Results 191 to 200 of about 131,202 (338)

The NLRP3 Inflammasome Mediates In Vivo Innate Immunity to Influenza A Virus through Recognition of Viral RNA

, 2009
Irving C. Allen, Margaret A. Scull, Chris Moore, Eda K. Holl, Erin McElvania, Debra J. Taxman, Elizabeth H. Guthrie, Raymond J. Pickles, Jenny P.‐Y. Ting   +8 more
openalex   +2 more sources

Role of IL-1 and the Nlrp3/caspase-1/IL-1 axis in cigarette smoke-induced pulmonary inflammation and COPD [PDF]

, 2011
N. Pauwels, Ken R. Bracke, Lieven Dupont, Geert R. Van Pottelberge, Sharen Provoost, Tom Vanden Berghe, Peter Vandenabeele, Bart N. Lambrecht, Guy Joos, Guy Brusselle   +9 more
openalex   +1 more source

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

Mycobacterium abscessus activates the NLRP3 inflammasome via Dectin‐1–Syk and p62/SQSTM1 [PDF]

, 2011
Hye‐Mi Lee, Jae‐Min Yuk, Ki‐Hye Kim, Jichan Jang, Gun Kang, Jin Bong Park, Ji Woong Son, Eun‐Kyeong Jo   +7 more
openalex   +1 more source

Lithocarpus polystachyus Rehd. leaves aqueous extract inhibits learning and memory impairment in Alzheimer's disease rats: Involvement of the SIRT6/NLRP3 signaling pathway

Ibrain, EarlyView.
The findings of this study demonstrate that STAE effectively counteracts the learning and memory impairment induced by Aβ25‐35 in rats. This effect is attributed, at least in part, to the regulation of the SIRT6/NLRP3 signaling pathway, which inhibits neuroinflammation and oxidative stress.
Wendan Wu, You Yan, Tingting Yi, Yu Wei, Jianmei Gao, Qihai Gong   +5 more
wiley   +1 more source

Houttuynia cordata-Derived Exosome-Like Nanoparticles Mitigate Colitis in Mice via Inhibition of the NLRP3 Signaling Pathway and Modulation of the Gut Microbiota

International Journal of Nanomedicine
Jian-Hong Li,1,2,* Jing Xu,1,2,* Chen Huang,1,2 Jin-Xia Hu,1,2 Hao-Ming Xu,1,2 Xue Guo,1,2 Yan Zhang,1,2 Jing-Kui Xu,1,2 Yao Peng,3 Yong Zhang,1,2 Min-Zheng Zhu,1,2 You-Lian Zhou,1,2 Yu-Qiang Nie1,2 1Department of Gastroenterology and Hepatology,
Li JH, Xu J, Huang C, Hu JX, Xu HM, Guo X, Zhang Y, Xu JK, Peng Y, Zhang Y, Zhu MZ, Zhou YL, Nie YQ   +12 more
doaj  

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

, 2010
Peter Duewell, Hajime Kono, Katey J. Rayner, Cherilyn M. Sirois, Gregory I. Vladimer, Franz Bauernfeind, George S. Abela, Luigi Franchi, Guillermo G. Nuñez, Max Schnurr, Terje Espevik, Egil Lien, Katherine A. Fitzgerald, Kenneth L. Rock, Kathryn J. Moore, Samuel D. Wright, Veit Hornung, Eicke Latz   +17 more
openalex   +2 more sources

Role of TREM1 in the sevoflurane‐induced inflammatory activation of microglia in vitro

Ibrain, EarlyView.
Perioperative neurocognitive disorders (PNDs) are one of the most common complications in perioperative patients, and neuroinflammatory reaction mediated by microglia plays a key role in their formation. Triggering receptor expressed on myeloid cells 1 (TREM1) is a key regulator of inflammation.
Chunchun Tang, Yuhang Zhu, Dexing Liu, Xue Zheng, Junli Jiang, Wanqiu Yu, Yinan Zhang, Dongqin Chen, Zhaoqiong Zhu   +8 more
wiley   +1 more source

Hemorrhagic Shock Activation of NLRP3 Inflammasome in Lung Endothelial Cells [PDF]

, 2011
Meng Xiang, Xiao‐Lian Shi, Yuehua Li, Jia Xu, Lianhua Yin, Guozhi Xiao, Melanie J. Scott, Timothy R. Billiar, Mark A. Wilson, Jie Fan   +9 more
openalex   +1 more source

Immunomodulatory natural polysaccharide‐based nanoparticles for the treatment of neurodegenerative diseases

Ibrain, EarlyView.
Polysaccharide‐based nanoparticles offer versatile platforms for drug delivery and immune modulation in neurodegenerative diseases. This review highlights their potential in treating Alzheimer's, Parkinson's, and multiple sclerosis, focusing on targeted delivery and neuroinflammation.
Leto‐Aikaterini Tziveleka, Mariafrancesca Cascione, Paolo Pellegrino, Annalisa Bianco, Stefano Leporatti, Valeria De Matteis   +5 more
wiley   +1 more source