Results 51 to 60 of about 98,851 (337)

Estradiol and testosterone levels in patients undergoing partial hepatectomy - A possible signal for hepatic regeneration? [PDF]

open access: yes, 1989
In five adult male patients undergoing a 40-60% partial hepatectomy, serum sex hormone levels before and after hepatic resection were determined. Blood was drawn immediately prior to each surgical procedure and at specified time points postoperatively ...
A Francavilla   +34 more
core   +2 more sources

NLR receptors in plant immunity: making sense of the alphabet soup

open access: yesEMBO reports, 2023
AbstractPlants coordinately use cell‐surface and intracellular immune receptors to perceive pathogens and mount an immune response. Intracellular events of pathogen recognition are largely mediated by immune receptors of the nucleotide binding and leucine rich‐repeat (NLR) classes.
Contreras, Mauricio P.   +4 more
openaire   +4 more sources

The allelic rice immune receptor Pikh confers extended resistance to strains of the blast fungus through a single polymorphism in the effector binding interface.

open access: yesPLoS Pathogens, 2021
Arms race co-evolution drives rapid adaptive changes in pathogens and in the immune systems of their hosts. Plant intracellular NLR immune receptors detect effectors delivered by pathogens to promote susceptibility, activating an immune response that ...
Juan Carlos De la Concepcion   +5 more
doaj   +1 more source

Cabazitaxel in the treatment of metastatic castration-resistant prostate cancer: patient selection and special considerations. [PDF]

open access: yes, 2017
Cabazitaxel is an effective chemotherapeutic agent used in the treatment of metastatic castration-resistant prostate cancer (mCRPC) refractory to docetaxel.
Hoffman-Censits, Jean, Patel, Sheel
core   +3 more sources

Effects of Primary Tumor Resection on Metastatic Breast Cancer Survival and the Predictive Power of Neutrophil: Lymphocyte Ratio on Prognosis

open access: yesEuropean Journal of Breast Health, 2021
Objective:The aim was to investigate the effect of primary tumor resection (PTR) on survival in metastatic breast cancer patients and to assess the power of the neutrophil-to-lymphocyte ratio (NLR) regarding the prediction of prognosis in this patient ...
Yaşar Çöpelci   +4 more
doaj   +1 more source

NLRP2 controls age-associated maternal fertility [PDF]

open access: yes, 2016
Nucleotide-binding domain and leucine-rich repeat (NLR) proteins are well-known for their key roles in the immune system. Ectopically expressed NLRP2 in immortalized cell lines assembles an inflammasome and inhibits activation of the proinflammatory ...
Agostini   +24 more
core   +2 more sources

Uncovering the repertoire of legume NLR immune receptors

open access: yes, 2022
The legume family (Fabaceae) is the third-largest angiosperm family and is considered one of the most important crop families. Biotic stress constrains legume yield, and resistance breeding is currently considered the most sustainable management method to deal with pathogen pressure in the field.
Marques, Rita Maravilha   +4 more
openaire   +1 more source

Physiological and pathophysiological functions of NLRP6: pro- and anti-inflammatory roles

open access: yesCommunications Biology, 2022
This review discusses emerging roles for the NLR family pyrin domain containing 6 receptor (NLRP6) in intestinal homeostasis, inflammation, cancer, the nervous system and liver disease.
Diego Angosto-Bazarra   +2 more
doaj   +1 more source

Protein-protein interactions in the RPS4/RRS1 immune receptor complex.

open access: yesPLoS Pathogens, 2017
Plant NLR (Nucleotide-binding domain and Leucine-rich Repeat) immune receptor proteins are encoded by Resistance (R) genes and confer specific resistance to pathogen races that carry the corresponding recognized effectors.
Sung Un Huh   +7 more
doaj   +1 more source

An EDS1 heterodimer signalling surface enforces timely reprogramming of immunity genes in Arabidopsis

open access: yesNature Communications, 2019
CC and TIR-domain type NLR receptors trigger plant immunity in response to pathogen effectors. Here, Bhandari et al. show that the EP-domain surface of EDS1 heterodimers signals downstream of both receptor types and ensures a rapid transcriptional ...
Deepak D. Bhandari   +6 more
doaj   +1 more source

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