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Evolution of the NLR gene family in vertebrates: insights into the origin of inflammasomes.
Nucleotide binding domain leucine rich repeat proteins (NLRs) are a family of intracellular pattern recognition receptors which play an important role in innate immune system; as well as the regulation of many other immunity-related components and signalling pathways, such as MHCs, NF-Κβ, pyroptosis, inflammasomes or MAPK (Chou et al., 2023; Hansen et ...Pardo-Velasco, Rafael J. +3 more
openaire +1 more source
NLR members NLRC4 and NLRP3 mediate sterile inflammasome activation in microglia and astrocytes
Journal of Experimental Medicine, 2017Haitao Guo, Jenny Ting, Sushmita Jha
exaly
The NLR (NBD-LRR containing) Family of Intracellular Sensors in Inflammation and Immune Response.
Blood, 2009exaly

