Circular RNA circ_0090231 promotes atherosclerosis in vitro by enhancing NLR family pyrin domain containing 3-mediated pyroptosis of endothelial cells. [PDF]
Ge Y +6 more
europepmc +3 more sources
The NLR gene family: from discovery to present day [PDF]
The mammalian NLR gene family was first reported over 20 years ago, although several genes that were later grouped into the family were already known at that time. Although it is widely known that NLRs include inflammasome receptors and/or sensors that promote the maturation of caspase 1, IL-1β, IL-18 and gasdermin D to drive inflammation and cell ...
Wei-Chun Chou +3 more
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Treadmill training attenuates pyroptosis in rats with cerebral ischemia/reperfusion injury [PDF]
Objective(s): Few studies have investigated the mechanism by which exercise training promotes neural repair during rehabilitation after stroke. In this study, we evaluated the neuroprotective effects of exercise training and pyroptosis-associated factors
Fang Luo +5 more
doaj +1 more source
NLR family pyrin domain containing 3 (NLRP3; NALP3; CIAS1); IL-1β [PDF]
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An NLR family member X1 mutation (p.Arg707Cys) suppresses hepatitis B virus infection in hepatocytes and favors the interaction of retinoic acid-inducible gene 1 with mitochondrial antiviral signaling protein. [PDF]
Jiao Q +8 more
europepmc +3 more sources
All in the Family: The First Whole-Genome Survey of NLR Genes [PDF]
When The Plant Cell sent an invitation for me to write about an article that had a significant impact on my research, two articles came to mind immediately. One relates to our earlier work on flowering: the 2001 article by Lilac Pnueli and colleagues ([Pnueli et al., 2001][1]), which identified ...
Detlef Weigel
openalex +4 more sources
Crystal structure of NLR family CARD domain containing 4 (NLRC4) [PDF]
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Nanopore adaptive sampling to identify the NLR-gene family in melon ( Cucumis melo L.) [PDF]
AbstractBackgroundNanopore Adaptive Sampling (NAS) offers a promising approach for assessing genetic diversity in targeted genomic regions. Herein, we design and validate an experiment to enrich a set of resistance genes in several melon cultivars as a proof of concept.ResultsWe showed that each of the 15 regions we identified in two newly assembled ...
Javier Belinchon-Moreno +13 more
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Genetic Variations of NLR family genes in Behcet's Disease. [PDF]
AbstractThis study aimed to investigate whether single nucleotide polymorphisms (SNPs) of five NLR family genes (NOD1, NOD2, NLRP1, NLRP3 and CIITA) are associated with Behcet’s disease (BD) in a Chinese Han population. The study was carried out in 950 BD patients and 1440 controls for 19 SNPs in the selected NLR genes.
Li L +6 more
europepmc +4 more sources
NLR family pyrin domain containing 6 (NLRP6; NALP6) [PDF]
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