Results 261 to 270 of about 113,850 (298)

Arteannuin B, a novel NLRP3 inhibitor, suppresses NLRP3 inflammasome in macrophages and alleviates NLRP3-related diseases

International Immunopharmacology
The NLRP3 inflammasome plays pivotal roles in inflammatory pathogenesis, yet developing specific inhibitors remains challenging due to toxicity risks and incomplete mechanistic targeting. FDA has authorized no NLRP3 inhibitor for therapeutic application in clinical use.
Weifeng, Li, Zhiyu, Liang, Mingxiang, Jiang, Jingjing, Shao, Zhihui, Wei, Jinfeng, Sun, Haowen, Xu, Qiluo, Ni, Xinting, Lv, Guang, Liang, Xiangwei, Xu   +10 more
openaire   +2 more sources

The NLRP3 Conundrum

Arthritis & Rheumatology, 2023
James T. Rosenbaum, Tejpal Gill, Tammy M. Martin   +2 more
openaire   +2 more sources

NLRP3 modulators

2021
ZHANG YONG, GAVAI ASHVINIKUMAR V
  +11 more sources

NLRP3 modulators

2022
WATTERSON SCOTT HUNTER, O'MALLEY DANIEL, GAVAI ASHVINIKUMAR V, GONG HUA, TARBY CHRISTINE M   +4 more
openaire   +4 more sources

NLRP3 cages revealed by full-length mouse NLRP3 structure control pathway activation

Cell, 2021
Chen Shen, Hao Wu, Shaun Rawson
exaly  

ZDHHC5-mediated NLRP3 palmitoylation promotes NLRP3-NEK7 interaction and inflammasome activation

Molecular Cell, 2023
Pingfeng Zhang, Huadong Pei
exaly  

NLRP3 modulators

2020
GLICK GARY D, GHOSH SHOMIR, ROUSH WILLIAM R, OLHAVA EDWARD JAMES, O'MALLEY DANIEL   +4 more
openaire   +8 more sources

NLRP3 inflammasome activation and cell death

Cellular and Molecular Immunology, 2021
Rongbin Zhou, Yi Huang
exaly  

NLRP3 and pyroptosis blockers for treating inflammatory diseases

Trends in Pharmacological Sciences, 2022
Kate Schröder, Rebecca Coll, Pelegrín P   +2 more
exaly  

IKKβ primes inflammasome formation by recruiting NLRP3 to the trans-Golgi network

Immunity, 2022
Veit Hornung, Dhruv Chauhan, Tatsuya Kozaki   +2 more
exaly