Results 161 to 170 of about 122,087 (266)

Cytosolic activation of cell death and stem rust resistance by cereal MLA-family CC-NLR proteins. [PDF]

Proc Natl Acad Sci U S A, 2016
Cesari S, Moore J, Chen C, Webb D, Periyannan S, Mago R, Bernoux M, Lagudah ES, Dodds PN.   +8 more
europepmc   +1 more source

Decoding MAPK cascades in plant immunity: Activation, regulation, integration, and pathogen manipulation

Journal of Integrative Plant Biology, EarlyView.
This review focuses on mitogen‐activated protein kinase (MAPK) activation and summarizes how plants regulate and integrate MAPK signaling in modulating plant immune responses. It also examines the effectors pathogens have evolved to manipulate MAPK activation and thereby inhibit plant immunity.
Guitao Zhong, Zhanchun Wang, Dingzhong Tang, Wei Wang   +3 more
wiley   +1 more source

Genomic organization, domain assortments, and nucleotide-binding domain diversity of NLR proteins in Sordariales fungi. [PDF]

PLoS Genet
Bonometti L, Charriat F, Hensen N, Miñana-Posada S, Johannesson H, Gladieux P.   +5 more
europepmc   +1 more source

Activated CCG10‐NLR: Octameric resistosome driving sustained calcium influx

Journal of Integrative Plant Biology, EarlyView.
This commentary spotlights landmark work from Guo et al. resolving the structure of the octameric resistosome formed by the active CCG10‐nucleotide‐binding leucine‐rich repeat (NLR) immune receptor WAI3, which triggers sustained, multi‐phasic Ca2+ influx.
Huayue Sun, Xiaohuan Jin, Mengchen Hu, Daowen Wang, Zheng Qing Fu   +4 more
wiley   +1 more source

The Biophysical Characterisation and SAXS Analysis of Human NLRP1 Uncover a New Level of Complexity of NLR Proteins. [PDF]

PLoS One, 2016
Martino L, Holland L, Christodoulou E, Kunzelmann S, Esposito D, Rittinger K.   +5 more
europepmc   +1 more source

Epithelial‐Mesenchymal Transition, Immune Response, and Extracellular Matrix Remodelling in Oral Cancer

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Aim This retrospective study investigates the interplay between epithelial‐mesenchymal transition (EMT) and immune response within the tumor microenvironment (TME) of oral squamous cell carcinoma (OSCC). Methodology Immunohistochemistry was conducted on OSCC specimens to evaluate the expression of podoplanin (PDP), E‐cadherin (CDH1), vimentin (
Nicole Lonni, Camilla Kammer Pereira, Amanda Maciel Costa, Aline Hsiao Bona, Andressa Fernanda Paza Miguel, Elis Ângela Batistella, Daniella Serafin Couto Vieira, Elena Riet Correa Rivero   +7 more
wiley   +1 more source

Activation of a plant NLR complex through heteromeric association with an autoimmune risk variant of another NLR

, 2017
When independently evolved immune receptor variants meet in hybrid plants, they can activate immune signaling even in the absence of non-self recognition. Such autoimmune risk alleles have recurrently evolved at a complex NLR locus in A.
Weigel, D. ; https://orcid.org/, Chae, E. ; https://orcid.org/, Chung, E., Dangl, J., Tran, D. ; https://orcid.org/, Zhou, J., Schwab, R. ; https://orcid.org/   +6 more
core  

The battle within: How pathogen effectors suppress NLR-mediated immunity.

To successfully colonise plants, pathogens must circumvent the plant immune system. Intracellular immune receptors of the nucleotide-binding leucine-rich repeat (NLR) class of proteins are major components of the plant immune system.

core   +1 more source

Early‐Onset Oral Squamous Cell Carcinoma: Emerging Biological Insights, Risk Factors and Clinical Implications

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background Early‐onset oral squamous cell carcinoma (EO‐OSCC), commonly defined as occurring in individuals under 50 years of age, is increasingly recognized as a potentially distinct clinical subset with differences in exposure patterns and tumor biology compared with conventional oral squamous cell carcinoma (OSCC).
Gennaro Musella, Cristina D'Antonio, Federica Canfora, Michele D. Mignogna, Valentino Vellone, Vito Carlo Alberto Caponio, Amerigo Giudice, Alessandro Villa, Daniela Adamo   +8 more
wiley   +1 more source

The soybean plasma membrane GmDR1 protein conferring broad-spectrum disease and pest resistance regulates several receptor kinases and NLR proteins. [PDF]

Sci Rep
Ngaki MN, Srivastava SK, Feifei W, Bhattacharyya MK.   +3 more
europepmc   +1 more source