Results 251 to 260 of about 113,850 (298)

<i>Polygonati Odorati Rhizoma</i> Extract Ameliorates Obesity and Insulin Resistance Potentially Through Modulation of the TLR4/NLRP3 Signaling Pathway. [PDF]

Diabetes Metab Syndr Obes
Deng X, Wu Y, Chen X, Zeng J, Li W, Wang X, Luo H, Luo Y.   +7 more
europepmc   +1 more source

Thiolutin alleviates acute graft-versus-host disease (aGVHD) in a mouse model of allogeneic hematopoietic stem cell transplantation. [PDF]

Blood Sci
Li X, Zhao K, Gao R, Lv ZC, Wang Q, Ren GM, Gao HY, Xiang SS, Zhu YX, Wu YQ, Sun HY, Chen H, Yin RH, Yang XM, Li CY, Ning HM.   +15 more
europepmc   +1 more source

NETosis in the Kidney, Liver, and Lung of Mice With Cecal Ligation and Puncture-Induced Sepsis and the Ameliorating Effects of Adipose-Derived Stem Cell Exosomes. [PDF]

Kaohsiung J Med Sci
Wu SC, Lu TH, Wu YC, Lin CW, Tsai CW, Hsieh CH.   +5 more
europepmc   +1 more source

Targeting Ferroptosis, Pyroptosis, and NRF2 Signaling with Dietary Polyphenols in Diabetic Microvascular Complications: An Integrative Review. [PDF]

Nutrients
García-Muñoz AM, Victoria-Montesinos D, Morillas-Ruiz JM.   +2 more
europepmc   +1 more source

EXPRESSION OF CONCERN: KLF4 Interacts With TXNIP to Modulate the Pyroptosis in Ulcerative Colitis via Regulating NLRP3 Signaling. [PDF]

Immun Inflamm Dis
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Vasculitis and the NLRP3 inflammasome

Current Opinion in Rheumatology, 2023
Purpose of review Vasculitis are a group of heterogeneous conditions characterized by chronic inflammation of blood vessels, leading to tissue destruction and organ failure. Vasculitis is an inflammatory process in which immune effector cells infiltrate blood vessels and surrounding tissues.
Kamel, Hamzaoui, Agnès, Hamzaoui
openaire   +2 more sources

NLRP3 inflammasome inhibitor INF39 attenuated NLRP3 assembly in macrophages

International Immunopharmacology, 2021
INF39 is a nontoxic, irreversible, acrylate-based NLRP3 inhibitor and a further optimization of ethyl 2-((2-chlorophenyl) hydroxyl) methyl) acrylate (INF4E). However, the detail mechanism and the direct target of its anti-inflammatory activity is not clear. Here, we show that INF39 is a specific inhibitor for NLRP3 inflammasome activation.
Yuhua Shi, Qian Lv, Mengjie Zheng, Hongxiang Sun, Fushan Shi   +4 more
openaire   +2 more sources

Assessment of NLRP3 Inflammasome Activation and NLRP3-NEK7 Complex Assembly

2023
The NLRP3 inflammasome is a critical component of innate immunity that activates caspase-1 to induce inflammation in response to a wide spectrum of endogenous and exogenous stimuli. NLRP3 inflammasome activation has been shown by assays for the cleavage of caspase-1 and gasdermin D, the maturation of IL-1β and IL-18, and ASC speck formation in innate ...
Nathan, Kelley, Yuan, He
openaire   +2 more sources

LMP7 inhibits the activation of NLRP3 inflammasome through interaction with NLRP3

Biochemical and Biophysical Research Communications, 2020
The innate immune system recognizes pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs) by coding pattern recognition receptors (PRRs). As a well-known inflammasome, NLRP3 plays an essential role in helping the host immune response and driving antiviral processes.
Jing Jin, Wenbiao Wang, Aixin Li, Jianguo Wu   +3 more
openaire   +2 more sources

NLRP12 interacts with NLRP3 to block the activation of the human NLRP3 inflammasome

Science Signaling
Inflammasomes are multiprotein complexes that drive inflammation and contribute to protective immunity against pathogens and immune pathology in autoinflammatory diseases. Inflammasomes assemble when an inflammasome scaffold protein senses an activating signal and forms a signaling platform with the inflammasome adaptor protein ASC.
Coombs, Jared, Zamoshnikova, Alina, Holley, Caroline, Maddugoda, Madhavi, Teo, Daniel Eng Thiam, Chauvin, Camille, Poulin, Lionel Franz, Vitak, Nazarii, Ross, Connie, Mellacheruvu, Manasa, Coll, Rebecca, Heinz, Leonhard, Burgener, Sabrina, Emming, Stefan, Chamaillard, Mathias, Boucher, Dave, Schroder, Kate   +16 more
openaire   +4 more sources