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Genome-Wide Identification and Functional Evolution of NLR Gene Family in Capsicum annuum [PDF]

Current Issues in Molecular Biology
Capsicum annuum (pepper) is a globally significant Solanaceous crop vulnerable to devastating pathogens such as Phytophthora capsici. Nucleotide-binding leucine-rich repeat (NLRs) proteins are crucial intracellular immune receptors mediating effector ...
Chong Feng, Qi Chen, Wenhao Liu, Tengfei Li, Tuo Ji   +4 more
doaj   +6 more sources

Posttranslational Regulation of the NLR Family Pyrin Domain-Containing 3 Inflammasome [PDF]

Frontiers in Immunology, 2018
The NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome is a multi-protein complex that can be activated by a variety of pathogen-associated molecular patterns or damage-associated molecular patterns.
Do-Wan Shim, Kwang-Ho Lee, Kwang-Ho Lee
doaj   +5 more sources

Fine dissection of limber pine resistance to Cronartium ribicola using targeted sequencing of the NLR family [PDF]

BMC Genomics, 2021
Background Proteins with nucleotide binding site (NBS) and leucine-rich repeat (LRR) domains (NLR) make up one of most important resistance (R) families for plants to resist attacks from various pathogens and pests. The available transcriptomes of limber
Jun-Jun Liu, Anna W. Schoettle, Richard A. Sniezko, Holly Williams, Arezoo Zamany, Benjamin Rancourt   +5 more
doaj   +2 more sources

Jiedutongluotiaogan Formula Improves Pancreatic Dysfunction in db/db Mice through Modulating the Gut Microbiota-Short Chain Fatty Acids-NLR Family, Pyrin Domain–Containing Protein 3 Inflammasome

World Journal of Traditional Chinese Medicine
Objective: Disturbance of gut microbiota plays an essential role in metabolic diseases, such as diabetes. Jiedutongluotiaogan formula (JTTF) was designed to meliorate the symptoms of type 2 diabetes.
Jin-Li Luo, Wen-Qi Jin, Li Wang, Qi Zhang, Yu Wang, Cui Wu, Yue Qu, Yu-Ting Peng, Li-Wei Sun, Chun-Li Piao   +9 more
doaj   +2 more sources

The NLR family pyrin domain containing 3 inflammasome in the mechanism of electroacupuncture: Current status and future perspectives. [PDF]

Front Aging Neurosci, 2022
Yuan M, Wang D, Yang J, Lan H.
europepmc   +3 more sources

Macroevolution of NLR genes in family Fabaceae provides evidence of clade specific expansion and contraction of NLRome in Vicioid clade

Plant Stress, 2023
Whole genome duplication plays a significant role in plant genome evolution by providing raw materials that can be modified by natural or artificial selection.
Fatima Qureshi, Amna Mehmood, Shahid Ali Khan, Muhammad Bilal, Fatima Urooj, Mehreen Alyas, Jaweria Ijaz, Muhammad Zain, Fatima Noreen, Shamiza Rani, Shahid Fareed, Fozia Saleem, Wasba Sarfraz, Sidra Shakoor, Romana Iftikhar, Amna Areej, Saad Serfraz   +16 more
doaj   +2 more sources

Molecular Evolution of the NLR Gene Family Reveals Diverse Innate Immune Strategies in Bats [PDF]

Biomolecules
Bats, as the world’s second-largest mammalian order, have garnered significant attention for their ability to harbor numerous viruses without exhibiting disease symptoms.
Gang Liu, Fujie Han, Xinya Guo, Liya Yang, Nishan Du, Xue Zhao, Chen Zhang, Jie Peng, Kangkang Zhang, Jiang Feng, Ying Liu   +10 more
doaj   +2 more sources

AR-A014418, a glycogen synthase kinase-3β inhibitor, mitigates lipopolysaccharide-induced inflammation in rat dental pulp stem cells via NLR family pyrin domain containing 3 inflammasome impairment. [PDF]

J Dent Sci, 2023
Xie H, Lin Y, Fang F.
europepmc   +2 more sources

Didymin, a natural flavonoid, relieves the progression of myocardial infarction via inhibiting the NLR family pyrin domain containing 3 inflammasome. [PDF]

Pharm Biol, 2022
Zhang Y, RuXian G.
europepmc   +2 more sources

Overexpressed CD39 mitigates sepsis‑induced kidney epithelial cell injury via suppressing the activation of NLR family pyrin domain containing 3. [PDF]

Int J Mol Med, 2019
Yang M, Lu L, Kang Z, Ma T, Wang Y.
europepmc   +3 more sources