Nitrobenzoates and Nitrothiobenzoates with Activity against M. tuberculosis [PDF]
Microorganisms, 2023 Esters of weak acids have shown improved antimycobacterial activity over the corresponding free acids and nitro benzoates in particular have previously shown to have a very intriguing activity. To expand the potential of nitro-derivatives of benzoic acid
João P. Pais +6 more
doaj +5 more sources
Magnetic, spectrochemical and thermal properties of the 2-chloro-5-nitrobenzoates of Co(II), Ni(II) and Cu(II) [PDF]
Journal of the Serbian Chemical Society, 2006 Some physico-chemical properties of the 2-chloro-5-nitrobenzoates of Co(II), Ni(II) and Cu(II) were studied. The complexes were obtained as hydrates with a metal ion to ligand ratio of 1:2. All the complexes were polycrystalline compounds.
AGNIESZKA WALKÓW-DZIEWULSKA +2 more
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Benzoic Acid Derivatives as Prodrugs for the Treatment of Tuberculosis [PDF]
Pharmaceuticals, 2022 One interesting approach to fight tuberculosis is the use of prodrugs that often have shown improved biological activities over drugs with poor absorption or difficulty to cross membranes. Previous studies demonstrate that weak acids such as benzoic acid,
João P. Pais +9 more
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Molecular insights into the high-efficiency catabolism of chloramphenicol for soil bioaugmentation by [PDF]
Eco-Environment & HealthScreening microorganisms capable of efficiently degrading chloramphenicol (CAP) is critical for remediating CAP-contaminated soils. However, few bacterial strains capable of catabolizing CAP have been identified as suitable for soil application, and the ...
Qilin Wang +10 more
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Pd-catalyzed decarboxylative Heck vinylation of 2-nitrobenzoates in the presence of CuF2
Beilstein Journal of Organic Chemistry, 2010 A new protocol for the decarboxylative Heck vinylation of benzoic acids is disclosed. In the presence of a catalyst system generated in situ from Pd(OAc)2 (2 mol %), CuF2 (2 equiv), and benzoquinone (0.5 equiv) in NMP, a wide range of olefins were ...
Lukas J. Gooßen +2 more
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Steric Effects on Reaction Rates Correlation Analysis of Solvolysis Data for Tertiary Carbon Substrates [PDF]
CHIMIA, 1987 Rate constants for solvolysis of tertiary chlorides and p-nitrobenzoates are compared and converted to Bentley’s unified reactivity scale. For the majority of structures consistent behavior is observed. Deviations are interpreted in terms of F-strain dr,
Paul Müller, Jacky Blanc, Jiri Mareda
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Thiadiazoline- and Pyrazoline-Based Carboxamides and Carbothioamides: Synthesis and Inhibition against Nitric Oxide Synthase [PDF]
Journal of Chemistry, 2018 Two new families of pyrazoline and thiadiazoline heterocycles have been developed. Their inhibitory activities against two different isoforms of nitric oxide synthase (inducible and neuronal NOS) are reported.
Fabio Arias +6 more
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A Selectfluor-based Polonovski Rearrangement Leading to Novel Entities for Synthetic and Medicinal Applications. [PDF]
ChemistryStarting from carboxylic acids and Selectfluor‐derivatives, functionalized diazabicyclooctanes can be obtained via a novel Polonovski‐type rearrangement proceeding under mild reaction conditions. Besides their use in organic synthesis the unique structure and reactivity of the rearrangement products enables applications in medicinal chemistry ...
Kuhn J +5 more
europepmc +2 more sources
THE PREPARATION OF o-NITROBENZOIC ACID. [PDF]
Journal of the American Chemical Society, 1920 n ...
Reimer, Marie +1 more
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3-Methylpyridinium 4-nitrobenzoate–4-nitrobenzoic acid (1/1) [PDF]
IUCrData, 2016 In the title compound, C6H8N+·C7H4NO4−·C7H5NO4, the cation is protonated at its pyridine N atom and makes a dihedral angle of 74.14 (12)° with the benzene ring of the anion. The benzene ring of the neutral molecule and the pyridine ring are inclined at an angle of 79.20 (12)°.
P. Sivakumar +3 more
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