Results 231 to 240 of about 87,795 (274)

Zinc‐Coordination‐Driven Pyroptosis Nano‐Inductor Sensitizes Colorectal Cancer Chemo‐Immunotherapy by Specific Delivery and Cell Stemness Suppression

MedComm – Oncology, Volume 5, Issue 2, June 2026.
CD44‐targeted CNPs co‐deliver Zn2+ and MIT–ALA to CRC cells. Intracellularly, Zn2+ inhibits GLUT1‐dependent glycolysis, and ALA disrupts mitochondrial function, driving metabolic exhaustion in CSCs. This mitochondrial damage primes GSDMD‐mediated pyroptosis, accompanied by the release of pro‐inflammatory cytokines (IL‑1β, IL‑18).
Qinxia Chang, Wenting Cheng, Hailong Tian, Siyuan Qin, Yaying Zhang, Jing Zuo, Wenbing Pu, Shuaijun Lu, Na Xie   +8 more
wiley   +1 more source

Wheat's war against stripe rust: Integrating host immunity, genomics and breeding for durable resistance

The Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Wheat (Triticum aestivum L.), a foundation of global food security, faces persistent threats from stripe rust caused by Puccinia striiformis f. sp. tritici (Pst). The pathogen thrives in cool and humid environments and regularly causes epidemics that lead to severe yield losses.
Farkhandah Jan, Mukesh Rathore, Dinesh Kumar Saini, Ayushi Singh, Naeela Qureshi, Nikita Aggarwal, Mahpara Bashir, Mehnaz Shakeel, Vikas Gupta, Sundeep Kumar, Rajeev Kumar Varshney, Reyazul Rouf Mir   +11 more
wiley   +1 more source

Polarity program control by NLR family genes.

openaire   +1 more source

Identification of resistance sources and genomic regions regulating spot blotch resistance in Asian bread wheat (Triticum aestivum L.) via genome‐wide association study

The Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Spot blotch (SB), caused by Bipolaris sorokiniana, is a major yield‐limiting disease of wheat (Triticum aestivum L.) in the warm, humid agroclimatic zones of South Asia. The development of resistant cultivars through molecular approaches offers a sustainable strategy for managing this disease.
Nikita Aggarwal, Xinyao He, Mukesh Rathore, Farkhandah Jan, Vikas Gupta, Reyazul Rouf Mir, Pawan K. Singh   +6 more
wiley   +1 more source

Integrative genomic analyses reveal candidate genes for the Ur‐3 and Ur‐7 rust resistance loci in common bean

The Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Bean rust, caused by Uromyces appendiculatus, severely limits the productivity of common bean (Phaseolus vulgaris L.), an essential source of protein and micronutrients in human diets worldwide. Durable disease management relies primarily on host resistance; however, the molecular architecture of several key rust resistance loci remains ...
Alvaro Soler‐Garzón, Giseli Valentini, Marcial Pastor‐Corrales, Ruifeng He, Phillip N. Miklas   +4 more
wiley   +1 more source

Systemic inflammatory biomarkers and their partial role in the association between diabetes and sarcopenia: A population-based study using NHANES data. [PDF]

Medicine (Baltimore)
Qin J, Qiu X, Liang B, Chen Y, Jiang T.
europepmc   +1 more source

Pan‐NLRome analysis uncovers genetic diversity and evolutionary dynamics among rice, maize and sorghum

The Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Nucleotide‐binding leucine‐rich repeat (NLR) genes constitute one of the largest families of plant immune receptors and are central to crop disease resistance. Rice (Oryza sativa L.), maize (Zea mays L.), and sorghum (Sorghum bicolor (L.) Moench) are major crops underpinning global food security, and enhancing their immunity is critical for ...
Yanbo Wang, Tashi Dorjee, Yinzi Wang, Di Peng, Lang Chen, Chuanzheng Wei, Shichao Sun, Mingyu Duan, Hui Li, Adrian Hathorn, Emma Mace, David Jordan, Xun Wu, Xiaocui Chen, Yongfu Tao   +14 more
wiley   +1 more source

Evaluation of the Systemic Inflammatory Landscape and C1q/TNF-Related Protein Profiles in Facial Paralysis. [PDF]

Curr Issues Mol Biol
Bilgin E, Baklacı D, Çandar T.
europepmc   +1 more source

Advances in gene cloning and functional genomics approaches for wheat (Triticum aestivum L.) improvement

The Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Wheat (Triticum aestivum L.) is a globally important cereal crop which provides ∼20% calories in human diet. Identifying genes and elucidating their functions is still challenging in wheat due to its large genome (∼16 Gb) with significant amount of repetitive elements.
Santosh Gudi, Khizar Razzaq, Jatinder Singh, Luis Del Rio Mendoza, Mohamed Khan, Rajeev Gupta, Upinder Gill   +6 more
wiley   +1 more source

Association Between Neutrophil-to-Lymphocyte Ratio and Vitamin D Deficiency in Patients With Sickle Cell Disease: A Cross-Sectional Study in Central Uganda. [PDF]

Cureus
Muwanguzi E, Tumusiime J, Salamu G, Nkubi Bagenda C, Okongo B.   +4 more
europepmc   +1 more source