Results 41 to 50 of about 573 (176)

Solvolysis of exo- and endo-Tricyclo[3,3,0,02,8]oct-3-yl p-Nitrobenzoates

, 1974
exo- and endo-Tricyclo[3,3,0,02.8]octan-3-ols (7a) and (8a) have been prepared and their structure elucidated. Solvolysis of the derived p-nitrobenzoate of the endo alcohol in 70% aqueous acetone at 100 occurred some ten times faster than the p ...
RG Buckeridge, BL Johnson, KJ Frayne
core   +1 more source

Allylic Cations in Solvolysis. A Case of Non-Participation [PDF]

, 1984
The rate constants and secondary deuterium Isotope ef'fects are measured in the solvo'lysis of various allyHc p-nitrobenzoates. The obtained results are explained by differences in inductive effects o>f vardous groups in the side-chain. These results
Ladika, Mladen, Sunko, Dionis E.
core   +1 more source

In Vitro Antioxidant, Antibacterial, and Cholinesterase‐Inhibitory Properties of an Aqueous Euphorbia macroclada Root Extract Obtained by Ultrasound‐Assisted Extraction

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
The aqueous root extract of Euphorbia macroclada was obtained using ultrasound‐assisted extraction (UAE). The extract showed remarkable butyrylcholinesterase (BChE) inhibition relevant to Alzheimer's disease. Strong antioxidant capacity was demonstrated through multiple radical scavenging and reducing assays.
Abdulkadir Gül, Fırat Yılmaz, Fevzi Topal, İnanç Özgen, Ercan Aydoğmuş, Hasan Arslanoğlu   +5 more
wiley   +1 more source

α‐Glucosidase and Acetylcholinesterase (AChE) Inhibitory Activities, Larvicidal Potential and GC–MS Analysis of Endlicheria paniculata: A Combined Experimental and Molecular Docking Study

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
This study investigates the essential oil composition of E. paniculata wood, bark, and leaves by GC–MS. Biological evaluations of the leaf essential oil reveal promising larvicidal potential against Aedes aegypti and in vitro inhibitory activities against α‐glucosidase and acetylcholinesterase (AChE), supported by molecular docking simulations ...
Jenifer Priscila de Araujo, Luiz Everson Da Silva, Wanderlei do Amaral, Michele Debiasi Alberton, Ana Helena Loos Moritz, Fernando Cesar Martins Betim, Deise Prehs Montrucchio, Marilis Dallarmi Miguel, Josiane de Fátima Gaspari Dias, Hélcio Silva Dos Santos, Emmanuel Silva Marinho, Márcia Machado Marinho, Jacilene Silva, Obdulio Gomes Miguel   +13 more
wiley   +1 more source

Thermal Stability of the Guinea Green B Solution With Substrate and Its Application for the Detection of Cholinesterase Inhibitors

Analysis &Sensing, Volume 6, Issue 5, September 2026.
A Guinea Green B/butyrylthiocholine iodide solution offers a simple visual colorimetric approach for detecting cholinesterase inhibitors (neostigmine, VX, and A‐234). The aqueous formulation remains practically functional after 150 days at 60 °C, whereas the phosphate‐buffered variant rapidly degrades.
Lukáš Matějovský, Vladimír Pitschmann   +1 more
wiley   +1 more source

Structural Investigations into the β-Effect of Pentavalent Silicon

, 2016
Ester and ether derivatives of 2-[(8-dimethylaminonaphthalen-1-yl)dimethylsilanyl]ethanol (10a) were prepared as part of a preliminary study to determine the β-effect of pentavalent silicon.
Jonathan M. White (1366602), Marisa Spiniello (2450545)   +1 more
core   +3 more sources

Fragment‐Based Screening of Heterocyclic Electrophiles Identified Acrylamide Bioisoteres for Covalent KRasG12C Inhibitors

Archiv der Pharmazie, Volume 359, Issue 9, September 2026.
We screened acrylamide bioisosteres against KRasG12C and prioritized primary hits by their GSH reactivity, labeling efficiency and specificity. The most promising fragment was combined with a KRas‐binding scaffold. Covalent binding, inhibitory activity and selectivity were confirmed via MS, NMR, biochemical and cell viability assays.
Nikolett Péczka, Aaron Keeley, Péter Ábrányi‐Balogh, Zoltán Orgován, László Petri, Emma K. Grant, Chad Quinn, Soma Csanády, Ivan Randelovic, József Tóvári, Jacob Bush, György M. Keserű   +11 more
wiley   +1 more source

Bioactive Phenolics of Lygeum spartum L.: Insights Into Antioxidant, Anticholinesterase, and Antityrosinase Activities

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Phenolic profile and bioactivity of Lygeum spartum L. ABSTRACT The phenolic composition of roots and leaves of Lygeum spartum L., a Mediterranean Poaceae species, was analyzed by HPLC–DAD, revealing an organ‐specific distribution of phenolic compounds, with ferulic acid identified as the predominant phenolic compound in the methanolic leaf extract (4 ...
Zohra Arabi, Rania Arabi, Dilaycan Çam, Cansel Çakir, Mehmet Öztürk, Hamdi Bendif, Gharieb S. El‐Sayyad, Mohamed A. M. Ali, Walid Elfalleh, Stefania Garzoli   +9 more
wiley   +1 more source

Synthesis, Characterization, and Multifunctional Bioactivity of ZnO/CuO@Amoxicillin Nanocomposites: A Synergistic Nano‐Platform With Potent Antioxidant, Anti‐Inflammatory, Antidiabetic, and Anti‐Cholinesterase Activities

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
ZnO/CuO@amoxicillin nanocomposite, synthesized via sol–gel route, demonstrates exceptional multifunctional performance. It strongly inhibits α‐amylase and α‐glucosidase, effectively suppresses inflammation, and exhibits superior antioxidant activity surpassing ascorbic acid.
Hocine Sadam Nesrat, Abdelatif Aouadi, Ibtissam Laib, Salah Eddine Laouini, Abderrhmane Bouafia, Djamila Hamada Saoud, Halima Zidane, Hafidha Terea, Mahmood M. S. Abdullah, Tomasz Trzepieciński, Dalila Saidane‐Mosbahi   +10 more
wiley   +1 more source

First Report on the Phytochemical and Pharmacological Properties of Hedysarum yilmazunalii

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Hedysarum yilmazunalii was collected from Erzincan, Türkiye. The leaf, stem, and root parts were then used for methanolic extraction. The extracts were analyzed for their phytochemical composition by LC–MS/MS and tested for antioxidant, enzyme inhibitory, and antiproliferative activities.
Etem Osma, Tuğçe Varol, Samed Şimşek, Sevgi Altın, Mustafa Abdullah Yılmaz, Ali Aydın, Müjgan Elveren, Ali Kandemir   +7 more
wiley   +1 more source