Results 91 to 100 of about 157,319 (379)

A synthetic cell-penetrating peptide derived from nuclear localization signal of EPS8 exerts anticancer activity against acute myeloid leukemia

open access: yesJournal of Experimental & Clinical Cancer Research, 2018
Background Oncogenic roles of epidermal growth factor receptor pathway substrate no.8 (EPS8) have been widely reported in various tumors, making targeting of EPS8 an appealing prospect.
Yiran Chen   +6 more
doaj   +1 more source

Interplay between kinase domain autophosphorylation and F-actin binding domain in regulating imatinib sensitivity and nuclear import of BCR-ABL. [PDF]

open access: yesPLoS ONE, 2011
The constitutively activated BCR-ABL tyrosine kinase of chronic myeloid leukemia (CML) is localized exclusively to the cytoplasm despite the three nuclear localization signals (NLS) in the ABL portion of this fusion protein.
Martin Preyer   +2 more
doaj   +1 more source

Nonlocal nonlinear Schrödinger equation and its discrete version: soliton solutions and gauge equivalence [PDF]

open access: yes, 2015
In this paper, we try to understand the geometry for a nonlocal nonlinear Schr\"{o}dinger equation (nonlocal NLS) and its discrete version introduced by Ablowitz and Musslimani. We show that, under the gauge transformations, the nonlocal focusing NLS and the nonlocal defocusing NLS are, respectively, gauge equivalent to a Heisenberg-like equation and a
arxiv   +1 more source

KAM for Beating Solutions of the Quintic NLS [PDF]

open access: yes, 2016
We consider the nonlinear Schrödinger equation of degree five on the circle $${\mathbb{T}= \mathbb{R} / 2\pi}$$T=R/2π. We prove the existence of quasi-periodic solutions with four frequencies which bifurcate from “resonant” solutions [studied in Grébert ...
E. Haus, M. Procesi
semanticscholar   +1 more source

Single Pair of Weyl Points Evolve From Spin Group‐Protected Nodal Line in Half‐Metallic Ferromagnet V3S4

open access: yesAdvanced Functional Materials, EarlyView.
A spin group (SG)‐based mechanism is proposed to realize a single pair of Weyl points. PT‐symmetric nodal lines (NLs) persist under T‐breaking, protected by the combination of SG and P symmetry. When considering spin‐orbit coupling, the SG‐protected NL will split into Weyl points, which will also induce anomalous transport phenomena arising from ...
Shifeng Qian   +6 more
wiley   +1 more source

7 Tesla magnetic resonance imaging to detect cortical pathology in multiple sclerosis. [PDF]

open access: yesPLoS ONE, 2014
Neocortical lesions (NLs) are an important pathological component of multiple sclerosis (MS), but their visualization by magnetic resonance imaging (MRI) remains challenging.We aimed at assessing the sensitivity of multi echo gradient echo (ME-GRE) T2 ...
Bing Yao   +7 more
doaj   +1 more source

Nuclear Exportin 1 (XPO1) Binds to the Nuclear Localization/Export Signal of the Turnip Mosaic Virus NIb to Promote Viral Infection

open access: yesFrontiers in Microbiology, 2022
The nuclear localization signal (NLS) and nuclear export signal (NES) are key signatures of proteins for controlling nuclear import and export. The NIb protein of turnip mosaic virus (TuMV) is an RNA-dependent RNA polymerase (RdRP) that is absolutely ...
Mingzhen Zhang   +11 more
doaj   +1 more source

Predicting rogue waves in random oceanic sea states [PDF]

open access: yes, 2004
Using the inverse spectral theory of the nonlinear Schrodinger (NLS) equation we correlate the development of rogue waves in oceanic sea states characterized by the JONSWAP spectrum with the proximity to homoclinic solutions of the NLS equation.
Islas, Alvaro, Schober, Constance
core   +4 more sources

Three-dimensional context rather than NLS amino acid sequence determines importin α subtype specificity for RCC1

open access: yesNature Communications, 2017
Active nuclear import of Ran exchange factor RCC1 is mediated by importin α3. This pathway is essential to generate a gradient of RanGTP on chromatin that directs nucleocytoplasmic transport, mitotic spindle assembly and nuclear envelope formation.
R. Sankhala   +5 more
semanticscholar   +1 more source

On the continuous resonant equation for NLS II: Statistical study [PDF]

open access: yes, 2015
We consider the continuous resonant (CR) system of the 2D cubic nonlinear Schrodinger (NLS) equation. This system arises in numerous instances as an effective equation for the long-time dynamics of NLS in confined regimes (e.g.
P. Germain, Z. Hani, Laurent Thomann
semanticscholar   +1 more source

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