Results 21 to 30 of about 81,787 (272)

The NLR gene family: from discovery to present day [PDF]

open access: greenNature Reviews Immunology, 2023
The mammalian NLR gene family was first reported over 20 years ago, although several genes that were later grouped into the family were already known at that time. Although it is widely known that NLRs include inflammasome receptors and/or sensors that promote the maturation of caspase 1, IL-1β, IL-18 and gasdermin D to drive inflammation and cell ...
Wei-Chun Chou   +3 more
openalex   +3 more sources

Treadmill training attenuates pyroptosis in rats with cerebral ischemia/reperfusion injury [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2022
Objective(s): Few studies have investigated the mechanism by which exercise training promotes neural repair during rehabilitation after stroke. In this study, we evaluated the neuroprotective effects of exercise training and pyroptosis-associated factors
Fang Luo   +5 more
doaj   +1 more source

All in the Family: The First Whole-Genome Survey of NLR Genes [PDF]

open access: hybridThe Plant Cell, 2019
When The Plant Cell sent an invitation for me to write about an article that had a significant impact on my research, two articles came to mind immediately. One relates to our earlier work on flowering: the 2001 article by Lilac Pnueli and colleagues ([Pnueli et al., 2001][1]), which identified ...
Detlef Weigel
openalex   +4 more sources

Nanopore adaptive sampling to identify the NLR-gene family in melon ( Cucumis melo L.) [PDF]

open access: goldBMC Genomics, 2023
AbstractBackgroundNanopore Adaptive Sampling (NAS) offers a promising approach for assessing genetic diversity in targeted genomic regions. Herein, we design and validate an experiment to enrich a set of resistance genes in several melon cultivars as a proof of concept.ResultsWe showed that each of the 15 regions we identified in two newly assembled ...
Javier Belinchon-Moreno   +13 more
openalex   +6 more sources

Genetic Variations of NLR family genes in Behcet's Disease. [PDF]

open access: yesSci Rep, 2016
AbstractThis study aimed to investigate whether single nucleotide polymorphisms (SNPs) of five NLR family genes (NOD1, NOD2, NLRP1, NLRP3 and CIITA) are associated with Behcet’s disease (BD) in a Chinese Han population. The study was carried out in 950 BD patients and 1440 controls for 19 SNPs in the selected NLR genes.
Li L   +6 more
europepmc   +4 more sources

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