Results 251 to 260 of about 87,795 (274)
Genome-Wide Characterization of Citrus NBS-LRR Genes and Integrative Analysis of a Candidate Gene Associated with Alternaria Brown Spot-Related QTL. [PDF]
Plants (Basel)Li Y +8 more
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The NLR gene family: from discovery to present day
Nature Reviews Immunology, 2023 The mammalian NLR gene family was first reported over 20 years ago, although several genes that were later grouped into the family were already known at that time. Although it is widely known that NLRs include inflammasome receptors and/or sensors that promote the maturation of caspase 1, IL-1β, IL-18 and gasdermin D to drive inflammation and cell ...
Sushmita Jha +2 more
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Author Correction: The NLR gene family: from discovery to present day
Nature Reviews Immunology, 2023 Author Correction: The NLR gene family: from discovery to present ...
Linhoff, Michael W. +3 more
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Role of the NLR gene family members in neuroinflammation and demyelination in the CNS
, 2009 Sterile inflammation in the brain is recognized as a key component of many neurological diseases including multiple sclerosis (MS), amyotrophic lateral sclerosis, Parkinson's disease, and Alzheimer's disease. An understanding of the mechanisms by which neuroinflammation occurs and the molecular mediators involved in this process is necessary for ...
Jha, Sushmita
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Evolution of the NLR gene family in vertebrates: insights into the origin of inflammasomes. [PDF]
Nucleotide binding domain leucine rich repeat proteins (NLRs) are a family of intracellular pattern recognition receptors which play an important role in innate immune system; as well as the regulation of many other immunity-related components and signalling pathways, such as MHCs, NF-Κβ, pyroptosis, inflammasomes or MAPK (Chou et al., 2023; Hansen et ...
Pardo-Velasco, Rafael J. +3 more
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Plant Stress, 2023 Whole genome duplication plays a significant role in plant genome evolution by providing raw materials that can be modified by natural or artificial selection.
Fozia Saleem, Saad Serfraz
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Evolutionary history of the NLR gene families across lophotrochozoans
Gene, 2022NOD-like receptor (NLR) genes are critical innate immune receptors in animals and plants. Lophotrochozoans represent one of the most species-rich superphyla that includes molluscs, segmented worms, flatworms, bryozoans, and other invertebrates, which is crucial to our understanding of immune system evolution in bilaterians.
Xiaofei Zhu +3 more
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Inflammasome-Independent Roles of NLR and ALR Family Members
2023Pattern recognition receptors, including members of the NLR and ALR families, are essential for recognition of both pathogen- and host-derived danger signals. Several members of these families, including NLRP1, NLRP3, NLRC4, and AIM2, are capable of forming multiprotein complexes, called inflammasomes, that result in the activation of pro-inflammatory ...
Suman, Gupta +2 more
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