MicrobiologyOpen, Volume 14, Issue 4, August 2025.Porphyromonas gingivalis and Fusobacterium nucleatum (Fn) co‐infection increases PD‐L1 expression in esophageal cancer, aiding immune escape; eliminating them may reduce progression and recurrence. ABSTRACT Currently, the impact of the microbiome on the progression and recurrence of esophageal cancer remains unclear.
Xiayi Lin +6 more
wiley +1 more source
ChemistryOpen, Volume 14, Issue 8, August 2025.A novel series of hybrid 4‐(4‐benzoylpiperazin‐1‐yl)‐6‐nitroquinoline‐3‐carbonitrile derivatives has been designed, synthetized and evaluated for anticancer properties on the NCI60 panel. Strong antiproliferative effects have been detected against renal cancer cells.
Gabriele La Monica +4 more
wiley +1 more source
Wykorzystanie pochodnych aryloksylowych i reakcji chlorolizy w funkcjonalizacji 3,4-dipodstawionych 5- i 8-nitrochinolin [PDF]
, 2012 Wiodący zamysł mojej pracy dotyczył rozszerzenia dotychczasowych badań nad przekształceniem chinoliny poprzez tiochinantren 2a w 3,4-dipodstawione chinoliny 3 o możliwość otrzymania 5-, 6 - i 8-nitro-3,4-dipodstawionych chinolin 3, 8 , 9.
Chyćko, Magdalena
core
Detoxification of 4-nitroquinoline 1-oxide and benzo(a)pyrene-4,5-oxide by myristicin induced glutathione S-transferase in A/J mouse livers [PDF]
, 2000 The activities of mouse liver glutathione S-transferases (GSTs) induced by myristicin, the active compound in parsley leaf oil, against the carcinogens 4-nitroquinoline 1-oxide (4NQO) and benzo(a)pyrene-4,5-oxide (BP-4,5-oxide) were studied.
Saldivar, Eduardo
core +1 more source
Substitution in the aromatic series with special reference to nitration [PDF]
, 1937 The reactions between nitrogen pentoxide and, various organic compounds in different solvents have been examined. The results obtained in these nitrations have been compared to the results obtained by previous workers using different nitrating ...
Gordon, Stuart
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Mutation inp53 and de-regulation ofp53-related gene expression in three human cell lines immortalized with 4-nitroquinoline 1-oxide or60Co gamma rays [PDF]
, 1996 Mikio Itjima +5 more
openalex +1 more source
Acta Crystallographica Section E Structure Reports Online, 2005 The title compound, C9H6N2O3, is nearly planar, with maximum deviations from the mean plane of −0.024 (3) A for the C atom para to the ring N atom and 0.048 (2) A for one of the nitro O atoms. Three C—H⋯O and one N—H⋯O intermolecular hydrogen bonds stabilize the crystal structure.
Luiz Everson da Silva +3 more
openaire +1 more source
Diastereoselective Synthesis of Planar Chiral N-Substituted Ferrocenes Derived from Epimeric Imidazolones and their Application to Asymmetric Hydrogenation of Quinolines [PDF]
, 2015 This thesis describes the synthesis and use of an N-substituted ferrocene bearing a proline-derived chiral directing group and diastereoselective lithiation-electrophile quench of the pro-Sp hydrogen of the ferrocene to give planar chiral products in >95:
John, Joshni
core +1 more source
A fluorogenic hypoxia-activated prodrug strategy for targeted compound delivery and imaging of tumours [PDF]
, 2016 Hypoxia, a common feature in solid tumours, is associated with aggressive phenotypes, decreased genomic stability, and with increased resistance to all forms of cancer therapy.
O'Connor, Liam
core +1 more source
N-Benzyl-8-nitroquinolin-2-amine
Acta Crystallographica Section E Structure Reports Online, 2005 In the crystal structure of the title compound, C16H13N3O2, there are two independent L-shaped molecules in the asymmetric unit. No classical hydrogen bonds were found in the crystal structure.
Luiz Everson da Silva +3 more
openaire +1 more source