Results 211 to 220 of about 87,795 (274)

Effects of Total Flavonoids From Rubus chingii Hu on the Hypothalamic–Pituitary–Ovarian Axis and Inflammatory Response in Polycystic Ovary Syndrome Rats

open access: yesFood Science &Nutrition, Volume 14, Issue 6, June 2026.
RHF improves sex hormone secretion imbalance, restores the estrous cycle, inhibits ovarian hyperplasia and pathology, and reduces systemic and local ovarian inflammation in PCOS rats via enhancing HPO axis function and suppressing NLRP3 inflammasome signaling pathway activation.
Mengfan Peng   +7 more
wiley   +1 more source

Dietary Index for Gut Microbiota and the Odds of Metabolic Dysfunction‐Associated Fatty Liver Disease in Overweight and Obese Children and Adolescents: A Cross‐Sectional Study

open access: yesHealth Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aims Metabolic dysfunction‐associated fatty liver disease (MAFLD) is increasingly prevalent among children and adolescents with overweight or obesity, posing a growing public health challenge. Emerging evidence highlights the gut microbiota as a critical mediator in MAFLD pathogenesis, yet few studies have explored dietary ...
Farzam Kamrani   +5 more
wiley   +1 more source

Systemic Inflammation and Central Neuronal Damage: The Relationship Between Neutrophil‐to‐Lymphocyte Ratio and Neuron‐Specific Enolase in Acute Ischemic Stroke

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 6, June 2026.
ABSTRACT Background and Purpose The systemic inflammatory response, quantified by the neutrophil‐to‐lymphocyte ratio (NLR), and central neuronal injury, reflected by serum neuron‐specific enolase (NSE), are implicated in the pathogenesis of acute ischemic stroke (AIS).
Ning Rong   +8 more
wiley   +1 more source

Cannabidiol Protects Against 1‐Methyl‐4‐Phenylpyridinium and Manganese‐Induced Neurotoxicity via Nod‐Like Receptor Protein 3 Inflammasome Suppression

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 6, June 2026.
CBD oil exhibits neuroprotective effects in Parkinson's disease models by inhibiting NLRP3 inflammasome activation. It preserves dopamine levels and reduces α‐synuclein accumulation, suggesting its potential as a therapeutic strategy against neuroinflammation and neurodegeneration.
Göksun Demirel   +7 more
wiley   +1 more source

Association Between Multi‐Laboratory Parameters Pre‐ and Post‐Treatment and Pathological Features and Their Values in Clinical Decision in Primary Hepatic Carcinoma

open access: yesJournal of Clinical Laboratory Analysis, Volume 40, Issue 11, June 2026.
Primary hepatic cancer (PHC), especially hepatocellular carcinoma (HCC), is still a significant burden worldwide. The efficacy of diagnosis, treatment response monitoring, and prognostication using laboratory biomarkers is still a challenge. This study analyzed multi‐laboratory parameters pre‐ and post‐treatment and their associations with clinical and
Xiaowei Chi   +3 more
wiley   +1 more source

Extracellular Vesicles Released by Picornavirus‐Infected Cells Modify Antiviral Immune Cell Responses

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
ABSTRACT Naked viruses of the family Picornaviridae commonly spread via lysis of infected cells. Recent studies indicate that, prior to cell lysis, naked viruses are packaged and released inside extracellular vesicles (EVs). This has been considered a pro‐viral mechanism because EV membranes protect enclosed virions from neutralizing antibodies.
Xinyi Pei   +9 more
wiley   +1 more source

Serum Histatin Levels in COVID‐19: Association With Disease Severity and Immune Status

open access: yesJournal of Medical Virology, Volume 98, Issue 6, June 2026.
ABSTRACT Histatins are histidine‐rich antimicrobial peptides with emerging immunomodulatory properties; however, their systemic behavior across the clinical spectrum of COVID‐19 remains unknown. We aimed to characterize serum histatin levels in patients with mild COVID‐19 (without pneumonia) and severe COVID‐19 (with pneumonia) and to explore factors ...
Umut Aydın   +3 more
wiley   +1 more source

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