Results 21 to 30 of about 1,413,381 (322)
Synthesis, Reactivity, Functionalization, and ADMET Properties of Silicon-Containing Nitrogen Heterocycles. [PDF]
Barraza SJ, Denmark SE.
europepmc +2 more sources
Pivotal role of nitrogen heterocycles in Alzheimer's disease drug discovery.
Alzheimer's disease (AD) is a detrimental neurodegenerative disease that progressively worsens with time. Clinical options are limited and only provide symptomatic relief to AD patients.
Shikha Kumari +5 more
semanticscholar +1 more source
Nitrogen-containing heterocycles are ubiquitous in natural products and drugs. Various organic small molecules with nitrogen-containing heterocycles, such as nitrogen-containing boron compounds, cyanine, pyridine derivatives, indole derivatives ...
Yanan Li, Tao Liu, Jianan Sun
doaj +1 more source
The C-H functionalization of nitrogen-containing heterocycles has emerged as a powerful strategy for the construction of carbon-carbon (C-C) and carbon-heteroatom (C-X) bonds.
Ya-Nan Li +4 more
doaj +1 more source
A Review on Recent Advances in Nitrogen-Containing Molecules and Their Biological Applications
The analogs of nitrogen-based heterocycles occupy an exclusive position as a valuable source of therapeutic agents in medicinal chemistry. More than 75% of drugs approved by the FDA and currently available in the market are nitrogen-containing ...
Nagaraju Kerru +4 more
doaj +1 more source
Five-membered heterocycles are essential structural components in various antibacterial drugs; the physicochemical properties of a five-membered heterocycle can play a crucial role in determining the biological activity of an antibacterial drug.
Aura Rusu +3 more
doaj +1 more source
Fused 1,5-Naphthyridines: Synthetic Tools and Applications
Heterocyclic nitrogen compounds, including fused 1,5-naphthyridines, have versatile applications in the fields of synthetic organic chemistry and play an important role in the field of medicinal chemistry, as many of them have a wide range of biological ...
Carme Masdeu +6 more
doaj +1 more source
An electron-deficient triosmium cluster containing the thianthrene ligand: Synthesis, structure and reactivity of [Os₃(CO)₉(μ3-η2-C₁₂H₇S₂)(μ-H)] [PDF]
Reaction of [Os₃(CO)₁₀(CH₃CN)₂] with thianthrene at 80 °C leads to the nonacarbonyl dihydride compound [Os₃(CO)₉(μ-3,4-η²-C₁₂H₆S₂)(μ-H)₂] (1) and the 46-electron monohydride compound [Os₃(CO)₉(μ₃-η²-C₁₂H₇S₂)(μ-H)] (2).
Hassan, Mohammad R. +7 more
core +1 more source
Nitrogen heterocycles from trimethylbenzenes
AbstractThe reaction between 1,2,4‐trimethylbenzene 1, isobutyric aldehyde, and cyanoacetic ester afforded a mixture of three products: 3,3,5,6,8‐ pentamethyl‐1,2,3,4‐tetraisoquinolylidene‐1‐acetic acid ether (2) and its 3,3,5,6,7‐pentamethyl‐(3)‐ and 3,3,6,7,8‐pentamethyl‐1,2,3,4‐tetraisoquinolyli‐ dene‐1‐acetic acid ether isomers (3) in ratio 1:5:1. ©
Yu. V. Shklyaev +6 more
openaire +1 more source
Development of covalent triazine frameworks as heterogeneous catalytic supports [PDF]
Covalent triazine frameworks (CTFs) are established as an emerging class of porous organic polymers with remarkable features such as large surface area and permanent porosity, high thermal and chemical stability, and convenient functionalization that ...
Krishnaraj, Chidharth +3 more
core +1 more source

