Results 241 to 250 of about 150,409 (337)

Recombinant Thrombomodulin Domain 1 Promotes Diabetic Corneal Wound Healing by Inhibiting HMGB1 Production and NLRP3 Inflammasome. [PDF]

Mediators Inflamm
Chen KY, Peng IC, Wu HL, Kuo CH, Huang YH.   +4 more
europepmc   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Pyroptosis in cardiovascular diseases: molecular mechanisms, pathological roles, and therapeutic implications. [PDF]

Am J Cardiovasc Dis
Liu XS, Li ZY, Wang ST, Qiao Q, Ye XR, Cheng L, Hu Y, Zhu L, Yang JL, Zhang HL, Zhang JJ.   +10 more
europepmc   +1 more source

The effects of sodium–glucose cotransporter 2 inhibitors on the ‘forgotten’ right ventricle

ESC Heart Failure, Volume 12, Issue 2, Page 1045-1058, April 2025.
Abstract With the progress in diagnosis, treatment and imaging techniques, there is a growing recognition that impaired right ventricular (RV) function profoundly affects the prognosis of patients with heart failure (HF), irrespective of their left ventricular ejection fraction (LVEF).
Liangzhen Qu, Xueting Duan, Han Chen
wiley   +1 more source

Pyroptosis in Peripheral Neuropathy: From Molecular Mechanisms to Therapeutic Targeting. [PDF]

CNS Neurosci Ther
Wei J, Liuyuan M, Ye Z, Wang X, Zhou X, Shan Y, He C, Zhu C, Zhou C, Bao J, Zhang Y, Chen G.   +11 more
europepmc   +1 more source

Targeting the Nrf2/TGF‐β1/Smad Signaling Pathway: A Novel Strategy for Urolithin A to Alleviate Renal Fibrosis

Food Frontiers, EarlyView.
The diagram of the mechanism of action by which UroA regulates RF. ABSTRACT The global prevalence and mortality rates associated with chronic kidney disease (CKD) have been on a continuous rise over recent decades. Renal fibrosis (RF) serves as a critical factor in the progression of CKD to end‐stage renal disease.
Xue Wu, Jiating Li, Yonghui Dong, Jia Li, Ji Bian, Chao Liu, Hongbo Zhang, Lin Han, Min Wang   +8 more
wiley   +1 more source

Inflammasomes as the molecular hub of cardiovascular-metabolic-immune comorbidity networks. [PDF]

Front Immunol
Qian X, Sun J, Li F, Xu L, Hu X, Dong N, Li G.   +6 more
europepmc   +1 more source

Efficacy of novel selective NLRP3 inhibitors in human and murine retinal pigment epithelial cells

, 2019
Luping Wang, Sarah Schmidt, Petra P. Larsen, Johanna Meyer, William Roush, Eicke Latz, Frank G. Holz, Tim U. Krohne   +7 more
openalex   +1 more source

血清NLRP3與IL-1β聯合檢測在SLE早期診斷中的臨床應用分析

林 朔
openalex   +2 more sources

Differential Peripheral NLRP3 Inflammasome Expression in Parkinson's Disease and Multiple System Atrophy [PDF]

Jeffrey Lee, Han‐Joon Kim, Hữu Đạt Nguyễn, Suk Jun Song, T. Nguyen Thanh, In Hee Kwak, HK Choi, Hyeo‐Il Ma, Young‐Eun Kim   +8 more
openalex   +1 more source