Results 211 to 220 of about 87,795 (274)
RHF improves sex hormone secretion imbalance, restores the estrous cycle, inhibits ovarian hyperplasia and pathology, and reduces systemic and local ovarian inflammation in PCOS rats via enhancing HPO axis function and suppressing NLRP3 inflammasome signaling pathway activation.
Mengfan Peng +7 more
wiley +1 more source
Overexpressed CD39 mitigates sepsis‑induced kidney epithelial cell injury via suppressing the activation of NLR family pyrin domain containing 3. [PDF]
Yang M, Lu L, Kang Z, Ma T, Wang Y.
europepmc +1 more source
NLR family pyrin domain containing 3 (NLRP3; NALP3) [PDF]
openaire +1 more source
ABSTRACT Background and Aims Metabolic dysfunction‐associated fatty liver disease (MAFLD) is increasingly prevalent among children and adolescents with overweight or obesity, posing a growing public health challenge. Emerging evidence highlights the gut microbiota as a critical mediator in MAFLD pathogenesis, yet few studies have explored dietary ...
Farzam Kamrani +5 more
wiley +1 more source
ABSTRACT Background and Purpose The systemic inflammatory response, quantified by the neutrophil‐to‐lymphocyte ratio (NLR), and central neuronal injury, reflected by serum neuron‐specific enolase (NSE), are implicated in the pathogenesis of acute ischemic stroke (AIS).
Ning Rong +8 more
wiley +1 more source
CBD oil exhibits neuroprotective effects in Parkinson's disease models by inhibiting NLRP3 inflammasome activation. It preserves dopamine levels and reduces α‐synuclein accumulation, suggesting its potential as a therapeutic strategy against neuroinflammation and neurodegeneration.
Göksun Demirel +7 more
wiley +1 more source
Primary hepatic cancer (PHC), especially hepatocellular carcinoma (HCC), is still a significant burden worldwide. The efficacy of diagnosis, treatment response monitoring, and prognostication using laboratory biomarkers is still a challenge. This study analyzed multi‐laboratory parameters pre‐ and post‐treatment and their associations with clinical and
Xiaowei Chi +3 more
wiley +1 more source
NLR family pyrin domain containing 12 (NLRP12; NALP12) [PDF]
openaire +1 more source
ABSTRACT Naked viruses of the family Picornaviridae commonly spread via lysis of infected cells. Recent studies indicate that, prior to cell lysis, naked viruses are packaged and released inside extracellular vesicles (EVs). This has been considered a pro‐viral mechanism because EV membranes protect enclosed virions from neutralizing antibodies.
Xinyi Pei +9 more
wiley +1 more source
Serum Histatin Levels in COVID‐19: Association With Disease Severity and Immune Status
ABSTRACT Histatins are histidine‐rich antimicrobial peptides with emerging immunomodulatory properties; however, their systemic behavior across the clinical spectrum of COVID‐19 remains unknown. We aimed to characterize serum histatin levels in patients with mild COVID‐19 (without pneumonia) and severe COVID‐19 (with pneumonia) and to explore factors ...
Umut Aydın +3 more
wiley +1 more source

