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NLR, the nucleotide-binding domain leucine-rich repeat containing gene family
Current Opinion in Immunology, 2008The NLR (nucleotide-binding domain leucine-rich repeat containing) family is found in plants and animals, and serves as crucial regulators of inflammatory and innate immune response, though its functions are likely to extend greatly beyond innate immunity, and even beyond the immune system.
Zhengmao, Ye, Jenny Pan-Yun, Ting
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NLR regulation of the TSC family.
Both NOD2 and NLRC4 could influence or control expression of TSC22D nutrient sensor genes including control of TSC22D4 by NOD2.openaire +1 more source
The NLR family controls and interacts with specific CARDs.
CARD domain family control by NLR receptors included functional interaction between CARD11 and NLRP7.openaire +1 more source
NLR family gene methylation correlates with survival in breast cancer.
We studied mechanisms that specifically and significantly influence survival in human cancer by comparing DNA methylation globally in patient tumors based on total number of days (overall survival). We identified numerous instances of differential methylation of NLR family genes which was quantitatively significant indicating a family-specific propertyopenaire +1 more source
The evolution of plant NLR immune receptors and downstream signal components
Current Opinion in Plant Biology, 2023Zhu-Qing Shao +2 more
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A review of family caregiving intervention trials in oncology
Ca-A Cancer Journal for Clinicians, 2017Betty R Ferrell, Elaine Wittenberg, Fach
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