Results 121 to 130 of about 582,983 (289)

Inhibition of TIGIT on NK cells improves their cytotoxicity and HIV reservoir eradication potential

mBio
The latent human immunodeficiency virus (HIV) reservoir presents the biggest obstacle to curing HIV chronic infection. Consequently, finding novel strategies to control the HIV reservoir is critical.
Yue Wang, Yidi Li, Jiaqi Chen, Chenxi Guo, Xiaowen Yu, Zining Zhang, Yajing Fu, Xiaoxu Han, Qinghai Hu, Haibo Ding, Hong Shang, Yongjun Jiang   +11 more
doaj   +1 more source

Aggressive NK-Cell Leukemia [PDF]

Frontiers in Pediatrics, 2018
Aggressive NK cell leukemia (ANKL) is a rare malignant lymphoproliferative disorder of mature NK cells closely associated with Epstein-Barr virus (EBV) and more common in East Asia than in other areas. Significant variations exist in the morphology of ANKL tumor cells, from typical large granular lymphocyte morphology to highly atypical features with ...
openaire   +3 more sources

Cognitive Behavioral Therapy for Youth with Childhood‐Onset Lupus: A Randomized Clinical Trial

Arthritis Care &Research, Accepted Article.
Objective Our objective was to determine the feasibility and acceptability of the Treatment and Education Approach for Childhood‐onset Lupus (TEACH), a six‐session cognitive behavioral intervention addressing depressive, fatigue, and pain symptoms, delivered remotely to individual youth with lupus by a trained interventionist.
Natoshia R. Cunningham, Thea Senger‐Carpenter, Jocelyn Zuckerman, Michelle Adler, Mallet R. Reid, Ashley Danguecan, Luana Flores Pereira, Sarah I. Mossad, Samantha L. Ely, Khalid Abulaban, Elizabeth A. Kessler, Natalie Rosenwasser, Tamar B. Rubinstein, Ekemini A. Ogbu, Emily A. Smitherman, Alaina Miller, Taylor Abounader, Elizabeth Ross, Livie Timmerman, Dhriti Sharma, Jennifer N. Stinson, Stacy Allen, Kabita Nanda, Tala El Tal, Deborah M. Levy, Linda T. Hiraki, Hermine I. Brunner, Mathew Reeves, Steven J. Pierce, Andrea Knight   +29 more
wiley   +1 more source

MACC1 facilitates the escape of nasopharyngeal carcinoma cells from killing by natural killer cells

Biotechnology & Biotechnological Equipment, 2019
This study examined the regulation of phenotype and function of natural killer (NK) cells by nasopharyngeal carcinoma (NPC) cells with metastasis-associated in colon cancer-1 (MACC1) overexpression.
Chong Zhao, Yuehua Liu, Zhuoping Liang, Huajun Feng, Sheng’en Xu   +4 more
doaj   +1 more source

Associations of Sleep and Shift Work with Osteoarthritis Risk

Arthritis Care &Research, Accepted Article.
Objective Daily rhythms may be critical for maintaining homeostasis of joint tissues. We aimed to investigate the relationships between circadian clock disruption, sleep, and osteoarthritis (OA) risk in humans. Methods In the UK Biobank, a prospective 500,000‐person cohort, we evaluated associations between sleep duration, sleeplessness/insomnia, and ...
Elizabeth L. Yanik, Abigail Bridgeman, Erik D. Herzog, Vy Pham, Bradley A. Evanoff, Farshid Guilak   +5 more
wiley   +1 more source

Targeted immune cell therapy for hepatocellular carcinoma using expanded liver mononuclear cell-derived natural killer cells

Neoplasia: An International Journal for Oncology Research
Natural killer (NK) cells are a promising cellular therapy for T cell-refractory cancers but are frequently deficient or dysfunctional in patients with hepatocellular carcinoma (HCC).
Xin Hu, Yifang Shui, Seiichi Shimizu, Seisuke Sakamoto, Mureo Kasahara, Seiji Okada, Wen-Zhi Guo, Masayuki Fujino, Xiao-Kang Li   +8 more
doaj   +1 more source

Interleukin 2 activation of natural killer cells rapidly induces the expression and phosphorylation of the Leu-23 activation antigen. [PDF]

, 1988
IL-2 potentiates both growth and cytotoxic function of T lymphocytes and NK cells. Resting peripheral blood NK cells can respond directly to rIL-2, without requirement for accessory cells or cofactors, and enhanced cytotoxicity can be measured within a ...
Barney, C, Buck, DW, Ding, A, Evans, E, Lanier, LL, Phillips, JH, Rhodes, L   +6 more
core  

Nitride‐Reinforced Metal Matrix Nanocomposite Powders Production by Plasma‐Assisted Thermochemical Treatment of Intermetallic Powders

Advanced Engineering Materials, EarlyView.
This study proposes a new methodology for producing metal matrix nanocomposites in the solid state. The process involves the plasma‐assisted thermochemical treatment of metallic alloy powders. As a proof‐of‐concept, TiN nanoparticles are synthesized directly on the surface of FeTi intermetallic powder particles, enabling the development of the ...
Deivison Daros Paim, Antônio Rogério de Souza, Tatiana Bendo, Aloisio Nelmo Klein, Rodrigo Perito Cardoso   +4 more
wiley   +1 more source

Effect of Vasoactive Intestinal Peptide (VIP) on NKG2D Signal Pathway and Its Contribution to Immune Escape of MKN45 Cells

The Scientific World Journal, 2013
Objective. To investigate VIP effect on the cytotoxicity of NK cell to gastric cancer cells in vitro and the relation between the effect with the NKG2D signal molecules in NK cells. Material and Methods.
Chong Wang, Xi-Jin Zhou, Yuan-yuan Li, Juan Wan, Le-ying Yang, Guo-Hua Li   +5 more
doaj   +1 more source

Single Pair of Weyl Points Evolve From Spin Group‐Protected Nodal Line in Half‐Metallic Ferromagnet V3S4

Advanced Functional Materials, EarlyView.
A spin group (SG)‐based mechanism is proposed to realize a single pair of Weyl points. PT‐symmetric nodal lines (NLs) persist under T‐breaking, protected by the combination of SG and P symmetry. When considering spin‐orbit coupling, the SG‐protected NL will split into Weyl points, which will also induce anomalous transport phenomena arising from ...
Shifeng Qian, Yao Zhang, Xiaowei Sheng, Xiuxian Yang, Gang Zhang, Junfeng Gao, Xiaotian Wang   +6 more
wiley   +1 more source