Results 271 to 280 of about 115,042 (335)

TAFA4 Mitigates Intervertebral Disc Degeneration by Modulating Macrophage Polarization and Inhibiting ROS-NLRP3 Inflammasome Activation [PDF]

Yu Ding, Jie Huang, Zhili Ding, Qiang Jiang, Guangnan Yang, Zhaokun Lu, Jingbo Ma, Yan Zhang, Yu Ding   +8 more
openalex   +1 more source

Nrf2-Keap1 Pathway and NLRP3 Inflammasome in Parkinson's Disease: Mechanistic Crosstalk and Therapeutic Implications. [PDF]

Mol Neurobiol
Jain R, Vora L, Nathiya D, Khatri DK.
europepmc   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

ML345 is a potent and selective NLRP3 inflammasome inhibitor with anti-inflammatory activity. [PDF]

Mol Biomed
Lin H, Liang X, Hao W, Lu X, Li B, Wang X.   +5 more
europepmc   +1 more source

Bridging Psychological Stress and Skin Cellular Aging: Flavonoids as a Dual‐Action Therapeutic Strategy

Phytotherapy Research, EarlyView.
ABSTRACT Psychological stress (or simply “stress”) is a major contributor to chronic disease worldwide, affecting 35% of the global population, including younger generations. Furthermore, it plays a significant role in human premature aging; hence, its detrimental effects on people's health compel us to comprehend and control the ways in which ...
Marco Duarte, Sílvia Santos Pedrosa, P. Raaj Khusial, Ana Raquel Madureira   +3 more
wiley   +1 more source

Diverse functions of NLRP3 inflammasome in PANoptosis and diseases. [PDF]

Cell Death Discov
Jiang Y, Qiang Z, Liu Y, Zhu L, Xiao L, Du Z, Cai R, Qiang S.   +7 more
europepmc   +1 more source

Long‐term remission in gout: Challenges and future opportunities

Rheumatology &Autoimmunity, EarlyView.
Prolonged hyperuricemia is a major risk factor for gout, which is now regarded as a curable disease. Awareness of the various factors that can trigger gout flares is essential for their prevention. An important determinant of treatment decisions and long‐term follow‐up is the quality of the clinician–patient relationship. The “treat‐to‐target” approach
Patapong Towiwat, Zhanguo Li
wiley   +1 more source

Cigarette smoking induces NLRP3 inflammasome activation in patients with atrial fibrillation. [PDF]

Am J Physiol Heart Circ Physiol
Sarode G, Diloretto DA, Roslan FF, Pandita P, Overton J, Srivatsa U, Catrip JM, Liem DA, Bang H, Cadeiras M, Chiamvimonvat N, Sirish P.   +11 more
europepmc   +1 more source

Activation of Nlrp3 Inflammasomes Enhances Macrophage Lipid-Deposition and Migration: Implication of a Novel Role of Inflammasome in Atherogenesis

, 2014
Xiang Li, Yang Zhang, Min Xia, Erich Gulbins, Krishna M. Boini, Pin‐Lan Li   +5 more
openalex   +2 more sources