Results 171 to 180 of about 12,240 (259)
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Bioorthogonal Reactions Utilizing Nitrones as Versatile Dipoles in Cycloaddition Reactions.
Chemical Reviews, 2021Bioorthogonal chemical reactions have emerged as convenient and rapid methods for incorporating unnatural functionality into living systems. Different prototype reactions have been optimized for use in biological settings.
D. A. Bilodeau +3 more
semanticscholar +1 more source
Journal of the American Chemical Society, 2021
Catalytic oxidative functionalization of alkynes has emerged as an effective method in synthetic chemistry in recent decades. However, enantioselective transformations via metal carbene intermediates are quite rare due to the lack of robust chiral ...
Su Zhou +5 more
semanticscholar +1 more source
Catalytic oxidative functionalization of alkynes has emerged as an effective method in synthetic chemistry in recent decades. However, enantioselective transformations via metal carbene intermediates are quite rare due to the lack of robust chiral ...
Su Zhou +5 more
semanticscholar +1 more source
Photoredox-Catalyzed Decarboxylative Cross-Coupling of α-Amino Acids with Nitrones.
Organic Letters, 2021A decarboxylative cross-coupling reaction of α-amino acids with nitrones via visible-light-induced photoredox catalysis has been established for easy access to β-amino hydroxylamines and vicinal diamines with structural diversity, which is featured with ...
Hengyuan Li +3 more
semanticscholar +1 more source
Angewandte Chemie, 2020
The regio- and enantioselective (3+3) cycloaddition of nitrones with 2-indolylmethanols was accomplished by the cooperative catalysis of hexafluoroisopropanol (HFIP) and chiral phosphoric acid (CPA).
Tian‐Zhen Li +7 more
semanticscholar +1 more source
The regio- and enantioselective (3+3) cycloaddition of nitrones with 2-indolylmethanols was accomplished by the cooperative catalysis of hexafluoroisopropanol (HFIP) and chiral phosphoric acid (CPA).
Tian‐Zhen Li +7 more
semanticscholar +1 more source
Recent Advances on Nitrones Design for Stroke Treatment.
Journal of Medicinal Chemistry, 2020The recent advances of tetramethylpyrazine nitrones and quinolylnitrones for the treatment of stroke have been reviewed and compared with other agents, showing promising therapeutic applications.
J. Marco-Contelles
semanticscholar +1 more source
Organic Letters, 2020
A Cu-catalyzed asymmetric ring-opening reaction of five-membered diaryliodonium salts and oximes is introduced. The reactions undergo selective N-arylation of oximes and provide an efficient protocol for the synthesis of atropisomeric nitrones.
Wenjing Guo, J. Gu, Z. Gu
semanticscholar +1 more source
A Cu-catalyzed asymmetric ring-opening reaction of five-membered diaryliodonium salts and oximes is introduced. The reactions undergo selective N-arylation of oximes and provide an efficient protocol for the synthesis of atropisomeric nitrones.
Wenjing Guo, J. Gu, Z. Gu
semanticscholar +1 more source
Journal of Organic Chemistry, 2020
New derivatives of α-phenyl-N-tert-butyl nitrone (PBN) bearing a hydroxyl, an acetate or an acetamide substituent on the N-tert-butyl moiety and para-substituted phenyl or naphthlyl moieties were synthesized.
Anaïs Deletraz +7 more
semanticscholar +1 more source
New derivatives of α-phenyl-N-tert-butyl nitrone (PBN) bearing a hydroxyl, an acetate or an acetamide substituent on the N-tert-butyl moiety and para-substituted phenyl or naphthlyl moieties were synthesized.
Anaïs Deletraz +7 more
semanticscholar +1 more source
Neuroprotective effects of novel nitrones: In vitro and in silico studies.
European Journal of Pharmacology, 2020Neurodegenerative diseases affect millions of people around the world. Several studies point out caspase-3 as a key player in the development and progression of neurological disorders including amyotrophic lateral sclerosis, Alzheimer's, Parkinson's and ...
Saira Cancela +4 more
semanticscholar +1 more source
Diverse Applications of Nitrones for the Synthesis of Heterocyclic Compounds
Asian Journal of Organic Chemistry, 2016Laura L Anderson
exaly +2 more sources