, EarlyView., 2023 Abstract Red blood cells (RBCs) have traditionally been seen as simple carriers of gases and nutrients in the body. One important non‐canonical function of RBCs in the cardiovascular system is the regulation of nitric oxide (NO) metabolism. It has been shown that RBCs can scavenge NO, transport NO metabolites and produce NO in hypoxic conditions ...
Anthea LoBue +7 more
wiley +1 more source
A haloarchaeal ferredoxin electron donor that plays an essential role in nitrate assimilation [PDF]
, 2011 In the absence of ammonium, many organisms, including the halophilic archaeon Haloferax volcanii DS2 (DM3757), may assimilate inorganic nitrogen from nitrate or nitrite, using a ferredoxin-dependent assimilatory NO3-/NO2- reductase pathway.
Bonete, Maria José +5 more
core +1 more source
Should the non‐canonical pathway of nitric oxide generation be targeted in hypertensive pregnancies?
British Journal of Pharmacology, EarlyView., 2023 Abstract Hypertension in pregnancy is prevalent, affecting around 10% of pregnancies worldwide, and significantly increases the risk of adverse outcomes for both mothers and their babies. Current treatment strategies for pregnant women with hypertension are limited, and new approaches for the management of hypertension in pregnancy are urgently needed.
Elizabeth C. Cottrell
wiley +1 more source
Nature Communications, 2020 Siroheme is an essential bacterial iron tetrapyrrole used by siroheme-dependent sulfite and nitrite reductases. Here the authors shed light on the catalytic mechanisms of siroheme synthase through the structures of the bifunctional dehydrogenase ...
Joseph M. Pennington +4 more
doaj +1 more source
Highly diverse nirK genes comprise two major clades that harbour ammonium-producing denitrifiers [PDF]
, 2016 Background: Copper dependent nitrite reductase, NirK, catalyses the key step in denitrification, i.e. nitrite reduction to nitric oxide. Distinct structural NirK classes and phylogenetic clades of NirK-type denitrifiers have previously been observed ...
Decleyre, Helen +3 more
core +3 more sources
Bacterial nitrate assimilation: gene distribution and regulation [PDF]
, 2011 In the context of the global nitrogen cycle, the importance of inorganic nitrate for the nutrition and growth of marine and freshwater autotrophic phytoplankton has long been recognized.
Andrew J. Gates +44 more
core +1 more source
Biotransformation of explosives by the old yellow enzyme family of flavoproteins [PDF]
, 2004 Several independent studies of bacterial degradation of nitrate ester explosives have demonstrated the involvement of flavin-dependent oxidoreductases related to the old yellow enzyme (OYE) of yeast. Some of these enzymes also transform the nitroaromatic
Bruce, N.C. +3 more
core +2 more sources
Genetic and environmental controls on nitrous oxide accumulation in lakes. [PDF]
PLoS ONE, 2015 We studied potential links between environmental factors, nitrous oxide (N2O) accumulation, and genetic indicators of nitrite and N2O reducing bacteria in 12 boreal lakes.
Jatta Saarenheimo +5 more
doaj +1 more source
La production de nitrites lors de la dénitrification des eaux usées par biofiltration - Stratégie de contrôle et de réduction des concentrations résiduelles [PDF]
Revue des Sciences de l'Eau, 31(1), 2018, 61-73, 2017 The recent popularity of post-denitrification processes in the greater Paris area wastewater treatment plants has caused a resurgence of the presence of nitrite in the Seine river. Controlling the production of nitrite during the post-denitrification has thus become a major technical issue.
arxiv +1 more source
Resolving the contributions of the membrane-bound and periplasmic nitrate reductase systems to nitric oxide and nitrous oxide production in Salmonella enterica serovar Typhimurium [PDF]
, 2011 The production of cytotoxic nitric oxide (NO) and conversion into the neuropharmacological agent and potent greenhouse gas nitrous oxide (N2O) is linked with anoxic nitrate catabolism by Salmonella enterica serovar Typhimurium.
Anderson +50 more
core +1 more source