Results 11 to 20 of about 122,087 (266)
Resurrection of plant disease resistance proteins via helper NLR bioengineering [PDF]
Science Advances, 2022 Abstract Parasites counteract host immunity by suppressing helper NLR proteins that function as central nodes in immune receptor networks. Understanding the mechanisms of immunosuppression can lead to strategies for bioengineering disease resistance.
Mauricio P. Contreras +14 more
core +7 more sources
A new eye on NLR proteins: focused on clarity or diffused by complexity? [PDF]
Current Opinion in Immunology, 2012 The nucleotide-binding domain leucine-rich repeat proteins (NLRs) represent the major class of intracellular innate immune receptors in plants and animals. Understanding their functions is a major challenge in immunology.
Marc T Nishimura, Jeffery L Dangl
exaly +4 more sources
Editorial: NLR-Protein Functions in Immunity [PDF]
Frontiers in Immunology, 2015 Since Janeway (1) and Matzinger (2) put forward two distinct concepts of innate immune recognition, arguing that the driving force that initiates immune reponses is the recognition of microbial patterns or endogenous danger signals, respectively, we have acquired a tremendous wealth of knowledge of the protein families involved.
Fritz, Jörg H., Kufer, Thomas A.
openaire +3 more sources
Recent advances in plant NLR structure, function, localization and signaling
Frontiers in Immunology, 2013 Nucleotide-binding domain leucine-rich repeat (NLR) proteins play a central role in the innate immune systems of plants and vertebrates. In plants, NLR proteins function as intracellular receptors that detect pathogen effector proteins directly, or ...
Dong eQi, Roger W Innes
doaj +2 more sources
Current Opinion in Plant Biology, 2021 Recent progress in large-scale sequencing, genomics, and rapid gene isolation techniques has accelerated the identification of race-specific resistance (R) genes and their corresponding avirulence (Avr) genes in wheat, barley, rye, and their wild relatives.
Javier Sánchez-Martín, Beat Keller
exaly +3 more sources
Assessing ATP binding and hydrolysis by NLR proteins. [PDF]
Methods Mol Biol, 2013 Nucleotide-binding and leucine rich repeat domain-containing proteins (NLRs) are central to the formation of many inflammasome complexes. Several inflammasome forming NLR proteins are known to be ATPases, but the nucleotide binding specificity of many remains to be characterized. The oligomerization of NLR proteins and assembly of inflammasomes require
Mo J, Duncan JA.
europepmc +4 more sources
The Landscape of Integrated Domains of Angiosperm NLR Genes Reveals Continuous Architecture Evolution of Plant Intracellular Immune Receptors [PDF]
PlantsNucleotide-binding site-leucine-rich repeat (NLR) proteins are key intracellular immune receptors in plants. Integrated domains (IDs) can occasionally be fused with NLRs, contributing to their functional diversity. However, the diversity and evolutionary
Zhen Zeng +5 more
doaj +2 more sources
A novel conserved mechanism for plant NLR protein pairs: the ‘integrated decoy’ hypothesis [PDF]
Frontiers in Plant Science, 2014 Plant immunity is often triggered by the specific recognition of pathogen effectors by intracellular nucleotide-binding, leucine-rich repeat (NLR) receptors.
Stella ecesari +5 more
doaj +6 more sources
Plant TRAF Proteins Regulate NLR Immune Receptor Turnover [PDF]
Cell Host and Microbe, 2016 In animals, Tumor necrosis factor receptor-associated factor (TRAF) proteins are molecular adaptors that regulate innate and adaptive immunity, development, and abiotic stress responses. Although gene families encoding TRAF domain-containing proteins exhibit enriched diversity in higher plants, their biological roles are poorly defined. Here, we report
Shuai Huang, Kevin Ao
exaly +4 more sources
Lessons in Effector and NLR Biology of Plant-Microbe Systems
Molecular Plant-Microbe Interactions, 2018 A diversity of plant-associated organisms secrete effectors—proteins and metabolites that modulate plant physiology to favor host infection and colonization.
Aleksandra Białas +18 more
doaj +3 more sources