Results 151 to 160 of about 3,155 (190)

Salidroside Selectively Binds to SEC23A and Ameliorates Psychological Stress-Induced Hyperpigmentation. [PDF]

Pharmaceuticals (Basel)
Yang M, Sun X, Wang D, Nie H, Cheng K, Gu J, Chen L, Zhang Y, Yang L, Katayama I, Li Y, Wu H.   +11 more
europepmc   +1 more source

The role of substance P in Th17/Treg imbalance and ocular surface damage in chronic allergic conjunctivitis. [PDF]

J Transl Med
Bao J, Wen Y, Wu B, Li Y, Li S, Lei F, Tian L, Chen X, Jie Y.   +8 more
europepmc   +1 more source

On the Study of Botulinum Toxin A Actions: Beyond the Neuromodulation Induced by SNAP-25 Cleavage. [PDF]

Toxins (Basel)
Rasetti-Escargueil C, Palea S.
europepmc   +1 more source

The neuroimmune axis in breast cancer: from mechanistic insights to clinical applications. [PDF]

BMC Med
Wu Y, Zhang K, Xia X, Zhang T, Jiang N, Zhang Y, Zheng F, Jiang Y, Xiang X, Miao H, Tang H, Ren S, Li MY.   +12 more
europepmc   +1 more source

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NK1R/5-HT1AR Interaction Is Related to the Regulation of Melanogenesis

FASEB Journal, 2018
ABSTRACT Substance P (SP) is a candidate mediator along the brain–skin axis and can mimic the effects of stress to regulate melanogenesis. Previously, we and others have found that the regulation of SP for pigmentary function was mediated by neurokinin 1 receptor (NK1R).
Ling He, Xiaohong An, Minxuan Cai
exaly   +3 more sources

Generation of a Transgenic Model to Address Regulation and Function of the Human Neurokinin 1 Receptor (NK1R)

Neuropeptides, 2007
We have generated mouse transgenic lines using yeast artificial chromosome (YAC) technology which demonstrate expression from the human NK1 receptor (NK1R) locus. We introduced a 380 kb fragment encompassing the human NK1R gene and flanking regions which we hoped would recapitulate the expected endogenous expression of the human gene. To visualise this
John P Quinn, J P Quinn, V J Bubb
exaly   +3 more sources

Nuclear Localization of SP, CGRP, and NK1R in a Subpopulation of Dorsal Root Ganglia Subpopulation Cells in Rats

Cellular and Molecular Neurobiology, 2006
Signals generated by renal pelvic afferent nerves in response to stimulation are transmitted from peripheral processes of dorsal root ganglia neurons to their central terminals in the dorsal horn of the spinal cord to cause the release of neuropeptides, including SP and CGRP.
Patrícia Aline, Boer, José Antonio Rocha, Gontijo   +1 more
openaire   +3 more sources

Personalised targeting of the substance P/NK1R axis in pancreatic ductal adenocarcinoma [PDF]

Background: The Neurokinin-1 receptor (NK1R) represents a promising target for pancreatic ductal adenocarcinoma (PDAC) therapy. Yet its complex ex-pression patterns and functional implications remain incompletely understood. Methods: A comprehensive multi-method approach was employed to investi-gate NK1R biology in PDAC, including transcriptomic ...
Ittermann, Iris
core   +3 more sources

Upregulated Expression of Substance P (SP) and NK1R in Eczema and SP-Induced Mast Cell Accumulation

Cell Biology and Toxicology, 2017
Substance P (SP) was reported to be associated with eczema and acts as a potent skin mast cell secretagogue. However, little is known of its expression in inflammatory cells in eczema and its ability in induction of mast cell accumulation. In the present study, we investigated expression of SP and neurokinin-1 receptor (NK1R) on peripheral blood ...
Junling Wang, Qijun Jiang, Huiyun Zhang
exaly   +3 more sources