Results 61 to 70 of about 10,691 (139)
N-Nitrosodimethylamine Contamination in the Metformin Finished Products
A GC–MS/MS method with EI ionization was developed and validated to detect and quantify N-nitrosodimethylamine (NDMA) and seven other nitrosamines in 105 samples of metformin tablets from 13 different manufactures.
Adam Zmysłowski +2 more
doaj +1 more source
The effect of higher versus lower wattage e‐cigarettes on smoking: A randomized controlled trial
Abstract Aims To assess whether higher wattage e‐cigarettes (HWe), with improved nicotine delivery, enhance complete substitution compared with lower wattage e‐cigarettes (LWe) and whether complete switching lowers exposure to a cigarette‐derived lung carcinogen, using urinary 4‐(methylnitrosamino)‐1‐(3‐pyridyl)‐1‐butanol (NNAL) as a biomarker.
Yoo Jin Cho +8 more
wiley +1 more source
The Effect of Chlorhexidine Mouthwash on Blood Pressure: A Systematic Review and Meta‐Analysis
ABSTRACT Aim This study evaluated the effect of rinsing with a chlorhexidine containing mouthwash (CHX‐MW) on blood pressure (BP), as compared to rinsing with a control MW or no MW, based on (randomised) controlled trials and observational studies in humans. PROSPERO CRD42020222495.
Lars S. J. Toonen +5 more
wiley +1 more source
N-nitrosamines in 21th Century
Carcinogenic nitrogen compounds, N-nitrosamines, were first identified in beer and malt during the 70’s of twentieth century. Their proven occurrence in beer, in context with their significant health risk, led to the development of new technological ...
Tomáš Vrzal, Jana Olšovská
doaj +1 more source
Risk Assessment Models for Heated Tobacco Products
ABSTRACT Heated tobacco products (HTPs) are marketed as alternatives to conventional cigarettes with a potential reduced risk profile. Yet, their actual impact on cancer and noncancer disease risk remains uncertain and requires rigorous quantitative assessment.
Lucia Maddalena +3 more
wiley +1 more source
The present study investigates the influence of nitrosamines and etoposide on mesenchymal stromal cells (MSCs) in a differentiation state- and biological age-dependent manner.
Meryem Ouzin +3 more
doaj +1 more source
N-nitrosamines and nitrosamine drug substance related impurities (NDSRIs) became a critical topic for the development and safety of small molecule medicines following the withdrawal of various pharmaceutical products from the market.
Andreas H. Göller +3 more
doaj +1 more source
What's new? While the association between tobacco consumption and oral cancer is well established, the effect of cessation, particularly of chewing tobacco, the most common tobacco product in South Asia, is understudied. This case–control study in an Indian population demonstrates that a longer duration of tobacco smoking and chewing cessation is ...
Gayathri B. Pullat +8 more
wiley +1 more source
Drug-mediated nitrosogenesis or oncopharmacogenesis of skin cancer in general and melanoma skin cancer development in particular could be pathogenetically determined/explained by the presence of photocarcinogens in drugs.
Tchernev G., Kordeva S.
doaj +1 more source
The aim of the present study was the evaluation of nitrate, nitrite, nitrosodiethylamine (NDEA) and nitrosodimethylamine (NDMA) intake by food consumption.
Liliana Avasilcai +3 more
doaj +1 more source

