Results 171 to 180 of about 3,155 (190)
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Cancer Research
Abstract Background: The neurokinin-1 receptor (NK1R) complex, activated by Substance P (SP), has emerged as a promising target. SP promotes cell growth, whereas its antagonist, Aprepitant (AP), used clinically for chemotherapy-induced nausea, has demonstrated anti-tumor activity.
Matthias Ilmer +4 more
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Abstract Background: The neurokinin-1 receptor (NK1R) complex, activated by Substance P (SP), has emerged as a promising target. SP promotes cell growth, whereas its antagonist, Aprepitant (AP), used clinically for chemotherapy-induced nausea, has demonstrated anti-tumor activity.
Matthias Ilmer +4 more
openaire +1 more source
NK1R as a therapeutic target in hepatoblastoma
Klinische Pädiatrie, 2015A Garnier +4 more
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Naunyn-Schmiedeberg's Archives of Pharmacology
Substance P (SP), an important neuropeptide, has a crucial role in the progression of several cancers, including prostate cancer, through interacting with the neurokinin-1 receptor (NK1R). Oxidative stress is also involved in the onset and progression of prostate cancer.
Sara Zarei Shandiz +4 more
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Substance P (SP), an important neuropeptide, has a crucial role in the progression of several cancers, including prostate cancer, through interacting with the neurokinin-1 receptor (NK1R). Oxidative stress is also involved in the onset and progression of prostate cancer.
Sara Zarei Shandiz +4 more
openaire +2 more sources
Benefits and Harms of NK1R Antagonists in Pruritus: A Systematic Review and Meta-Analysis
Dermatologic Therapy, 2021Xian Jiang, Yin Liu, Linghong Guo
exaly
[55Co]Co-DOTA-SP4: Towards NK1R-targeted Theranostics of Glioblastoma
Nuclear Medicine and Biology, 2023Vigga Laursen +10 more
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Heterologous desensitization and trafficking of neurokinin 1 and 3 receptors (NK1R, NK3R)
Gastroenterology, 2000Oliver Dery +3 more
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