Results 31 to 40 of about 1,770 (208)
FEBS Letters, Volume 600, Issue 2, Page 251-266, January 2026.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
Spectral and Thermal Studies of Light Lanthanide Complexes with 4-Methoxy-3-nitrobenzoic Acid [PDF]
, 1999 4-Methoxy-3-nitrobenzoates of light lanthanides with a metal to ligand ratio of 1:3 have been obtained as hydrated salts. They have colours typical of Ln3+ ions (Pr-green, Nd-pink, Sm-cream, and La, Ce, Eu and Gd-white).
Beata Bocian +2 more
core +1 more source
ChemistrySelect, Volume 11, Issue 1, 8 January 2026.ABSTRACT This study investigates the biological properties of methanolic and petroleum ether (PE) extracts from the roots and flowers of Thapsia garganica L., providing new insights into its potential medicinal uses. Although T. garganica has a long history in traditional medicine, the anticholinesterase and tyrosinase‐inhibiting activities of this ...
Rania Arabi +11 more
wiley +1 more source
Studies Of Some 3, 4-Dichlorophenacyl Esters Derivatives: Synthesis, Characterization, Crystal Structure Determination And Antioxidant Properties [PDF]
, 2021 In this research, a series of nineteen 3, 4-dichlorophenacyl esters 2(a−s) were synthesized and crystallized by using slow evaporation method. The crystal structures were characterized by FT-IR and NMR spectroscopic analyses and further determined by ...
Sim, Ai Jia
core
Dietary nitrate supplementation mitigates age‐related changes at the neuromuscular junction in mice
The Journal of Physiology, Volume 604, Issue 2, Page 886-916, 15 January 2026.Abstract figure legend Ageing is associated with a decline in muscle mass and strength, namely sarcopenia, significantly impacting the quality of life in older individuals. Different strategies are being explored to counteract these detrimental effects. In the present study, we investigated a non‐invasive nutritional approach: the impact of 2 months of
Maira Rossi +9 more
wiley +1 more source
Journal of Basic Microbiology, Volume 65, Issue 12, December 2025.ABSTRACT Polyhydroxybutyrate (PHB) is a natural polyester synthesized and stored intracellularly as cytoplasmic granules, serving as a carbon and energy reserve in certain bacteria. These granules are surrounded by a variety of proteins, including those directly involved in PHB metabolism—both in its synthesis and degradation—as well as a group of non ...
Jessica Ruiz‐Escobedo +8 more
wiley +1 more source
Copper‐Catalyzed Hydrosilylation of Nitroarenes: Chemoselective Reduction to Aromatic Amines
ChemCatChem, Volume 17, Issue 22, November 24, 2025.A commercially available copper‐hydride complex was utilized as an effective catalyst for the hydrosilylation of nitroarenes to aromatic amines. Nitroarenes with diverse functionalities were efficiently reduced to anilines with good chemoselectivity. The practicality of this reduction protocol was demonstrated through the synthesis of pharmaceuticals ...
Pritirekha Mallick +4 more
wiley +1 more source
Preparation and spectra of m-nitrobenzoates and m-aminobenzoates [PDF]
, 1953 A study of the synthesis of a series of new m-nitrobenzoates, m-aminobenzoates and several derivatives of the latter is presented. Physisal constants and analytical determinations are presented, including the ultraviolet absorption spectra of the ...
Kapsamalis, Peter Tikey
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Synthesis and Anticancer Potential of New Benzimidazole Theranostic
ChemistryOpen, Volume 14, Issue 11, November 2025.Recent advances have highlighted benzimidazole's importance in anticancer drug discovery. A novel series of benzimidazole analogs is designed and synthesized, with V7 showing broad anticancer activity and selectivity, possibly linked to SIRT2 inhibition.
Sahani Sandalima Uthumange +2 more
wiley +1 more source
Identification of a New Interesting BAG3 Modulator Able to Disrupt Cancer‐Related Pathways
ChemMedChem, Volume 20, Issue 20, October 15, 2025.Compound 2, identified through in‐house screening and derived from SP18, exhibits high affinity for BAG3, as demonstrated by Surface Plasmon Resonance and docking studies. It induces a dose‐dependent proapoptotic response in HeLa cells, evidenced by increased Annexin V/PI staining, underscoring the triazole scaffold as a promising platform for BAG3 ...
Dafne Ruggiero +10 more
wiley +1 more source