Results 51 to 60 of about 8,282 (214)

Environmental Factors in the Relapse and Recurrence of Inflammatory Bowel Disease:A Review of the Literature [PDF]

open access: yes, 2015
The causes of relapse in patients with Crohn's disease (CD) and ulcerative colitis (UC) are largely unknown. This paper reviews the epidemiological and clinical data on how medications (non-steroidal anti-inflammatory drugs, estrogens and antibiotics ...
A Bitton   +99 more
core   +1 more source

Optimising hypoxia PET imaging and its applications in guiding targeted radiation therapy for non‐small cell lung cancer: a scoping review

open access: yesJournal of Medical Radiation Sciences, Volume 72, Issue 1, Page 106-118, March 2025.
This review article reports that quantification of hypoxic volumes using PET in the pre‐radiation therapy setting is of prognostic value and indicative of treatment response in non‐small cell lung cancer. Abstract Introduction Non‐small cell lung cancer (NSCLC) is the leading cause of cancer‐related death. Definitive treatment includes chemotherapy and
Carol Marks, Michelle Leech
wiley   +1 more source

Refractory Giardiasis in an Immunosuppressed Patient in Turkey

open access: yesJournal of Infection in Developing Countries, 2018
Giardiasis is an infection of the small intestine caused by the protozoan parasite Giardia duodenalis. In immunocompetent patients the infection is usually self-limited and no treatment may be needed.
Filiz Kaya   +4 more
doaj   +1 more source

Repositioning Antitubercular 6-Nitro-2,3-dihydroimidazo[2,1-b][1,3]oxazoles for Neglected Tropical Diseases: Structure-Activity Studies on a Preclinical Candidate for Visceral Leishmaniasis. [PDF]

open access: yes, 2016
6-Nitro-2,3-dihydroimidazo[2,1-b][1,3]oxazole derivatives were initially studied for tuberculosis within a backup program for the clinical trial agent pretomanid (PA-824).
Blaser, Adrian   +12 more
core   +3 more sources

f‐Block Element‐Based MOF Thin Films: A Platform for Luminescence, Sensing, and Energy Applications

open access: yesSmall, EarlyView.
f‐Block element–based metal–organic framework (f‐MOF) thin films offer exceptional potential for luminescent, sensing, and energy‐related applications. This review surveys recent progress in their synthesis, characterization, and functional implementation, emphasizing the diversity of available thin‐film fabrication strategies. The convergence of these
Dong‐Hui Chen, Christof Wöll
wiley   +1 more source

Creep in nitroimidazole inhibitory concentration among the Entamoeba histolytica isolates causing amoebic liver abscess and screening of andrographolide as a repurposing drug

open access: yesScientific Reports, 2023
Infections by Entamoeba histolytica (E. histolytica) lead to considerable morbidity and mortality worldwide and treatment is reliant on a single class of drugs, nitroimidazoles.
Aradhana Singh   +4 more
doaj   +1 more source

Activatable smart contrast agents for photoacoustic imaging

open access: yesSmart Molecules, EarlyView.
This review highlights recent advances in smart activatable photoacoustic imaging (PAI) contrast agents, which dynamically modulate their optical properties in response to external stimuli or microenvironmental cues. It discusses their molecular design, activation mechanisms, biomedical applications, and future prospects for clinically tailored use ...
Donghyeon Oh   +5 more
wiley   +1 more source

Long-Term Antibiotic Treatment for Crohn's Disease: Systematic Review and Meta-Analysis of Placebo-Controlled Trials [PDF]

open access: yes, 2017
Background. We investigated the effectiveness of long-term antibiotic treatment in patients with Crohn's disease. Methods. We performed a systematic review and meta-analysis of randomized clinical trials. Data sources were Medline (from 1966 through June
Egger, Matthias   +5 more
core  

Nitroimidazoles for imaging hypoxic myocardium

open access: yesJournal of Nuclear Cardiology, 1995
A series of radiopharmaceuticals that incorporate nitroimidazole moieties have been synthesized to detect decreased local tissue pO2. In contrast to agents that localize in proportion to perfusion, these agents concentrate in hypoxic tissue. Myocardium with an intracellular pO2 < 3 mm Hg (about 25% of normal), which has lost its contractile ability but
H W, Strauss, A, Nunn, K, Linder
openaire   +2 more sources

A structured, behavioural science approach to the preparation of antimicrobial stewardship interventions for companion animal veterinarians

open access: yesVeterinary Record, EarlyView.
Abstract Background A structured, behavioural science approach was adopted to develop antimicrobial stewardship interventions in UK first‐opinion companion animal veterinary practice. The objectives were to identify behavioural targets for intervention and to understand how practice contexts influence these behaviours.
Ben Walker   +3 more
wiley   +1 more source

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