Results 31 to 40 of about 122,087 (266)

NLR-protein functions in immunity

open access: yesFrontiers in Immunology, 2015
The Nod-like receptor (NLR) family of proteins are evolutionary conserved molecules that in plants and mammals have been implicated in innate immune sensing of microbes and infection-associated physiological changes, contributing to immune protection of the challenged host organism through the instruction of inflammatory responses, antimicrobial ...
Kufer, Thomas A., Fritz, Jörg H.
openaire   +5 more sources

Regulation of intestinal microbiota by the NLR protein family [PDF]

open access: yesInternational Immunology, 2013
Abstract The human intestine harbors a diverse microbial community consisting of a large number of bacteria and other micro-organisms that have co-evolved with the host intestinal immune system. During this process, microbiota and the host immune system shape one another by various mechanisms to achieve a successful symbiotic ...
Amlan, Biswas, Koichi S, Kobayashi
openaire   +2 more sources

NLR receptor networks in plants [PDF]

open access: yes, 2022
To fight off diverse pathogens and pests, the plant immune system must recognize these invaders; however, as plant immune receptors evolve to recognize a pathogen, the pathogen often evolves to escape this recognition. Plant–pathogen co-evolution has led
Kamoun, Sophien, Adachi, Hiroaki
core   +1 more source

Regulation of NLR stability in plant immunity [PDF]

open access: yesFrontiers of Agricultural Science and Engineering, 2019
Plant nucleotide binding domain and leucine-rich repeat (NLR) receptors recognize pathogen effectors directly or indirectly and mediate innate immune responses.
Tao WANG, Jiaxin LI, Qian-Hua SHEN
doaj   +1 more source

Activation and regulation of NLR immune receptor networks [PDF]

open access: yes, 2022
Plants have many types of immune receptors that recognize diverse pathogen molecules and activate the innate immune system. The intracellular immune receptor family of nucleotide-binding domain leucine-rich repeat-containing proteins (NLRs) perceives ...
Kourelis, Jiorgos   +3 more
core   +1 more source

Genomic evidence for genes encoding leucine-rich repeat receptors linked to resistance against the eukaryotic extra- and intracellular Brassica napus pathogens Leptosphaeria maculans and Plasmodiophora brassicae. [PDF]

open access: yesPLoS ONE, 2018
Genes coding for nucleotide-binding leucine-rich repeat (LRR) receptors (NLRs) control resistance against intracellular (cell-penetrating) pathogens.
Henrik U Stotz   +7 more
doaj   +1 more source

Molecular and functional analyses of a maize autoactive NB-LRR protein identify precise structural requirements for activity.

open access: yesPLoS Pathogens, 2015
Plant disease resistance is often mediated by nucleotide binding-leucine rich repeat (NLR) proteins which remain auto-inhibited until recognition of specific pathogen-derived molecules causes their activation, triggering a rapid, localized cell death ...
Guan-Feng Wang   +5 more
doaj   +1 more source

New recognition specificity in a plant immune receptor by molecular engineering of its integrated domain

open access: yesNature Communications, 2022
Plant NLR proteins trigger immune responses upon recognition of pathogen effectors. Here the authors show that the integrated decoy domain of the rice NLR RGA5 can be engineered to trigger immune responses upon binding a non-cognate effector.
Stella Cesari   +10 more
doaj   +1 more source

Construction and Identification of an NLR-Associated Prognostic Signature Revealing the Heterogeneous Immune Response in Skin Cutaneous Melanoma

open access: yesClinical, Cosmetic and Investigational Dermatology, 2023
Yi Geng,1 Yu-Jie Sun,1 Hao Song,1 Qiu-Ju Miao,1 Yi-Fei Wang,1 Jin-Liang Qi,2 Xiu-Lian Xu,1 Jian-Fang Sun1 1Institute of Dermatology, Peking Union Medical College and Chinese Academy of Medical Sciences, Nanjing, 210042, People’s Republic of China; 2State
Geng Y   +7 more
doaj  

Pathogen effector recognition-dependent association of NRG1 with EDS1 and SAG101 in TNL receptor immunity

open access: yesNature Communications, 2021
For defence, plants deploy nucleotide binding, leucine-rich repeat (NLR) immune receptors to detect pathogens that signal via modular networks of downstream proteins.
Xinhua Sun   +15 more
doaj   +1 more source

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