Results 111 to 120 of about 22,395 (232)
What's new? While the effectiveness of systemic anticancer therapy is well documented, it commonly causes severe toxicity. This study of the 467 systemic anticancer therapy agents currently approved globally for clinical and/or research purposes found that peripheral neurotoxicity is associated with 45% of classical chemotherapies, 21% of targeted ...
Cassie Higgins +3 more
wiley +1 more source
Nitrogen mustard drug resistance in B-cell chronic lymphocytic leukemia
Previous studies of nitrogen mustard drug resistance in B-cell chronic lymphocytic leukemia (B-CLL) indicated that resistance was a result of enhanced DNA repair associated with increased expression of two DNA repair genes, ERCC-1 and alkyl-N-purine DNA ...
Bramson, Jonathan
core
Comparison of Cisplatin and Nitrogen Mustard Derivatives in Cancer Treatment
Platinum-containing complexes and nitrogen mustard derivatives are two drug families for cancer treatment. The two core drugs of the families were Cisplatin, created in 1845, and Chlormethine (mustine), created in 1925. Cisplatin is used to treat cancers
Liu, Ethan, Ung, Jane, Zhao, Qinliang
core
This review analyzes single/combined abiotic (light, water, nutrients, hormones) and biotic (microbes, yeast) elicitors regulating signaling, gene expression, and metabolism to boost plant secondary metabolites. It highlights synergistic multielicitor strategies for crop quality and functional foods, while critically addressing current limitations and ...
Yifei Sun +6 more
wiley +1 more source
A study of the chemistry of nitrogen mustard by N.M.R. spectroscopy [PDF]
This thesis describes the use of high-field n.m.r. spectroscopy, in part combined with stable isotope labelling, to study the solution chemistry of nitrogen mustard (2-chloro-(N-2-chloroethyl)-N-methylethanamine).
Kebbell, Michael James
core
Carbon quantum dots (CQDs) play a significant role in supporting the UN SDGs by promoting the sustainable management of energy, healthcare, remediation, and agriculture in a multidisciplinary manner. It focuses on reducing waste, toxicity, and energy use while utilizing renewable resources.
Manish Kumar Sah +6 more
wiley +1 more source
Azacrown Ethers from Mustard Carbonate Analogues
Polycondensation of a nitrogen mustard carbonate analogue with aromatic diols under dilution conditions affords a series of azacrowns previously not easily accessible as they require multistep synthesis including protection, purification, cyclization and
Udrea, I +13 more
core +1 more source
The schematic illustrates that corneal injury imparted by a stromal incision or by toxic chemical exposure causes corneal Schwann cells (cSCs) and axons to degenerate rapidly, resulting in impaired mechanosensory function. We hypothesized that repair cSCs, which develop post injury, are an as‐yet‐untested cellular target for axonal regeneration.
Michael Li +6 more
wiley +1 more source
Emetic Action of Nitrogen Mustard (Mechlorethamine Hydrochloride) in Dogs and Cats
The early emetic response (within 4 hr.) after intravenous injection of the nitrogen mustard, methyl-bis (beta-chlorethyl) amine hydrochloride, was compared in dogs and cats.
H. L. Borison, R. K. Orkand, E. D. Brand
core +1 more source
Abstract Background Bacterial wilt of enset (Ensete ventricosum (Welw.) Cheesman) is a severe disease caused by Xanthomonas campestris pv. musacearum, resulting in complete crop failure and considerable damage. This study assessed the biochemical responses of two enset clones (one resistant and one susceptible) when inoculated with the pathogen and ...
Getahun Yemata, Masresha Fetene
wiley +1 more source

