Results 21 to 30 of about 412 (137)

Mean weighted residuals reveal systematic overestimation of Bragg intensities in single‐crystal diffraction

Journal of Applied Crystallography, Volume 59, Issue 3, Page 707-715, June 2026.
Analysis of more than 8000 published data sets demonstrates that systematic overestimation of observed intensities can deceptively improve common agreement factors and atomic displacement parameters, masking underlying deficiencies in data quality.The mean value of weighted residuals (⟨ζ⟩) was analysed for 8424 published single‐crystal X‐ray data sets ...
Julian Henn, Piero Macchi, Toms Rekis
wiley   +1 more source

Tetrameric hotdog‐fold structure and catalytic mechanism of the SaPaaI thioesterase from Staphylococcus aureus

Protein Science, Volume 35, Issue 5, May 2026.
Abstract Acyl‐CoA thioesterases hydrolyse thioester bonds to release free fatty acyl chains and coenzyme A (CoA), thereby regulating lipid metabolism, signaling, and membrane homeostasis. Here, we present the structural and functional characterization of the Paal‐like thioesterase SAV0944 (SaPaaI) from Staphylococcus aureus.
Yogesh Khandokar, Parul Srivastava, Renate H. M. Schwab, Ashish Sethi, Naveen Vankadari, Jade K. Forwood   +5 more
wiley   +1 more source

The Arsenal of Aromatic Degrading Bacteria: How They Sense, Chase, Adapt and Destroy Environmental Pollutants

Microbial Biotechnology, Volume 19, Issue 5, May 2026.
In the environment, bacteria sense aromatic pollutants, migrate toward them, adapt to toxicity, and deploy specialized uptake and catabolic systems. Genomic plasticity, metabolic versatility and division of labor within populations together aid in the degradation of persistent aromatics, highlights that biodegradation is driven by various eco ...
Prashant S. Phale, Tushar Dhamale, Satyajit Subhash   +2 more
wiley   +1 more source

Bed rest decreases resting skeletal muscle O2 uptake and resting energy expenditure in young and elderly subjects

Experimental Physiology, Volume 111, Issue 5, Page 2599-2612, 1 May 2026.
Abstract A decrease in resting muscle O2 uptake (V̇O2m${\dot V_{{{\mathrm{O}}_2}{\mathrm{m}}}}$) described during bed rest (BR) could determine a decreased whole‐body resting energy expenditure (REE), potentially useful during prolonged spaceflights. Two groups of recreationally active men (young [Y], n = 8, age 23 ± 5 years; elderly [E], n = 10, age ...
Giovanni Baldassarre, Simone Porcelli, Lucrezia Zuccarelli, Lorenza Brocca, Noemi Arboit, Laura Gobbo, Michele Lacerenza, Alessio Marciano, Chiara Motto, Giulia Sanguin, Mladen Gasparini, Boštjan Šimunič, Rado Pišot, Marco Narici, Bruno Grassi   +14 more
wiley   +1 more source

Synthesis of p‐Coumarates With Potential Anti‐Alzheimer's Action: Enzyme Inhibition and In Silico Studies

Chemistry &Biodiversity, Volume 23, Issue 4, April 2026.
ABSTRACT Alzheimer's disease (AD) is a fatal neurodegenerative disorder that affects cognition, memory, and behavior. Such a disease is considered the most common cause of dementia and affects a large portion of the elderly population worldwide. Currently, cholinesterase inhibitors are used to reduce the symptoms and rate of progression of this disease.
Susiany Pereira Lopes, Jeremias Justo Emídio, Allana Brunna Sucupira Duarte, Ilkay Erdogan Orhan, Fatma Sezer Senol Deniz, Ramin Ekhteiari Salmas, Damião Pergentino de Sousa   +6 more
wiley   +1 more source

Research advances in the applications of mitochondria‐targeted cyanine dyes in imaging

VIEW, Volume 7, Issue 2, April 2026.
Near‐infrared (NIR) fluorescence imaging, a novel non‐invasive diagnostic tool, plays a crucial role in the imaging and monitoring of solid tumors. At its core are NIR fluorescent dyes, which are widely utilized due to their ability to minimize tissue autofluorescence interference, thereby significantly enhancing the signal‐to‐noise ratio (SNR) and ...
Hongye Liao, Jingyu Deng, Qin Li, Tong Xia, Xun Yang, Simei Yang, Changzhen Sun, Xia Xiong, Li Liu   +8 more
wiley   +1 more source

Metabolic and Redox‐Related Effects of Mauritia flexuosa (Buriti) Oil Supplementation in Wistar Rats

Journal of Food Science, Volume 91, Issue 4, April 2026.
ABSTRACT Mauritia flexuosa (buriti) oil is rich in oleic and palmitic fatty acids, bioactive compounds associated with inflammation regulation, redox balance, and metabolism. This study evaluated the effects of buriti oil supplementation on body and bone composition, biochemical parameters, and redox balance in male Wistar rats.
Letícia de Almeida Sant’ Anna Trindade, Beatriz Alem Nascimento de Araújo, Gabriel de Alcantara Noblat, Karen Pereira Coutinho, Karla de Araújo Coutinho, Renata Nascimento Matoso Souto, Anderson Junger Teodoro, Aline D'Avila Pereira, Mariana Sarto Figueiredo   +8 more
wiley   +1 more source

Crystal Structure of L-Histidinium 2-Nitrobenzoate [PDF]

Journal of Amino Acids, 2012
A new nonlinear optical organic compound, namely, L-histidinium 2-nitrobenzoate (abbreviated as LH2NB (I); ([C6H10N3O2]+[C7H4NO4]−)), was synthesized. The molecular structure of LH2NB (I) was elucidated using single crystal X-ray diffraction technique.
Natarajan, Subramanian, Moovendaran, Kalimuthu, Kalyana Sundar, Jeyaperumal, Ravikumar, Krishnan   +3 more
openaire   +2 more sources

Distinct contributions of O‐acetylserine sulfhydrylases to cysteine biosynthesis in Pseudomonas aeruginosa

Protein Science, Volume 35, Issue 3, March 2026.
Abstract Cysteine biosynthesis in bacteria proceeds primarily via the de novo pathway, involving serine acetyltransferase (CysE) and O‐acetylserine sulfhydrylase (OASS). This pathway is absent in humans, and its inhibition impairs microbial fitness, virulence, and antibiotic resistance, making its enzymes attractive antimicrobial targets. Most bacteria
Noemi Massa, Flavia Catalano, Silvia Fruncillo, Francesca Troilo, Marta Mellini, Filippo Favretto, Livia Leoni, Giordano Rampioni, Alessandro Giuffrè, Adele di Matteo, Alessandra Astegno   +10 more
wiley   +1 more source

Recent Advances in Vesicular Systems for Applications in Artificial Photosynthesis and Photocatalysis

Small Structures, Volume 7, Issue 2, February 2026.
Bioinspired vesicles are emerging as programmable nanoreactors for photocatalytic applications. This review covers the recent advances in artificial vesicles, including liposomes, polymersomes, proteinosomes, and hybrid vesicles, for compartmentalized photocatalysis, comparing their properties and assembly routes, showing how their properties affect ...
Edelman José Espinoza‐Suárez, Akhmet Bekaliyev, Leonardo Quesada‐Román, Laura Velasco‐Garcia, Carla Casadevall   +4 more
wiley   +1 more source