Results 31 to 40 of about 134,694 (275)

Regulation of NLR stability in plant immunity [PDF]

Frontiers of Agricultural Science and Engineering, 2019
Plant nucleotide binding domain and leucine-rich repeat (NLR) receptors recognize pathogen effectors directly or indirectly and mediate innate immune responses.
Tao WANG, Jiaxin LI, Qian-Hua SHEN
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Systemic inflammation, nutritional status and survival in patients with cancer [PDF]

, 2009
Systemic inflammation, nutritional status and survival in patients with ...
Al Murri, Brown, Cho, Crumley, Crumley, Crumley, Fearon, Forrest, Forrest, Gabay, Glen, Gomez, Gridelli, Halazun, Hara, Hilmy, Ishizuka, Jamieson, Karakiewicz, Kerem, Kobayashi, Krzystek-Korpacka, Leitch, Malik, Marsik, McMillan, McMillan, Morley, Ramsey, Read, Sharma, Sharma, Walsh, Yamanaka   +33 more
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Resurrection of plant disease resistance proteins via helper NLR bioengineering

Science Advances, 2022
AbstractParasites counteract host immunity by suppressing helper NLR proteins that function as central nodes in immune receptor networks. Understanding the mechanisms of immunosuppression can lead to strategies for bioengineering disease resistance. Here, we show that a cyst nematode virulence effector binds and inhibits oligomerization of the helper ...
Mauricio P. Contreras, Hsuan Pai, Muniyandi Selvaraj, AmirAli Toghani, David M. Lawson, Yasin Tumtas, Cian Duggan, Enoch Lok Him Yuen, Clare E. M. Stevenson, Adeline Harant, Abbas Maqbool, Chih-Hang Wu, Tolga O. Bozkurt, Sophien Kamoun, Lida Derevnina   +14 more
openaire   +5 more sources

Molecular and functional analyses of a maize autoactive NB-LRR protein identify precise structural requirements for activity.

PLoS Pathogens, 2015
Plant disease resistance is often mediated by nucleotide binding-leucine rich repeat (NLR) proteins which remain auto-inhibited until recognition of specific pathogen-derived molecules causes their activation, triggering a rapid, localized cell death ...
Guan-Feng Wang, Jiabing Ji, Farid El-Kasmi, Jeffery L Dangl, Guri Johal, Peter J Balint-Kurti   +5 more
doaj   +1 more source

New recognition specificity in a plant immune receptor by molecular engineering of its integrated domain

Nature Communications, 2022
Plant NLR proteins trigger immune responses upon recognition of pathogen effectors. Here the authors show that the integrated decoy domain of the rice NLR RGA5 can be engineered to trigger immune responses upon binding a non-cognate effector.
Stella Cesari, Yuxuan Xi, Nathalie Declerck, Véronique Chalvon, Léa Mammri, Martine Pugnière, Corinne Henriquet, Karine de Guillen, Vincent Chochois, André Padilla, Thomas Kroj   +10 more
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Construction and Identification of an NLR-Associated Prognostic Signature Revealing the Heterogeneous Immune Response in Skin Cutaneous Melanoma

Clinical, Cosmetic and Investigational Dermatology, 2023
Yi Geng,1 Yu-Jie Sun,1 Hao Song,1 Qiu-Ju Miao,1 Yi-Fei Wang,1 Jin-Liang Qi,2 Xiu-Lian Xu,1 Jian-Fang Sun1 1Institute of Dermatology, Peking Union Medical College and Chinese Academy of Medical Sciences, Nanjing, 210042, People’s Republic of China; 2State
Geng Y, Sun YJ, Song H, Miao QJ, Wang YF, Qi JL, Xu XL, Sun JF   +7 more
doaj  

Pathogen effector recognition-dependent association of NRG1 with EDS1 and SAG101 in TNL receptor immunity

Nature Communications, 2021
For defence, plants deploy nucleotide binding, leucine-rich repeat (NLR) immune receptors to detect pathogens that signal via modular networks of downstream proteins.
Xinhua Sun, Dmitry Lapin, Joanna M. Feehan, Sara C. Stolze, Katharina Kramer, Joram A. Dongus, Jakub Rzemieniewski, Servane Blanvillain-Baufumé, Anne Harzen, Jaqueline Bautor, Paul Derbyshire, Frank L. H. Menke, Iris Finkemeier, Hirofumi Nakagami, Jonathan D. G. Jones, Jane E. Parker   +15 more
doaj   +1 more source

Modulation of plant autophagy during pathogen attack [PDF]

, 2017
In plants, the highly conserved catabolic process of autophagy has long been known as a means of maintaining cellular homeostasis and coping with abiotic stress conditions. Accumulating evidence has linked autophagy to immunity against invading pathogens,
Bozkurt, Tolga O., Duggan, Cian, Leary, Alexandre Y, Pandey, Pooja, Salguero Linares, Jose, Sanguankiattichai, Nattapong, Savage, Zachary D, Segretin, Maria Eugenia, Tumtas, Yasin, Yow, Rui Jin   +9 more
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Staging the tumor and staging the host: A two centre, two country comparison of systemic inflammatory responses of patients undergoing resection of primary operable colorectal cancer [PDF]

, 2017
Background: How systemic inflammation-based prognostic scores such as the modified Glasgow Prognostic Score (mGPS) and neutrophil:lymphocyte ratio (NLR) differ across populations of patients with colorectal cancer (CRC) remains unknown.
Aoki, Taku, Horgan, Paul G., Ishizuka, Mitsuru, Iwasaki, Yoshimi, Kubota, Keiichi, McMillan, Donald C., McSorley, Stephen T., Nagata, Hitoshi, Park, James H., Roxburgh, Campbell S.D., Takagi, Kazutoshi   +10 more
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Evaluation of slaughter stress responses in the dromedary camel [PDF]

, 2019
Slaughter stress responses were evaluated in the dromedary camel by analyzing hematocrit (Hct), neutrophil/lymphocyte ratio (NLR), hemolysis (H%), catalase activity (CATa) and plasma levels of cortisol (COR), triiodothyronine (T3), thyroxine (T4 ...
Abbadi, Najia, El Khasmi, Mohammed, Faye, Bernard, Lemrhamed, Abdelilah, Tabite, Rabab   +4 more
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