Results 61 to 70 of about 10,691 (139)

N-Nitrosodimethylamine Contamination in the Metformin Finished Products

open access: yesMolecules, 2020
A GC–MS/MS method with EI ionization was developed and validated to detect and quantify N-nitrosodimethylamine (NDMA) and seven other nitrosamines in 105 samples of metformin tablets from 13 different manufactures.
Adam Zmysłowski   +2 more
doaj   +1 more source

The effect of higher versus lower wattage e‐cigarettes on smoking: A randomized controlled trial

open access: yesAddiction, Volume 121, Issue 8, Page 2186-2196, August 2026.
Abstract Aims To assess whether higher wattage e‐cigarettes (HWe), with improved nicotine delivery, enhance complete substitution compared with lower wattage e‐cigarettes (LWe) and whether complete switching lowers exposure to a cigarette‐derived lung carcinogen, using urinary 4‐(methylnitrosamino)‐1‐(3‐pyridyl)‐1‐butanol (NNAL) as a biomarker.
Yoo Jin Cho   +8 more
wiley   +1 more source

The Effect of Chlorhexidine Mouthwash on Blood Pressure: A Systematic Review and Meta‐Analysis

open access: yesInternational Journal of Dental Hygiene, Volume 24, Issue 3, Page 390-403, August 2026.
ABSTRACT Aim This study evaluated the effect of rinsing with a chlorhexidine containing mouthwash (CHX‐MW) on blood pressure (BP), as compared to rinsing with a control MW or no MW, based on (randomised) controlled trials and observational studies in humans. PROSPERO CRD42020222495.
Lars S. J. Toonen   +5 more
wiley   +1 more source

N-nitrosamines in 21th Century

open access: yesKvasný průmysl, 2016
Carcinogenic nitrogen compounds, N-nitrosamines, were first identified in beer and malt during the 70’s of twentieth century. Their proven occurrence in beer, in context with their significant health risk, led to the development of new technological ...
Tomáš Vrzal, Jana Olšovská
doaj   +1 more source

Risk Assessment Models for Heated Tobacco Products

open access: yesRisk Analysis, Volume 46, Issue 8, August 2026.
ABSTRACT Heated tobacco products (HTPs) are marketed as alternatives to conventional cigarettes with a potential reduced risk profile. Yet, their actual impact on cancer and noncancer disease risk remains uncertain and requires rigorous quantitative assessment.
Lucia Maddalena   +3 more
wiley   +1 more source

Evaluation of Genotoxic Effects of N-Methyl-N-Nitroso-Urea and Etoposide on the Differentiation Potential of MSCs from Umbilical Cord Blood and Bone Marrow

open access: yesCells
The present study investigates the influence of nitrosamines and etoposide on mesenchymal stromal cells (MSCs) in a differentiation state- and biological age-dependent manner.
Meryem Ouzin   +3 more
doaj   +1 more source

Quantum chemical calculations of nitrosamine activation and deactivation pathways for carcinogenicity risk assessment

open access: yesFrontiers in Pharmacology
N-nitrosamines and nitrosamine drug substance related impurities (NDSRIs) became a critical topic for the development and safety of small molecule medicines following the withdrawal of various pharmaceutical products from the market.
Andreas H. Göller   +3 more
doaj   +1 more source

The impact of tobacco cessation on buccal mucosa cancer risk: A multi‐centre case–control study in India

open access: yesInternational Journal of Cancer, Volume 159, Issue 2, Page 368-377, 15 July 2026.
What's new? While the association between tobacco consumption and oral cancer is well established, the effect of cessation, particularly of chewing tobacco, the most common tobacco product in South Asia, is understudied. This case–control study in an Indian population demonstrates that a longer duration of tobacco smoking and chewing cessation is ...
Gayathri B. Pullat   +8 more
wiley   +1 more source

Melanoma in Situ and Phototoxic Drug Reaction Appearing Simultaneously after Antihypertensives Intake: Photo Nitroso Carcinogenicity of Drugs as Possible Risk Factor for the Development and Progression of Cutaneous Melanoma

open access: yesActa Medica Bulgarica
Drug-mediated nitrosogenesis or oncopharmacogenesis of skin cancer in general and melanoma skin cancer development in particular could be pathogenetically determined/explained by the presence of photocarcinogens in drugs.
Tchernev G., Kordeva S.
doaj   +1 more source

Evaluation of the Intake of Nitrate, Nitrite, Nitrosodiethylamine and Nitrosodimethylamine by Food Consumption

open access: yesEQA, 2014
The aim of the present study was the evaluation of nitrate, nitrite, nitrosodiethylamine (NDEA) and nitrosodimethylamine (NDMA) intake by food consumption.
Liliana Avasilcai   +3 more
doaj   +1 more source

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